Koichi Okada

ORCID: 0000-0002-0338-4842
Publications
Citations
Views
---
Saved
---
About
Contact & Profiles
Research Areas
  • Prostate Cancer Treatment and Research
  • Advancements in Photolithography Techniques
  • Plasma and Flow Control in Aerodynamics
  • Urinary Bladder and Prostate Research
  • Prostate Cancer Diagnosis and Treatment
  • ZnO doping and properties
  • Bladder and Urothelial Cancer Treatments
  • Hormonal and reproductive studies
  • Urological Disorders and Treatments
  • T-cell and Retrovirus Studies
  • Urinary and Genital Oncology Studies
  • Fluid Dynamics and Turbulent Flows
  • Semiconductor materials and devices
  • Electron and X-Ray Spectroscopy Techniques
  • Testicular diseases and treatments
  • Multiferroics and related materials
  • Radiation Detection and Scintillator Technologies
  • Sperm and Testicular Function
  • Aerodynamics and Fluid Dynamics Research
  • Gas Sensing Nanomaterials and Sensors
  • Advanced Surface Polishing Techniques
  • Advanced Vision and Imaging
  • Multiple and Secondary Primary Cancers
  • Pelvic floor disorders treatments
  • Radioactive contamination and transfer

Osaka University
2012-2025

Sumitomo Hospital
2017-2024

Nara Medical University
2022-2023

Rakuwakai Otowa Hospital
2021

Ryoka Systems (Japan)
2013-2020

National Institute for Materials Science
2009-2017

Osaka Research Institute of Industrial Science and Technology
2011-2017

Saitama Medical University
1980-2016

Yamaguchi University
1996-2016

Population Council
2015-2016

Abstract Background The pathophysiology of the prostate enlargement underlying lower urinary tract symptoms is unknown. Meanwhile, gut microbiota can contribute to various host conditions. We hypothesized that plays a role in enlargement. Methods included 128 patients who underwent biopsies at our hospitals between December 2018 and March 2020, excluding those had used antibiotics within past 6 months were diagnosed with cancer cT3 or higher. Patients volumes ≥30 ml defined as...

10.1002/pros.24223 article EN The Prostate 2021-09-13

To evaluate the clinical usefulness of [18F]fluorodeoxyglucose positron emission tomography (FDG-PET) compared with histopathological grading, stage and serum prostatic specific antigen (PSA) level in detection characterization prostate cancer.Forty-four patients histologically proven cancer five control subjects benign hyperplasia (BPH) were prospectively investigated FDG-PET prior to treatment.By visual inspection, FDG accumulation was positive 28 (sensitivity 64%), whereas all negative...

10.1093/jjco/29.12.623 article EN Japanese Journal of Clinical Oncology 1999-12-01

We conduct large-eddy simulations of separated airfoil flows with control by a dielectric-barrier-discharge plasma actuator over wide range Reynolds numbers. The numbers based on the chord length (Re) are set at Re = 5.0 × 103, 1.0 104, 6.3 2.6 105, and 1.6 106. These cover most conditions used in previous studies separation actuator. burst frequency nondimensionalized freestream velocity (F+) is as computational parameter, effective actuation mechanisms each number condition investigated....

10.1063/1.5136072 article EN Physics of Fluids 2020-02-01

It has been postulated that tumors beyond a certain size are dependent on angiogenesis, which might also be related to distant metastasis. We therefore assessed the prognostic significance of tumor microvasculature in renal cell carcinoma.Tumor specimens from 84 patients with primary carcinoma were examined by immunohistochemical staining for factor VIII. Individual microvessels counted 200 x field overlying area highest neovacularization.The mean number metastases was significantly higher...

10.1111/j.1442-2042.1995.tb00445.x article EN International Journal of Urology 1995-07-01

A variety of insect species induce galls on host plants. Liquid chromatographic/tandem mass spectrometric analyses showed that a gall midge (Rhopalomyia yomogicola) induces Artemisia princeps contained high levels indole-3-acetic acid and cytokinins. The larvae also synthesized from tryptophan. Close observation tissue sections indicated the larval chamber was surrounded by layers cells having secondary cell walls with extensive lignin deposition, except for part constituted feeding...

10.1271/bbb.130406 article EN Bioscience Biotechnology and Biochemistry 2013-09-06

ABSTRACT Experimental resin composites with incorporated polytetrafluoroethylene (PTFE) particles were developed, which theoretically could improve the surface properties of materials, including inhibition bacterial adherence. To assess in relation to biofilm formation and detachment, 23.1% (wt/wt) linear PTFE (FL-30) cross-linked (FC-30) into pure composites. Pure plates without (F-0) used as control specimens. Sucrose-dependent Streptococcus mutans biofilms formed on specimen blocks inside...

10.1128/aem.02039-07 article EN Applied and Environmental Microbiology 2008-01-12

The purpose of this study was to evaluate the inhibition biofilm formation on newly developed coating materials with self-cleaning properties. A series experimental containing fluoroalkylated acrylic acid oligomer (FAAO) were applied resin composite substrates. surfaces analyzed by X-ray photoelectron spectroscopy (XPS) and contact angle measurement. Biofilm surface assessed using Streptococcus mutans biofilms inside an oral simulator in vitro. results indicated that increase concentration...

