Takuya Nakamura

ORCID: 0000-0002-0342-0081
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About
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Research Areas
  • Linguistics and Discourse Analysis
  • Natural Language Processing Techniques
  • Historical Linguistics and Language Studies
  • French Language Learning Methods
  • Orthopaedic implants and arthroplasty
  • Total Knee Arthroplasty Outcomes
  • Botulinum Toxin and Related Neurological Disorders
  • Syntax, Semantics, Linguistic Variation
  • Hepatitis B Virus Studies
  • linguistics and terminology studies
  • Liver Disease Diagnosis and Treatment
  • Stroke Rehabilitation and Recovery
  • Hip disorders and treatments
  • Topic Modeling
  • Hepatitis C virus research
  • Orthopedic Infections and Treatments
  • NF-κB Signaling Pathways
  • Cerebral Palsy and Movement Disorders
  • Osteoarthritis Treatment and Mechanisms
  • Oral and Maxillofacial Pathology
  • Orthopedic Surgery and Rehabilitation
  • Elbow and Forearm Trauma Treatment
  • Bone Metabolism and Diseases
  • Hip and Femur Fractures
  • dental development and anomalies

Laboratoire d'Informatique Gaspard-Monge
2014-2024

Université Gustave Eiffel
2010-2024

Chiba-Nishi General Hospital
2024

Keio University
1999-2023

Yamagata City Hospital Saiseikan
2022-2023

Nagasaki University
2009-2023

Nara Medical University
2018-2022

Nara Medical University Hospital
2022

Toyama Prefectural Central Hospital
2001-2022

Murayama Medical Center
2019-2020

The functional anatomy of the triangular fibrocartilage complex (TFCC) was investigated in 20 fresh cadavers. Dynamic changes TFCC during rotation were also examined from both proximal and distal aspects. In our analysis, separated into three components. component stable, functioning like a hammock to suspend ulnar carpus. fan-shaped ligament, true radioulnar ligament. This found originate fovea ulna vertical fashion easily twisted rotation. third component, collateral When analysed by...

10.1016/s0266-7681(96)80135-5 article EN Journal of Hand Surgery (European Volume) 1996-10-01

Hepatitis B e antigen (HBeAg) constitutes the nucleocapsid of hepatitis virus (HBV) and occurs in association with plasma proteins, particularly IgG, serum persons infected virus. A polypeptide an approximate m.w. 15,500 (P15.5) is obtained either from HBeAg or HBV. P15.5 preparations resembled closely each other amino acid composition. The C-terminus sequence was determined to be -Thr-Thr-Val-Val, whereas that ended -Thr-Thr. same four residues found on gene coding for nucleopeptide a...

10.4049/jimmunol.130.6.2903 article EN The Journal of Immunology 1983-06-01

Background: Somatosensory impairment is common in patients who have had a stroke and can affect their motor function activities of daily living (ADL). Therefore, detecting treating somatosensory impairments properly considered to be very important, various examinations been developed. However, the reliability validity few them verified due differences procedure each examiner or poor quantification by examination itself. Objective: We hypothesized that, with fixed procedures two convenient...

10.3389/fneur.2020.625917 article EN cc-by Frontiers in Neurology 2021-01-27

Background and Purpose: Limited research has been conducted with the aim of understanding which upper extremity movements are difficult for persons severe chronic stroke. The purpose this study was to test structure Fugl-Meyer Assessment Upper Extremity (FMA-UE) using Rasch analysis in stroke moderate deficits determine item difficulty hierarchy. Methods: This a secondary data from previous randomized, controlled trials, or clinical trials. participants were 101 hemiparesis (time after onset...

10.3389/fneur.2020.577855 article EN cc-by Frontiers in Neurology 2020-11-16

ABSTRACT Objective To investigate the effectiveness of early and short-term administration lithium (Li) during orthodontic force application (OFA) in preventing orthodontically induced root resorption (OIRR) verify importance phase OFA induction OIRR. Materials Methods Bilateral maxillary first molars 10-week-old male Wistar rats were moved for 14 days using a closed coil spring inserted between molar incisor. The randomly grouped into three groups: group receiving Li 4 days, daily control...

10.2319/060324-433.1 article EN publisher-specific-oa The Angle Orthodontist 2025-02-06

Abstract We have developed a simple method for determination of 1,5-anhydro-D-glucitol in plasma, based on use pyranose oxidase (EC 1.1.3.10), an enzyme with specificity toward pyranoid compounds such as and glucose. Plasma samples deproteinized trichloroacetic acid are passed through two-layer mini-column packed strongly basic anion (OH- form, the upper layer) acidic cation (H+ lower exchange resins. 1,5-Anhydro-D-glucitol is efficiently recovered flow-through fraction, which almost devoid...

10.1093/clinchem/35.10.2039 article EN Clinical Chemistry 1989-10-01

Hepatitis B virus (HBV) infection is a worldwide health problem because of its potential to cause liver cirrhosis and hepatocellular carcinoma. Silibinin constituent an extract milk thistle, which empirically used as herbal medicine for the protection liver, but detailed effects on HBV are unknown. Because previous study reported that silibinin hinders clathlin-mediated endocytosis (CME), we aimed test whether inhibits entry into hepatocytes. Using HepG2-NTCP-C4 cells, overexpress sodium...

