A5102728946- Pharmacological Effects and Toxicity Studies
- Pregnancy and Medication Impact
- Acute Ischemic Stroke Management
- Cerebrovascular and Carotid Artery Diseases
- Breastfeeding Practices and Influences
- Renal Transplantation Outcomes and Treatments
- Gastric Cancer Management and Outcomes
- Renal Diseases and Glomerulopathies
- Hemoglobinopathies and Related Disorders
- Prenatal Substance Exposure Effects
- Advanced Chemical Sensor Technologies
- Pregnancy and preeclampsia studies
- IgG4-Related and Inflammatory Diseases
- Dementia and Cognitive Impairment Research
- Chronic Kidney Disease and Diabetes
- Receptor Mechanisms and Signaling
- Esophageal Cancer Research and Treatment
- Medical Imaging and Analysis
- Complement system in diseases
- Epilepsy research and treatment
- Circadian rhythm and melatonin
- Folate and B Vitamins Research
- Aortic Thrombus and Embolism
- Spine and Intervertebral Disc Pathology
- Neuroendocrine Tumor Research Advances
Hokkaido University Hospital
2015-2024
Tokyo Women's Medical University Hospital
2021-2022
Hitachi (Japan)
2009-2022
Tokyo Women's Medical University
2018-2022
Kyoto Prefectural University of Medicine
2006-2021
National Cerebral and Cardiovascular Center
2020
Showa General Hospital
2018
Ebara (Japan)
2010
Hoshi University
2010
Mitsubishi Group (Japan)
2006
Objective: Benzodiazepines are common therapies for mental illness and insomnia, used during pregnancy lactation. Although benzodiazepines have been shown to be transferred into breast milk, the amount is small compatible with breastfeeding. However, information not available all drugs. Therefore, we aimed determine milk plasma (M/P) ratio relative infant dose (RID), which as indicators of drug transfer safety such drugs lactating women breastfeeding infants. Methods: The study comprised 11...
Notwithstanding the current guideline-based management, patients with stroke retain a substantial risk of further vascular events. We aimed to assess contribution atherogenic dyslipidemia (AD) this residual risk.This was prospective observational study, in which 792 (mean age, 70.1 years; male, 60.2%) acute ischemic (n=710) or transient attack (n=82) within 1 week onset were consecutively enrolled and followed for year. AD defined as having both elevated levels triglycerides ≥150 mg/dL low...
Most cells for regenerative medicine are currently cultured manually. In order to promote the widespread use of medicine, it will be necessary develop automated culture techniques so that can produced in greater quantities at lower cost and with more stable quality. field technology, cell sheet therapy is an effective tissue engineering technique whereby grafted by attaching them a target site. We have developed equipment this treatment. This features fully closed vessel circuit system...
Patients with vascular Ehlers-Danlos syndrome (EDS) occasionally suffer from arterial dissection. Eagle syndrome, which is caused by an elongated styloid process and also causes dissection, difficult to diagnose could sometimes be overlooked. Little known of the coexistence these two diseases, treatment strategy not established. Here, we present a case bilateral internal carotid artery (ICA) dissection due in patient EDS.A 30-year-old man was admitted our hospital because sudden onset mild...
Hypertriglyceridemia is perceived to promote atherosclerotic pathology, but its role in stroke has not been well defined. Our aim was assess the contribution of hypertriglyceridemia residual vascular risk patients with atherothrombotic stroke.The Tokyo Women's Medical University Stroke Registry an ongoing prospective, observational registry which 870 acute ischemic or TIA within 1 week onset were consecutively enrolled and followed up for year. defined as serum triglycerides levels ≥150...
Given the recent increase in prevalence of diabetes mellitus, it is not uncommon for kidney transplantation donors to have diabetes. We perform our hospital if diabetic are receiving oral hypoglycaemic agents, but insulin, and their haemoglobin A1C (HbA1C) below 6.5%. There few reports about histological changes nephropathy after grafts from with mellitus non-diabetic recipients. Therefore, we studied at protocol biopsies (1 hour, 1 month, year), evaluated whether they improved under...
Summary Identifying the depth of invasion (DOI) superficial esophageal squamous cell carcinoma (SESCC) is crucial to determine indication for endoscopic resection. This retrospective, single-center study aimed evaluate diagnostic efficacy magnifying blue laser imaging (M-BLI) compared with white-light (WLI) or narrow-band (M-NBI) identifying DOI SESCC. A total 160 consecutive patients SESCCs who underwent submucosal dissection were enrolled in this study. Still images lesion obtained using...
HSCT-associated thrombotic microangiopathy (TA-TMA) is a severe complication with poor prognosis. Recently, it has been reported that complement system dysregulation, such as CFH autoantibodies and deletions CFH-related genes 3 1, induced TA-TMA. In addition, C4d-positive renal arterioles are both good marker of activation useful diagnostic tool for Because dysregulation the associated TA-TMA, might be therapeutic target, eculizumab, terminal inhibitor. Herein, we describe an eight-yr-old...
This study aimed to identify the association between long term functional outcomes and acute ischemic stroke (AIS) in patients with heart failure (HF) Japan whether 1-year event risks can be related these patients.
Herein is described a unique renal cell tumor with previously unreported morphological and immunohistochemical features. The patient was 78‐year‐old Japanese man. A huge left found on ultrasound during evaluation of abdominal distention. macroscopically characterized by non‐infiltrative border, pale yellow to grayish color, foci hemorrhage partial edematous change. Histologically the had an extensive small tubular growth pattern often papillary fronds mainly composed oncocytic cells deeply...
Reported herein is a gastric leiomyosarcoma, which, nowadays, extremely rare. Attention was focused not only on pathological findings but also the histological basis of magnetic resonance imaging (MRI) findings. The patient 29‐year‐old Japanese woman. Preoperative T2‐weighted MRI showed large high‐intensity tumor with isointense streaks. broad‐based polypoid lesion and histologically consisted fascicles spindled cells having eosinophilic cytoplasm cigar‐shaped nuclei. Immunoreactivity for...
Safety measures concerning drunk driving are the major technical challenges in car industry. We have developed systems to prevent by applying our new, non-contact breath-alcohol sensor which original breath is coupled with an alcohol sensor. The detects measuring electric currents of positively or negatively charged water clusters that separated using field. Our simultaneously electrical signal and breath. This insures sample a person's breath, not artificial source.
For the purpose of application odor to information technology, we have developed an odor-emitting apparatus coupled with chemical capsules made alginic acid polymer. This consists a capsule cartridge including ingredients, valves control emission, and temperature unit. Different odors can be easily emitted by using apparatus. We integrated system vision, audio olfactory in which strength controlled coinciding on-screen moving images based on analytical results from scanner.