10.4012/dmj.27.565 article EN Dental Materials Journal 2008-01-01

Measurement of radioactive contamination and confirmation the decontamination effects are important for recovery from nuclear accident at Fukushima Dai-ichi Nuclear Power Plant.We have developed a gamma camera which can visualize gamma-ray intensity distribution in real time.Experiments were conducted to investigate its performance.An energy resolution 2.3 % spatial 0.68 m distance 5 confirmed.In addition, field tests Plant.The was successfully visualized within as short time 10 seconds an...

10.15669/pnst.4.14 article EN Progress in Nuclear Science and Technology 2014-01-01

Transparent films of Fe-doped indium tin oxide (ITO) were grown at oxygen pressures 5, 1, 10-1, 10-2, and 10-3 Pa on yttria-stabilized zirconia (001) substrates by a pulsed-laser deposition method. We observed X-ray diffraction peaks from (00h) planes In2O3 crystalline phase for the films. The 5 1 paramagnetic semiconducting, that 10-1 was ferromagnetic those 10-2 metallic. Fe-ITO below exhibited room-temperature (RT) ferromagnetism. Nanoscale Fe clusters in highest oxidation state such as...

10.1143/jjap.45.l957 article EN Japanese Journal of Applied Physics 2006-09-01

The authors have developed a new technique for preparing dental CAD/CAM composite resin blocks (CRBs): the filler press and monomer infiltration (FPMI) method. In this method, surface-treated is molded into green body in which particles are compressed to form an agglomeration. then infiltrated with mixture before being polymerized. It possible produce CRBs using method through densely packed nanofiller uniformly dispersed. greater pressure of molding, more CRB, resulting at high very dense...

10.4012/dmj.2013-329 article EN Dental Materials Journal 2014-01-01

Large-eddy simulations (LES) are employed to understand the flow field over a NACA 0015 airfoil controlled by dielectric barrier discharge (DBD) plasma actuator. The Suzen body force model is utilised introduce effect of DBD Reynolds number fixed at 63,000. Transient processes arising due non-dimensional excitation frequencies one and six discussed. time required establish authority between four characteristic times, independent frequency. If separation suppressed, initial conditions do not...

10.1080/10618562.2015.1032271 article EN International journal of computational fluid dynamics 2015-03-16

Abstract Purpose The average fatherhood age has been consistently increasing in developed countries. Aging identified as a risk factor for male infertility. However, its impact on various mechanisms remains unclear. This study focused the KEAP1–NRF2 oxidative stress response system, by investigating relationship between system and age‐related changes spermatogenesis. Method s For examination of changes, we used 10‐, 30‐, 60‐, 90‐week‐old mice to compare sperm count, motility, protein...

10.1002/rmb2.12595 article EN cc-by-nc-nd Reproductive Medicine and Biology 2024-01-01

This paper investigates the control of leading-edge flow separation over an airfoil using a dielectric-barrier discharge plasma actuator. A chord-based Reynolds number and angle attack are 18.8 deg, respectively. The around stalled is computed by large-eddy simulations. body-force distribution-based actuator model adopted set near leading edge airfoil. Effects nondimensional burst frequency with constant duty cycle on performance studied. It found that, for cases frequencies 5, 10, 25, 50,...

10.2514/1.j055727 article EN AIAA Journal 2017-07-14

To evaluate the clinical utility of transrectal power Doppler imaging (PDI) prostate for detecting cancer in patients with abnormally high serum levels specific antigen (PSA).Patients (107) PSA were assessed using a digital rectal examination (DRE), ultrasonography (TRUS) and PDI. Any hypervascular lesion on PDI was graded scale 0-3, where grade 1-3 considered positive 0 negative. Patients then diagnosed by prostatic needle biopsy results compared other detection methods.Needle confirmed 41...

10.1046/j.1464-410x.2000.00663.x article EN BJU International 2000-09-01

To isolate novel molecular targets for treatment of testicular germ cell tumor (TGCT), we performed genome‐wide expression profile analysis seminomas using a cDNA microarray. We here report identification NACHT, leucine‐rich repeat and PYD containing 7 ( NALP7 ), that was significantly transactivated in seminomas. Subsequent semi‐quantitative RT‐PCR northern blot analyses confirmed an approximately 3.3‐kb transcript expressed exclusively testis, although the level this gene normal testis...

10.1111/j.1349-7006.2004.tb03182.x article EN other-oa Cancer Science 2004-12-01

To identify new diagnostic markers for testicular germ cell tumors (TGCTs), including seminomas, as well potential targets of drugs treating the disease, we compared gene-expression profiles cancer cells from 13 seminomas with normal human testis using laser-capture microdissection and a cDNA microarray representing 23,040 genes. We identified 347 genes that were commonly up-regulated in seminoma cells. The functions 227 known to some extent; remaining 120 included 55 ESTs. On list cyclin D2...

10.3892/ijo.23.6.1615 article EN International Journal of Oncology 2003-12-01
Coming Soon ...