- Infant Development and Preterm Care
- Neonatal and fetal brain pathology
- Cerebral Palsy and Movement Disorders
- Neonatal Respiratory Health Research
- Family and Disability Support Research
- Healthcare Decision-Making and Restraints
- Pharmaceutical Practices and Patient Outcomes
- Respiratory Support and Mechanisms
- Language Development and Disorders
- Schizophrenia research and treatment
- Congenital Heart Disease Studies
Norfolk and Suffolk NHS Foundation Trust
2025
Lurie Children's Hospital
2019-2024
Northwestern Medicine
2024
Background: Early identification of cerebral palsy (CP) during infancy will provide opportunities for early therapies and treatments. The aim the present study was to a novel machine-learning model, Computer-based Infant Movement Assessment (CIMA) clinically feasible CP prediction based on infant video recordings. Methods: CIMA model designed assess proportion (%) risk-related movements using time–frequency decomposition movement trajectories infant’s body parts. developed tested recordings...
Early identification of cerebral palsy (CP) is important for early intervention, yet expert-based assessments do not permit widespread use, and conventional machine learning alternatives lack validity.
Rationale: Immature control of breathing is associated with apnea, periodic breathing, intermittent hypoxemia, and bradycardia in extremely preterm infants. However, it not clear if such events independently predict worse respiratory outcome. Objectives: To determine analysis cardiorespiratory monitoring data can unfavorable outcomes at 40 weeks postmenstrual age (PMA) other outcomes, as bronchopulmonary dysplasia 36 PMA. Methods: The Prematurity-related Ventilatory Control (Pre-Vent) study...
Background Psychotropic medicines are commonly prescribed as when required (PRN) prescriptions for inpatients anxiety, insomnia or part of a strategy to de-escalate situations that may lead violence and aggression. While these can provide benefit, safeguards need be in place ensure they regularly reviewed not overused. Aim methodology To (1) establish baseline practice around the clinical review psychotropic PRN (2) improve from end improvement programme. Centrally coordinated, locally...
Early prediction of cerebral palsy (CP) using the General Movement Assessment (GMA) during fidgety movements (FM) period has been recommended as standard care in high-risk infants. The aim this study was to determine accuracy GMA, alone or combination with neonatal imaging, predicting (CP).Infants increased risk perinatal brain injury were prospectively enrolled from 2009-2014 multi-center, observational study. FM classified by two certified GMA observers blinded clinical history. Abnormal...
Abstract Aim To describe the development of an observational measure spontaneous independent joint motion in infants with spastic cerebral palsy (CP), Baby Observational Selective Control AppRaisal (BabyOSCAR), and to test its convergent validity reliability. Method A retrospective sample 75 (45 CP 30 without CP) at 3 months age were scored BabyOSCAR compared diagnosis CP, limbs affected, Gross Motor Function Classification level 2 years or later for using t ‐tests, Kruskal–Wallis tests,...
Abstract Aim To assess the predictive capabilities of Baby Observational Selective Control AppRaisal (BabyOSCAR) tool, administered at 3 months corrected age, in determining spastic cerebral palsy (CP) outcome, functional abilities, and body topography 2 years age or later. Method Independent joint motions were measured 10 to 16 weeks from video recordings spontaneous movement using BabyOSCAR a sample 75 infants. All included infants had known 2‐year outcomes (45 with CP 30 without CP)...
The objective of this study was to investigate the influences on motor development in infants who are at low risk from Belgium, India, Norway, and United States using General Movement Assessment 10-16 weeks postterm age. This a cross-sectional prospectively enrolled full-term (n = 186). Certified observers rated fidgety movements, quality movement patterns, age-adequacy repertoire, postural character, overall Motor Optimality Score-Revised (MOS-R). Scores were evaluated for associations with...
Background/Objectives: Despite evidence of the effectiveness early intervention (EI) programs, eligible infants often experience delays in initiation services or fail to receive entirely. Disparities have been documented, including lower enrollment rates for with public insurance. The objective this pilot study was evaluate feasibility initiating home physical therapy (PT) promptly after neonatal cardiac intensive care unit (NICU/CICU) discharge insurance and assess motor outcomes children...