A5081682818- Esophageal and GI Pathology
- Gastric Cancer Management and Outcomes
- Esophageal Cancer Research and Treatment
- Pregnancy and preeclampsia studies
- Metastasis and carcinoma case studies
- Gestational Diabetes Research and Management
- Gastrointestinal Tumor Research and Treatment
- Lung Cancer Diagnosis and Treatment
- Pancreatic and Hepatic Oncology Research
- Birth, Development, and Health
- Colorectal Cancer Screening and Detection
- Lung Cancer Treatments and Mutations
- Hormonal Regulation and Hypertension
- Cerebral Palsy and Movement Disorders
- Lung Cancer Research Studies
- Minimally Invasive Surgical Techniques
- Gallbladder and Bile Duct Disorders
- Colorectal Cancer Surgical Treatments
- Fungal Biology and Applications
- Adrenal and Paraganglionic Tumors
- Cancer Cells and Metastasis
- Pancreatitis Pathology and Treatment
- Reproductive System and Pregnancy
- Clinical Nutrition and Gastroenterology
- Prenatal Substance Exposure Effects
Fujian Medical University
2013-2025
Fudan University Shanghai Cancer Center
2024-2025
Yunnan University of Traditional Chinese Medicine
2024
Fujian Provincial Cancer Hospital
2008-2024
University of Science and Technology of China
2018-2024
Anhui Provincial Hospital
2018-2022
Heilongjiang Bayi Agricultural University
2022
Ministry of Agriculture and Rural Affairs
2022
Anhui Medical University
2018
Fuzhou General Hospital of Nanjing Military Command
2016
Abstract Coronavirus disease 2019 (COVID-19) is regarded as an endothelial (endothelialitis) with its patho-mechanism being incompletely understood. Emerging evidence has demonstrated that dysfunction precipitates COVID-19 and accompanying multi-organ injuries. Thus, pharmacotherapies targeting have potential to ameliorate cardiovascular complications. The objective of the present study evaluate whether kruppel-like factor 2 (KLF2), a master regulator vascular homeostasis, represents...
A 68-year-old man presented to our hospital with progressive dysphagia and retrosternal discomfort for 1 month. Endoscopy pathological biopsy confirmed invasive squamous cell carcinoma of the distal esophagus ([Fig. 1] a) poorly differentiated adenocarcinoma at junction gastric antrum body b). Following preoperative preparation, patient underwent subtotal esophagectomy, gastrectomy, anterograde ileo-colon interposition esophageal replacement via route.
The stilbenoids, arachidin-1 (Ara-1), arachidin-3, isopentadienylresveratrol, and resveratrol, have been isolated from germinating peanut kernels characterized as antioxidant anti-inflammatory agents. Resveratrol possesses anticancer activity, studies indicated that it induces programmed cell death (PCD) in human leukemia HL-60 cells. In this study, the activity of these stilbenoids was determined Ara-1 had highest efficacy inducing PCD cells, with an approximately 4-fold lower EC50 than...
Diadenosine tetraphosphate (AP4A), an endogenous diadenosine polyphosphate, reduces ischemic injury in the heart. In this study, we report potent and protective effects of AP4A rodent models stroke Parkinson's disease. AP4A, given intracerebroventricularly before middle cerebral artery (MCA) ligation, reduced infarction size enhanced locomotor activity adult rats. The intravenous administration also induced protection when early after MCA ligation. suppressed terminal deoxynucleotidyl...
Pregnancy-induced hypertension (PIH) causes significant maternal and fetal morbidity mortality. A decreased number of regulatory T (Treg) cells is associated with the pathogenesis PIH. The programmed cell death-1 (PD-1)/PD-ligand 1 (PD-L1) pathway critical to normal pregnancy (NP) by promoting Treg development. However, relationship between PD-1/PD-L1 differentiation in PIH has not been fully elucidated. In this study, venous blood was obtained from 20 NP 58 patients. Peripheral mononuclear...
