A5090644104- Dental Implant Techniques and Outcomes
- Dental Radiography and Imaging
- Periodontal Regeneration and Treatments
- Dental materials and restorations
- Bone Tissue Engineering Materials
- Orthodontics and Dentofacial Orthopedics
- RNA modifications and cancer
- Cancer-related gene regulation
- Dental Health and Care Utilization
- Dental Research and COVID-19
- Genomics and Chromatin Dynamics
- Dental Anxiety and Anesthesia Techniques
- Cleft Lip and Palate Research
- Epigenetics and DNA Methylation
- Cancer-related molecular mechanisms research
- dental development and anomalies
- Genomic variations and chromosomal abnormalities
- Electrospun Nanofibers in Biomedical Applications
- Shoulder Injury and Treatment
- Surgical Sutures and Adhesives
- TGF-β signaling in diseases
- Anatomy and Medical Technology
- MicroRNA in disease regulation
- Cancer Genomics and Diagnostics
- Protease and Inhibitor Mechanisms
Chulalongkorn University
2016-2025
National Medical Research Center of Dentistry and Maxillofacial Surgery
2015
Tokyo Medical and Dental University
2000-2011
Bangkok Hospital
2006
Abstract Aim This randomized controlled clinical trial (RCT) aimed to compare the accuracy of implant positions between static computer‐assisted surgery (CAIS) and freehand in a single edentulous space. Materials methods Sites with spaces neighbouring natural teeth were into CAIS or groups. In both groups, digital planning was performed using data from cone beam computed tomography (CBCT) surface scans. group, surgical guide produced used for fully guided surgery, while implants placed...
Abstract Objectives The aim of this RCT was to compare the accuracy implant placement between static and dynamic computer‐assisted surgery (CAIS) systems in single tooth space. Materials methods A total 60 patients need a were randomly assigned two CAIS groups (Static n = 30, Dynamic 30) implants placed by one surgeon. Preoperative CBCT transferred planning software plan optimal position. Implants using either stereolithographic guide template CAIS) or navigation system (Dynamic CAIS)....
Abstract Human gingival fibroblasts (HGFs), a predominant cell type in tooth-supporting structure, are presently recognized for their active role the innate immune response. They produce variety of inflammatory cytokines response to microbial components such as LPS from key periodontal pathogen, Porphyromonas gingivalis. In this study, we demonstrated that HGFs expressed mRNA TLRs 1, 2, 3, 4, 5, 6, and 9, but not 7, 8, 10. Stimulation with highly purified TLR2 ligand (P. gingivalis LPS),...
Abstract Background Computer‐assisted implant surgery (CAIS) can facilitate accuracy of single placement, but little is known with regards to parallelism between multiple implants. Purpose To compare the position and two implants, using static dynamic CAIS systems. Materials methods Thirty patients received implants (60 implants) randomly allocated different Optimal absolute was planned based on preoperative cone beam CT (CBCT). Patients a surgical guide (static CAIS, n = 30) or real‐time...
Abstract Objective To compare implant accuracy of combined static and dynamic (SD) computer‐assisted surgery (CAIS) with (S), (D) CAIS, freehand (FH) for single placement. Materials Methods One hundred twenty patients were randomized into four groups. Implants placed using both stereolithographic surgical guide navigation in the SD group, S D conventional FH group. Analysis deviation between planned final position, as well K means analysis was conducted at platform, apex, angle (primary...
Phosphatidylinositol 3‐kinases (PI3K) are a group of heterodimeric lipid kinases that regulate many cellular processes. Gene amplification and somatic mutations mainly within the helical (exon 9) kinase 20) domains PIK3CA , which encode 110‐kDa catalytic subunit PI3K mapped to 3q26, have been reported in various human cancers. Herein, 14 oral squamous cell carcinoma (OSCC) lines 108 primary OSCC tumors were investigated for activating at exons 9 20 as well amplifications . missense...
Abstract Objectives To assess navigation accuracy for complete‐arch implant placement with immediate loading of digitally prefabricated provisional. Materials and Methods Consecutive edentulous terminal dentition patients requiring at least one FDP were treated between December 2020 January 2022. Accuracy was evaluated by superimposing pre‐operative post‐operative cone beam computed tomography (CBCT), recording linear (mm) angular (degrees) deviations. T‐tests performed to investigate the...
Array‐based comparative genomic hybridization (array‐CGH) has good potential for the high‐throughput identification of genetic aberrations in cell genomes. In course a program to screen panel 21 oral squamous‐cell carcinoma (OSCC) lines genome‐wide copy‐number by array‐CGH using our in‐house bacterial artificial chromosome arrays, we identified frequent homozygous deletion at 4q35 loci with approximately 1 Mb extent. Among seven genes located within this region, expression melatonin receptor...
The incidence and mortality statistics for oral squamous cell carcinoma (OSCC) were 10th 12th, respectively, in human cancers diagnosed worldwide 2008. In this study, to identify novel tumor-suppressive microRNAs (TS-miRNAs) their direct targets OSCC, we performed methylation-based screening 43 miRNAs encoded by 46 miRNA genes located within 500bp downstream of 40 CpG islands genome-wide gene expression profiling combination with a prediction database analysis, 18 lines, resulting the...
Abstract Background Different designs of surgical drilling systems have been developed for the purpose static Computer‐Assisted Implant Surgery (sCAIS), but there is at present little understanding how design principles affect accuracy implant placement. Purpose The aim this in vitro study was to compare placement among five sCAIS a controlled experimental setting. Materials and Methods Twenty‐five 3D printed models with two edentulous bilateral premolar spaces were allocated different...
Chitosan/dicarboxylic acid (CS/DA) scaffold has been developed as a bone tissue engineering material. This study evaluated CS/DA with and without seeded primary human periodontal ligament cells (hPDLCs) in its capacity to regenerate calvarial defects of mice. The osteogenic differentiation hPDLCs was analyzed by nodule formation gene expression. In vivo regeneration mice defects. Eighteen were divided into 3 groups: one group empty defects, scaffold, hPDLCs. After 6 12 weeks, new assessed...