Jiming Chen

ORCID: 0000-0002-0238-9158
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About
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Research Areas
  • Uterine Myomas and Treatments
  • Endometriosis Research and Treatment
  • Endometrial and Cervical Cancer Treatments
  • Minimally Invasive Surgical Techniques
  • Gynecological conditions and treatments
  • MicroRNA in disease regulation
  • Pelvic floor disorders treatments
  • Menopause: Health Impacts and Treatments
  • Ovarian cancer diagnosis and treatment
  • Estrogen and related hormone effects
  • Circular RNAs in diseases
  • Cardiovascular Function and Risk Factors
  • Ubiquitin and proteasome pathways
  • Cancer-related molecular mechanisms research
  • Prenatal Screening and Diagnostics
  • Intestinal and Peritoneal Adhesions
  • Medical Research and Treatments
  • Anorectal Disease Treatments and Outcomes
  • Cardiovascular Disease and Adiposity
  • Phytoestrogen effects and research
  • Medical Education and Admissions
  • Dementia and Cognitive Impairment Research
  • Lipid metabolism and disorders
  • Cancer Cells and Metastasis
  • Blood Pressure and Hypertension Studies

Huzhou Central Hospital
2024

Changzhou No.2 People's Hospital
2017-2024

Nanjing Medical University
2017-2024

Zhejiang University
2024

The First Affiliated Hospital, Sun Yat-sen University
2022

Sun Yat-sen University
2022

First Affiliated Hospital of Fujian Medical University
2012

Fujian Medical University
2012

Guangdong Medical College
2006

New York State Psychiatric Institute
1994

Endometrial carcinoma (EC) is the most common and lethal malignancy worldwide. Syncytin-1 expressed in multiple types of cancer. However, expression pattern potential mechanism syncytin-1 its clinical significance EC remain unclear.We analyzed 130 primary specimens from Binzhou Medical University to investigate role by using different advanced pathological stages tissues. Kaplan-Meier analysis was used measure overall survival patients. Western blot assays HECCL-1 RL-95-2 cells. Cell...

10.2147/ott.s191041 article EN OncoTargets and Therapy 2018-12-01

With the development and progress of society, people's average life expectancy has increased, relevant literature reports that number postmenopausal women in China continues to increase. lifespans extended, transition period post-menopause have become longest essential every woman's life. The quality troubled by perimenopausal syndrome been significantly reduced, which also places a burden on families society. It is well known hormone replacement therapy plays vital role improving women's...

10.1515/biol-2022-0754 article EN cc-by-nc-nd Open Life Sciences 2023-01-01

Background Endometriosis (EMS) is an estrogen-dependent disease, which easily recurs after operation. Gonadotropin-releasing hormone agonist (GnRH-a), estrogen-inhibiting drug, can effectively inhibit the secretion of gonadotropin by pituitary gland, so as to significantly decrease ovarian level and facilitate atrophy ectopic endometrium, playing a positive role in preventing postoperative recurrence. The application GnRH-a lead secondary low estrogen symptoms, namely perimenopausal main...

10.3389/fendo.2021.683552 article EN cc-by Frontiers in Endocrinology 2021-12-24

Abstract Mesonephric-like adenocarcinoma is a new class of rare subtypes the female reproductive system. Its clinical symptoms are similar to other types ovarian tumors. The diagnosis based on pathological and immunohistochemical methods. main treatment option surgery combined with chemotherapy. Few cases have been reported at home abroad. We case 45-year-old woman cystic solid mass in left adnexa. postoperative was mesonephric-like ovary mature teratoma (partial infiltration small...

10.1186/s13048-024-01383-7 article EN cc-by Journal of Ovarian Research 2024-03-05

Background: Cervical cancer (CC) is a common gynecological malignancy with high risk of recurrence and death. Circular RNAs play crucial role in the occurrence development tumors. This study aimed to investigate function mechanism circ_0000745 CC. Materials Methods: The levels circ_0000745, miR-409-3p, activating transcription factor 1 (ATF1) were determined by quantitative real-time polymerase chain reaction or Western blot assay. Cell proliferation was assessed colony formation migration...

10.1089/cbr.2019.3392 article EN Cancer Biotherapy and Radiopharmaceuticals 2020-07-09

Background Endometriosis (EMS) is a relapsing and estrogen-dependent disease. For endometriosis such as deep ovarian endometrioid cysts, surgery the most effective treatment. Long-term follow-up showed that recurrence rate of after surgical treatment was high, so postoperative drugs were needed to reduce recurrence, Gonadotropin-releasing hormone agonists (GnRH-a) commonly used drug for management.GnRH-a may post-treatment relapses by lowering levels in body. However, use GnRH-a can give...

10.3389/fendo.2022.854345 article EN cc-by Frontiers in Endocrinology 2022-06-09

<b><i>Introduction:</i></b> The aim of this study was to investigate the expression and predictive value NOD-like receptor thermal protein domain-related 3 (NLRP3) in patients with non-valvular atrial fibrillation (NVAF) heart failure preserved ejection fraction (HFpEF). <b><i>Methods:</i></b> This a retrospective analysis 121 diagnosed NVAF. According occurrence HFpEF, 81 were assigned NVAF group 40 NVAF/HFpEF group. levels NLRP3, B...