Saline-alkali (SA) stress induces excessive reactive oxygen species (ROS) accumulation in plant cells, resulting oxidative damages of membranes, lipids, proteins, and nucleic acids. Melatonin has antioxidant protection effects living organisms thus received a lot attention. This study aimed to investigate the effect regulating mechanism melatonin treatment on soybean tolerance SA stress. In this study, cultivars Heihe 49 (HH49, SA-tolerant) Henong 95 (HN95, SA-sensitive) were pot-cultured...
OBJECTIVE-SUMO4 mRNA was recently found to be mainly expressed in the kidney, and methionine-to-valine substitution at codon 55 (M55V) variant of SUMO4 may induce higher nuclear factor-kappaB (NF-kappaB) activity. Because NF-kappaB is known mediate development diabetic nephropathy, we examined association between M55V severity nephropathy. RESEARCH DESIGN AND METHODS-We recruited a total 430 patients with type 2 diabetes. The (rs237025, 163A-->G) polymorphism genotyped by real-time PCR,...
The objective of this study was to investigate the effects c-Jun N-terminal kinase (JNK) signaling pathway on rats' acute pancreatitis-associated lung injury (APALI).Seventy-two Sprague-Dawley rats were randomly divided into 3 groups, namely, sham operation (SO) group, severe pancreatitis (SAP) and SP600125 group. SAP model established by injection 5% sodium taurocholate pancreatic duct. samples taken at 3, 6, 12, 24 hours. Serum amylase, pathologic lesions pancreas tissues, wet-to-dry...
Background/Aim: The purpose of this study was to evaluate the clinical significance visualized area percentage assessment cleansing score (AAC) and computed (CAC) these two small bowel cleanliness scores systems for capsule endoscopy (CE). Materials Methods: reliability consistency AAC CAC were evaluated by comparing examiners (one expert, one without any training in CE). Reliability determined using intraclass correlation coefficient (ICC) kappa statistic. Results: inter-observer agreement...
Klinefelter's syndrome is rarely associated with hypocalcemia, especially pseudohypoparathyroidism (PHP) type Ib. We describe a case of seizure, PHP Ib and multiple endocrine dysfunctions. A 19-year-old Taiwanese male was admitted due to seizures loss consciousness. He had been diagnosed seizure disorder hypocalcemia 3 months previously. Physical examination revealed eunuchoidism but no osteodystrophy, while laboratory data severe hyperphosphatemia, elevated parathyroid hormone. Chromosomal...
A rare type of aldosteronism, known as unilateral adrenal hyperplasia (UAH), is difficult to diagnose, not only because it fails conform the typical common subtypes, but also imaging results are unreliable. We report 2 Taiwanese patients with UAH. Case 1 was a 44-year-old man episodes hypokalemic paralysis. Hypertension and suppressed plasma renin activity (PRA) elevated aldosterone concentration (PAC) were observed. Abdominal computed tomography (CT) magnetic resonance (MRI) showed right...
Cerebral palsy (CP) is a refractory pediatric disease with high prevalence, disability rate, and difficult treatment. A variety of treatments are currently used for CP. The treatment involves drug non-drug therapy. Traditional Chinese medicine external therapy very distinctive method in As one the therapies traditional medicine, massage treating cerebral has good efficacy, small side effects, strong operability. part TCM therapy, selective spinal manipulation can effectively promote growth...
Background: Understanding the difference in etiology and pregnancy outcome of gestational diabetes (GDM) subtypes is crucial for prenatal care GDM prevention strategies. We aimed to explore insulin physiology distinct by fasting hyperglycemia or post-load hyperglycemia.Methods: conducted a prospective cohort pregnant women (n=2667) between October 1, 2021 January 2024. Women were categorized into normoglycemia (NGT, n=936), isolated impaired glucose (gestational-IFG, n=378), tolerance...
Objective This paper summarizes the research progress into stimulation methods used in rehabilitation equipment for pediatric cerebral palsy (CP) past 20 years from 2003 to 2023. We also provide ideas innovative and development of artificial intelligence-based equipment. Methods Through a certain search strategy, Keywords are searched China National Knowledge Network Database (CNKI), Wanfang knowledge service platform, Chongqing VIP information service, PubMed, Web Science, Cochrane,...