Karissa Weidman

ORCID: 0000-0003-0759-9346
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About
Contact & Profiles
Research Areas
  • COVID-19 Clinical Research Studies
  • Long-Term Effects of COVID-19
  • Intensive Care Unit Cognitive Disorders
  • COVID-19 and Mental Health
  • Immune responses and vaccinations
  • COVID-19 Impact on Reproduction
  • Enzyme Structure and Function
  • Lipid metabolism and disorders
  • SARS-CoV-2 and COVID-19 Research
  • Platelet Disorders and Treatments
  • Health disparities and outcomes
  • Family and Patient Care in Intensive Care Units
  • Respiratory Support and Mechanisms
  • Immune cells in cancer
  • Sulfur Compounds in Biology
  • Protein Hydrolysis and Bioactive Peptides

Stony Brook School
2024

Stony Brook University
2024

Weill Cornell Medicine
2021-2023

Cornell University
2021-2023

New York Hospital Queens
2021-2022

NewYork–Presbyterian Hospital
2021-2022

Presbyterian Hospital
2021-2022

Wake Forest University
2013

Rationale: The coronavirus disease (COVID-19) pandemic has led to a dramatic increase in the number of survivors critical illness. These are at increased risk for physical, psychological, and cognitive impairments known collectively as post-intensive care syndrome (PICS). Little is about prevalence PICS COVID-19 survivors. Objectives: To report impairment among intensive unit (ICU) receiving follow-up an ICU recovery clinic, assess associations between ICU-related factors, compare cohort who...

10.1513/annalsats.202104-520oc article EN cc-by-nc-nd Annals of the American Thoracic Society 2021-12-22

Abstract Severe coronavirus disease 2019 (COVID-19) is characterized by systemic inflammation and can result in protracted symptoms. Robust may trigger persistent changes hematopoietic cells innate immune memory through epigenetic mechanisms. We reveal that rare circulating stem progenitor (HSPC), enriched from human blood, match the diversity of HSPC bone marrow, enabling investigation hematopoiesis epigenomics. Following COVID-19, retain epigenomic alterations are conveyed,...

10.1101/2022.02.09.479588 preprint EN cc-by-nc-nd bioRxiv (Cold Spring Harbor Laboratory) 2022-02-10

BshB, a key enzyme in bacillithiol biosynthesis, hydrolyses the acetyl group from N-acetylglucosamine malate to generate glucosamine malate. In Bacillus anthracis, BA1557 has been identified as deacetylase (BshB); however, high content of (~70%) was still observed B. anthracis ∆BA1557 strain. Genomic analysis led proposal that another could exhibit cross-functionality biosynthesis. present study, BA1557, its paralogue BA3888 and orthologous cereus enzymes BC1534 BC3461 have characterized for...

10.1042/bj20130415 article EN Biochemical Journal 2013-06-12

ABSTRACT Vascular injury is a menacing element of acute respiratory distress syndrome (ARDS) pathogenesis. To better understand the role vascular in COVID-19 ARDS, we used lung autopsy immunohistochemistry and blood proteomics from subjects at distinct timepoints disease pathogenesis, including hospitalized cohort risk ARDS development (“ risk” , N=59), an intensive care unit with ( “ARDS ”, N=31), recovering recovery N=12). tissue revealed association between platelet-rich microthrombi....

10.1101/2021.05.20.21257542 preprint EN cc-by-nc-nd medRxiv (Cold Spring Harbor Laboratory) 2021-05-24
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