10.1159/000540204 article EN Cardiology 2024-07-17

Abstract Transumbilical single-port laparoscopy is widely used in gynecological surgery. However, it rarely the treatment of deep infiltrating endometriosis due to its own shortcomings and complex condition endometriosis. The study aims introduce a transumbilical laparoscopic surgery based on retroperitoneal pelvic spaces anatomy, which can complete operation more easily. A retrospective analysis 63 patients with treated by using this method was conducted. duration 120.00 (85.00 ± 170.00)...

10.1038/s41598-023-38034-8 article EN cc-by Scientific Reports 2023-07-04

Abstract The Medication Management (MM) Test is a new technique for measuring high‐level adaptive functioning in early dementia. Scoring based on direct observation of the subject's performance structured task, simulating calculations and manipulations involved self‐administration medications. equipment lightweight, small portable. Procedures are brief readily administered with little training. It congruent general health inquiry not threatening to self‐image. sensitivies specificities...

10.1002/gps.930091104 article EN International Journal of Geriatric Psychiatry 1994-11-01

Cervical cancer is a common gynecological malignancy. In addition to the open radical hysterectomy (ORH) and laparoscopic (LRH), nerve-sparing (LNSRH) could be another treatment option since it preserve urinary, colorectal, sexual functions. However, LNSRH might result in early metastasis recurrence due inadequate tumor resection. Additionally, whether should considered based on perineural invasion (PNI) status remains controversial. To assess different types of outcome cervical with PIN.A...

10.3389/fonc.2022.889862 article EN cc-by Frontiers in Oncology 2022-04-29

The specific objective of this investigation is to explore the impact miR-198 on proliferation, migration as well invasion ovarian cancer (OC) cells.OC tissue and adjacent normal samples from OC patients were collected, human epithelial cell IOSE80 lines SKOV3, Caov3, A2780 OVCAR3 selected in study for investigation. MiR-198 expression level was assessed using RT-qPCR. MTT, colony formation assay, Transwell wound healing flow cytometry adopted analyze role OVCAR invasion, migration,...

10.18388/abp.2020_5546 article EN cc-by Acta Biochimica Polonica 2021-06-28

This study was aimed to investigate the attitudes and knowledge of medical personnel on hormone replacement therapy (HRT) in treating perimenopausal syndrome. A total 2580 self-administered questionnaire forms were sent care professionals responses collected anonymous. The included information levels awareness, benefits, potential risks HRT. 2158 filled used for statistical analysis; 61.4% gynecologists believed that it necessary conduct HRT suitable patients, 89.1% would like recommend...

10.1080/09513590.2017.1405929 article EN Gynecological Endocrinology 2017-11-22

The aim was to investigate the outcome of vaginal delivery full-term pregnancies in patients after transvaginal-natural orifice transluminal endoscopic surgery (vNOTES) treatment for gynecological disorders.A case series report.A medical university hospital.12 cases successful surgery.Long-term follow-up with fertility needs surgery.From 2018 2021, 163 diseases were treated by vNOTES. One hundred forty-seven followed up, a rate 90.1%. average time 28 (15-47) months, including 66...

10.3389/fsurg.2022.888281 article EN cc-by Frontiers in Surgery 2022-04-28

To study the efficacy and safety of transvaginal natural orifice transluminal endoscopic Sacrospinous Ligament Fixation in treatment moderate severe pelvic organ prolapse. Patients were selected into this on a voluntary basis to evaluate short-term surgery by comparing OP-Q scores before operation, three months after six operation. Evaluate clinical retrospective analysis data 18 patients with POP-Q grade III-IV prolapse treated Department Gynecology Nanjing Medical University Affiliated...

10.3389/fsurg.2022.931691 article EN cc-by Frontiers in Surgery 2022-07-29

As a rare obstetric disease, fetomaternal hemorrhage (FMH) often causes severe fetal anemia, edema and even death, easily to be confused with neonatal asphyxia. Currently, there are several ways detect or predict FMH, however, most of them flawed time-consuming, as well unsuitable for rapid diagnosis timely intervention FMH. To explore the values umbilical artery blood gas analysis in providing basis guidance newborn rescue. Five cases neonates FMH from First Affiliated Hospital Army...

10.1097/md.0000000000038249 article EN cc-by-nc Medicine 2024-05-31

<title>Abstract</title> <bold>Background: </bold>Single-port laparoscopic surgery offers unique minimally invasive and cosmetic results facilitates the patient's postoperative recovery.In transumbilical single-port myomectomy, suturing of uterine wound is a critical intraoperative step.Due to difficulty operating with single hole, it takes longer suture wound, which somewhat increases potential risk limits development this procedure.This study describes technique "suture formula" compares...

10.21203/rs.3.rs-5345088/v1 preprint EN 2024-10-30

Metabolic syndrome is a pre-diabetes condition that associated with increased cardiovascular morbidity and mortality. We aimed to explore how exercise capacity, cardiac structure, function were affected in patients metabolic syndrome. Outpatients echocardiography stress test combined impedance cardiography (ETT + ICGG) results available from Nov 2018 Oct 2020 retrospectively enrolled. Echocardiographic, ETT ICG profiles, performance compared between the ones without. Sensitivity analyses...

10.3389/fcvm.2022.974802 article EN cc-by Frontiers in Cardiovascular Medicine 2022-08-11
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