10.1016/j.bbrep.2018.03.003 article EN cc-by-nc-nd Biochemistry and Biophysics Reports 2018-03-31

A 4K2K 480 fps global-shutter CMOS image sensor has been developed with super 35 mm format. This employs newly gain-adaptive column ADCs to attain a dark random noise of 140 μV <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">rms</sub> for the full-scale readout 923 mV. An on-chip online correction error between two switchable gains maintains nonlinearity output within 0.18 %. The 16-channel interfaces 4.752 Gbps/ch are implemented in 2 diced...

10.1109/vlsic.2016.7573543 article EN 2016-06-01

The highly malignant phenotype of oral squamous cell carcinoma (OSCC), including the presence nodal and distant metastasis, reduces patient survival. High-mobility group A protein 2 (HMGA2) is a non-histone chromatin factor that involved in advanced phenotypes poor prognosis several human cancers. However, its biological role OSCC remains to be elucidated. purpose this study was determine clinical significance HMGA2 potential OSCC. We first investigated expression pattern relevance 110...

10.3390/ijms20102473 article EN International Journal of Molecular Sciences 2019-05-19

The authors examined early magnetic resonance images and histologic findings of avascular necrosis the femoral head in a canine model. model was surgically induced. Animals were euthanized at 3 days, 1, 2, 4 weeks, proximal femurs retrieved. Magnetic sections performed on each specimens obtained. Twenty-five mongrel dogs studied, days 7 other intervals. Findings suggest that changes may be seen as with marrow edema hemorrhage findings, fibrous transformation appositional bone growth later...

10.1097/00003086-199701000-00009 article EN Clinical Orthopaedics and Related Research 1997-01-01

Cylindromatosis (CYLD) is a tumor suppressor that regulates signaling pathways by acting as deubiquitinating enzyme. CYLDdown-regulation occurred in several malignancies, with tumor-promoting effects. Although we found loss of CYLD expression hypoxic regions human glioblastoma multiforme (GBM), the most aggressive brain tumor, biological roles GBM remain unknown. This study aimed to determine significance down-regulation progression and therapy. mRNA transcription was dramatically...

10.18632/oncotarget.2216 article EN Oncotarget 2014-07-14

This paper presents a 4K2K 480-fps global-shutter CMOS image sensor with super 35-mm format for highly realistic digital video system. The employs newly developed gain-adaptive column analog-to-digital converters to obtain input-referred dark random noise of 140 μ <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">Vrms</sub> an inputreferred full-scale readout 923 mV. An on-chip online correction the error between two switchable gains maintained...

10.1109/jssc.2016.2639741 article EN IEEE Journal of Solid-State Circuits 2017-01-09

Oral squamous cell carcinoma (OSCC) has a very poor prognosis because of its highly invasive nature, and the 5-year survival rate not changed appreciably for past 30 years. Although cylindromatosis (CYLD), deubiquitinating enzyme, is thought to be potent tumour suppressor, biological clinical significance in OSCC largely unknown. This study aimed clarify roles CYLD progression. Our immunohistochemical analyses revealed significantly reduced expression areas tissues, whereas was conserved...

10.1002/path.5019 article EN The Journal of Pathology 2017-12-13

Somatosensory function has been frequently overlooked in clinics and research the field of chronic stroke. The effects neurorehabilitation interventions on sensory processing have still to be investigated using electrophysiological means.This study effect hybrid assistive neuromuscular dynamic stimulation (HANDS) therapy utilizing closed-loop electromyography-controlled electrical (NMES), changes cortical plasticity among patients with stroke.This was a prespecified analysis 23 participants...

10.1177/2040622319889259 article EN cc-by-nc Therapeutic Advances in Chronic Disease 2019-01-01

// Takuya Nakamura 1,* , Satoru Shinriki 2,* Hirofumi Jono 3 Jianying Guo 4 Mitsuharu Ueda Mitsuhiro Hayashi 5 Satoshi Yamashita Andries Zijlstra 6 Hideki Nakayama 1 Akimitsu Hiraki Masanori Shinohara and Yukio Ando Department of Oral Maxillofacial Surgery, Graduate School Medical Sciences, Kumamoto University, Kumamoto, Japan 2 Laboratory Medicine, Clinical Pharmaceutical University Pharmacy, Hospital, Neurology, Breast Endocrine Pathology, Microbiology, Immunology, Vanderbilt Center,...

10.18632/oncotarget.2826 article EN Oncotarget 2014-11-25

Viruses are considered to use vesicular trafficking in infected cells, but the details of assembly/release pathways hepatitis B virus (HBV) still unknown. To identify key regulators HBV production, we performed short interfering RNA (siRNA) screening for Rab proteins, which act as molecular switches using HepG2.2.15 cells. Among 62 suppression Rab5B most significantly increased DNA culture supernatant. Surprisingly, 5 days after transfection siRNA, supernatant was more than 30-fold,...

10.1128/jvi.00621-19 article EN Journal of Virology 2019-05-22

Hepatitis B virus genotype (HBV/B) has been reported to have less risk of liver cirrhosis and hepatocellular carcinoma (HCC), but long-term observation rarely reported. We aimed clarify the characteristics HBV/B in nucleos(t)ide analog-treated patients an area where is more prevalent than other areas Japan.A total 498 chronically HBV-infected treated with analog (lamivudine, entecavir, tenofovir disoproxil fumarate, or alafenamide fumarate) for >6 months (mean 70.6 months) were included from...

10.1111/hepr.13398 article EN Hepatology Research 2019-06-29
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