A5083815331- Motor Control and Adaptation
- Action Observation and Synchronization
- Tactile and Sensory Interactions
- Muscle activation and electromyography studies
- Neurology and Historical Studies
- Pain Management and Treatment
- EEG and Brain-Computer Interfaces
- Transcranial Magnetic Stimulation Studies
- Neural dynamics and brain function
- Musculoskeletal pain and rehabilitation
- Pain Mechanisms and Treatments
- Multisensory perception and integration
- Free Will and Agency
- Hereditary Neurological Disorders
- Facial Nerve Paralysis Treatment and Research
- Hearing Impairment and Communication
- Neurological disorders and treatments
- Psychosomatic Disorders and Their Treatments
- Hemispheric Asymmetry in Neuroscience
- Erythrocyte Function and Pathophysiology
- Functional Brain Connectivity Studies
- Spinal Cord Injury Research
- Balance, Gait, and Falls Prevention
- Neuroscience and Neural Engineering
- Neural and Behavioral Psychology Studies
Bournemouth University
2014-2024
University Hospitals Dorset NHS Foundation Trust
2024
Dorset HealthCare University NHS Foundation Trust
2024
Poole Hospital
2012-2023
Poole Hospital NHS Foundation Trust
2014-2017
University of Southampton
1996-2013
National Health Service
2013
Helsinki University Hospital
2009
University of Roehampton
2007
University of Louisville
2005
Objective Tactile spatial acuity is routinely tested in neurology to assess the state of dorsal column system. In contrast, for pain not assessed, having never been systematically characteri z ed. More than a century after initial description tactile across body, we provide first systematic whole‐body mapping pain. Methods We evaluated 2‐point discrimination thresholds both nociceptive‐selective and stimuli several skin regions. Thresholds were estimated using pairs simultaneous stimuli,...
Although the theoretical importance of perspective taking has long been recognized, surprisingly little work documented cognitions associated with attempts to imagine another's point view. To explore this issue and determine whether increases likelihood self-related thoughts, two experiments were carried out. In first, a thought-listing procedure was used assess observer cognitions; in second, less reactive measure used. Instructions self target's position instructions simply produced...
Purpose. Phantom limb pain is chronic and intractable. Recently, virtual reality (VR) motion capture technology has replicated the mirror box device of Ramachandran (Ramachandran et al. Nature 1995, 377, 489–490; Rogers-Ramachandran Proc R Soc Biol Sci 1996, 263, 377–386) led to reductions in this pain. We present results from a novel variation on method which captures data directly patient's stump (rather than using opposite remaining limb) then transforms it into goal directed, action...
1. Motor memory and the sense of effort have been investigated in a man with complete large fibre sensory neuropathy for over 16 years. The perceptions pain, heat, cold muscular fatigue remained but he was without light touch proprioception below neck. 2. subject able to discriminate weights held hand an accuracy only slightly worse than control subjects (20 g 200 g) when forearm movement visual inspection were allowed. With eyes shut however could distinguish weight from 400 g. It is...
Signals associated with the command brain sends to muscles are thought create sensation of heaviness when we lift an object. Thus, as a muscle is weakened by fatigue or partial paralysis (neuromuscular blockade), increase in motor needed weight explain increasing subjective lifted object.With different fatiguing contractions approximately halved force output thumb flexor muscles, which were then used For two deafferented subjects perceived object doubled, keeping central-signal theory....
The canonical view is that touch signaled by fast-conducting, thickly myelinated afferents, whereas pain slow-conducting, thinly ("fast" pain) or unmyelinated ("slow" afferents. While other mammals have afferents signaling (ultrafast nociceptors), these not been demonstrated in humans. Here, we performed single-unit axonal recordings (microneurography) from cutaneous mechanoreceptive healthy participants. We identified A-fiber high-threshold mechanoreceptors (A-HTMRs) were insensitive to...
In order to investigate the ways in which sensory channels interact control balance, we measured postural response evoked by galvanic vestibular stimulation (GVS) a rare subject (I. W.) with large-fibre neuronopathy. I. W. has no sensations of cutaneous light touch and movement/position sense below neck, without vision he knowledge where his limbs body are space. He was tested while seated. With eyes closed, W.'s responses pure stimuli were an magnitude larger than those healthy controls....
A well-substantiated, surprising finding is that people judge the occurrence of an event low probability as less likely when its represented by a ratio smaller (e.g., I in 20) than larger 10 200) numbers. The results three experiments demonstrated phenomenon broadly general and occurs readily pre-as post outcome judgments. These support interpretation terms subjective probability, suggested principles cognitive-experiential self theory, but not imagining counter-factual alternatives,...
There is a critical need for new analytics to personalize behavioral data analysis across different fields, including kinesiology, sports science, and neuroscience. Specifically, better translate integrate basic research into patient care, we radically transform the methods by which describe interpret movement data. Here, show that hidden in "noise," smoothed out averaging kinematics data, lies wealth of information selectively differentiates neurological mental disorders such as Parkinson's...
One hundred years ago, Erlanger and Gasser demonstrated that conduction velocity is correlated with the diameter of a peripheral nerve axon. Later, they also functional role axon related to its diameter: touch signalled by large-diameter axons, whereas pain temperature are small-diameter axons. Certain discoveries in recent decades prompt modification this canonical classification. Here, we review evidence for unmyelinated (C) fibres signalling at slow likely contributing affective aspects...
Abstract We present an investigation of facial expression recognition by three people (BC, LP, and NC) with Mobius syndrome, a congenital disorder producing paralysis. The participants were asked to identify the emotion displayed in 10 examples expressions associated each 6 basic emotions from Ekman Friesen (1976) series. None Möbius syndrome was significantly impaired on this task. On second test using computer-morphed expressions, NC showed statistically significant impairment, BC...
Human unmyelinated (C) tactile afferents signal the pleasantness of gentle skin stroking on hairy (nonglabrous) skin. After neuronal injury, that same type touch can elicit unpleasant sensations: allodynia. The prevailing pathophysiological explanation is a spinal cord sensitization, triggered by nerve which enables Aβ to access pain pathways. However, recent mouse knockout study demonstrates C-tactile are necessary for allodynia develop, suggesting role not only but also afferent signaling....