Xianqi Huang
- Acute Lymphoblastic Leukemia research
- HER2/EGFR in Cancer Research
- Cell Adhesion Molecules Research
- Chronic Myeloid Leukemia Treatments
- Childhood Cancer Survivors' Quality of Life
- Cytokine Signaling Pathways and Interactions
Institute of Hematology & Blood Diseases Hospital
2022-2023
Chinese Academy of Medical Sciences & Peking Union Medical College
2022-2023
Aims: To analyze the methylation level in promoter region of SLC19A1 adult acute lymphoblastic leukemia (ALL) patients, and explore relationship between methotrexate (MTX) drug metabolism methylation. Methods: The levels 52 ALL patients who received high-dose MTX chemotherapy were retrospectively analyzed combination with clinical indicators plasma concentration. Results: Methylation 17 CpG units differently correlated parameters including gender, age, immunophenotype Philadelphia chromosome...