A5101649979- Neuroendocrine regulation and behavior
- Neurotransmitter Receptor Influence on Behavior
- Receptor Mechanisms and Signaling
- Stress Responses and Cortisol
- Hypothalamic control of reproductive hormones
- Neuropeptides and Animal Physiology
- Gut microbiota and health
- Autism Spectrum Disorder Research
- Protein Structure and Dynamics
- Regulation of Appetite and Obesity
- Lipid Membrane Structure and Behavior
- Memory and Neural Mechanisms
- Neuroscience and Neuropharmacology Research
- Infant Health and Development
- Diet and metabolism studies
- Biochemical Analysis and Sensing Techniques
- Olfactory and Sensory Function Studies
- Sleep and Wakefulness Research
- Neural dynamics and brain function
- Crystallography and molecular interactions
- Neurology and Historical Studies
- Parkinson's Disease Mechanisms and Treatments
- Sphingolipid Metabolism and Signaling
- Polymer Science and Applications
- Peroxisome Proliferator-Activated Receptors
University of Pecs
2015-2025
Czech Academy of Sciences, Institute of Physiology
2024-2025
Eötvös Loránd University
2021
American Chemical Society
1996
American Society of Mechanical Engineers
1996
American Society For Testing and Materials
1996
Istituto di Chimica Biomolecolare
1966-1981
University of Bologna
1975
Abstract The prevalence of autism spectrum disorder (ASD) has rapidly increased in the past decades, and several studies report about escalating use antibiotics consequent disruption gastrointestinal microbiome leading to development neurobehavioral symptoms resembling those ASD. primary purpose this study was investigate whether depletion via treatment could induce ASD-like behavioral adulthood. To reliably evaluate that, validated valproic acid (VPA) ASD animal model introduced. At last,...
Abstract Background The tachykinin substance P (SP) facilitates learning and memory processes after its central administration. Activation of different receptive sites, neurokinin-1 receptors (NK1Rs), as well NK2Rs NK3Rs was shown to influence memory. basal ganglia have been confirmed play an important role in the control spatial mechanisms, part ganglia, globus pallidus (GP) may also be involved this regulation. SP-immunoreactive fibers terminals, NK1Rs NK3Rs, were present GP. Methods study...
Accurate and reliable measurement of the electrical impedance spectrum is an essential requirement in order to draw relevant conclusions many fields a variety applications; particular, for biological processes. Even state-of-the-art methods developed this purpose, accuracy efficacy measurements are reduced systems, due regular occurrence parameters causing errors such as residual impedance, parasitic capacitance, generator anomalies, so on. Recent observations have reported necessity...
Crystals of the complex CaBr2.10H20.2(CHz)6H4are triclinic, space group P i, with a= 9"89_+ 0.02, b=9.75+0.02,c=9.58+0.02,~=94°29'_+ 12', /~= 100°39'+ y= 119°20'_+ Z= 1.The crystal structure has been determined by heavy-atom method and then refined three-dimensional Fourier synthesis several cycles differential synthesis.The is characterized layers parallel to (001), in which each hexamethylentetramine molecule links three different Ca(H20) 2+ octahedra Ca(H20)~ + octahedron six...
Neuropeptide oxytocin (OT) is involved in the regulation of social and non-social behaviour. The central nucleus amygdala (CeA), part limbic system, plays an important role learning, memory, anxiety reinforcing mechanisms. CeA has been shown to be rich OT receptors rodents. Our previous findings indicated that rat a dose dependent rewarding anxiolytic effect. aim our present study was examine possible interaction D2 dopamine (DA) receptor antagonist Sulpiride on reinforcement place...
Autism spectrum disorder (ASD) is a lifelong neurodevelopmental affecting about 1.5% of children, and its prevalence increasing. Anxiety one the most common comorbid signs ASD. Despite increasing prevalence, pathophysiology ASD still poorly understood, proper treatment has not been defined yet. In order to develop new therapeutic approaches, valproate- (VPA) induced rodent model autism can be an appropriate tool. Oxytocin (OT), as prosocial hormone, may ameliorate some symptoms
The goal of the present study is to investigate role intraamygdaloid oxytocin in learning-related mechanisms. Oxytocin a neuropeptide which involved social bonding, trust, emotional responses and various behaviors. By conducting passive avoidance Morris water maze tests on male Wistar rats, memory performance learning was investigated. doses 10 ng 100 were injected into central nucleus amygdala. Our results showed that significantly reduced time required locate platform during test while...
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTStructure of the Complex CaBr2·10H2O·2(CH2)6N4P. De Santis, A. L. Kovacs, M. Liquori, and MazzarellaCite this: J. Am. Chem. Soc. 1965, 87, 21, 4965–4966Publication Date (Print):November 1, 1965Publication History Published online1 May 2002Published inissue 1 November 1965https://pubs.acs.org/doi/10.1021/ja00949a058https://doi.org/10.1021/ja00949a058research-articleACS PublicationsRequest reuse permissionsArticle Views34Altmetric-Citations9LEARN...
Stress disorders impair sleep and quality of life; however, their pathomechanisms are unknown. Prolactin-releasing peptide (PrRP) is a stress mediator; we therefore hypothesized that PrRP may be involved in the development disorders. produced by medullary A1/A2 noradrenaline (NA) cells, which transmit signals to forebrain centers, non-NA cells hypothalamic dorsomedial nucleus. We found male rats both PrRP-NA innervate melanin-concentrating hormone (MCH) producing neurons dorsolateral...
Background: autism spectrum disorder (ASD) is a neurodevelopmental affecting around 1 out of 68 children and its incidence shows an increasing tendency. There currently no effective treatment for ASD. In research, the valproate (VPA)-induced rodent model widely accepted. Our previous results showed that intraamygdaloid oxytocin (OT) has anxiolytic effects on rats showing autistic signs under VPA-induced model. Methods: were stereotaxically implanted with guide cannulae bilaterally received...