Francisco António
- Hispanic-African Historical Relations
- Medicine and Dermatology Studies History
- Historical and socio-economic studies of Spain and related regions
- Occupational Health and Safety in Workplaces
- Transportation Planning and Optimization
- Business, Innovation, and Economy
- Infective Endocarditis Diagnosis and Management
- Social Sciences and Policies
- Historical Studies of Medieval Iberia
- Spanish Literature and Culture Studies
- Archaeological and Historical Studies
- Historical Studies on Spain
- Historical Art and Architecture Studies
- Urban Transport and Accessibility
- Religious and Theological Studies
- Early Modern Spanish Literature
- Regional Development and Innovation
- Aging, Health, and Disability
- Language, Linguistics, Cultural Analysis
- Criminal Justice and Penology
- Educational theories and practices
- Transportation and Mobility Innovations
- Education and Teacher Training
- Media, Journalism, and Communication History
- Sports and Physical Education Studies
University of Foggia
2025
Universidad de Zaragoza
2022-2024
Hospital Universitario Puerta de Hierro Majadahonda
2022-2024
Universidad Autónoma de Madrid
2024
Colciencias
2024
Universidad de Murcia
2024
Weatherford College
2024
National Polytechnic School
2023
Hospital Juan Ramón Jiménez
2023
Universidad de Antioquia
2022
Several aspects of the occurrence and management mycotic aneurysm (MA) in patients with infective endocarditis (IE) have not been studied. To determine incidence factors associated MA presence rupture to assess evolution those initially unruptured MA. Prospective multicenter cohort including all definite IE between January 2008 December 2020. Of 4548 cases, 85 (1.9%) developed Forty-six (54.1%) had intracranial 39 (45.9%) extracranial Rupture occurred (45.9%). Patients ruptured higher 1-year...
To determine whether chronic high-fructose feeding causes insulin resistance and hypertension in normal dogs, we fed 10 male dogs a normosodic diet containing 60% of the calories as fructose for 20 to 28 days; control group 8 was similar dextrose instead fructose. In fructose-fed group, (1) fasting triglyceridemia increased from 35.3 +/- 0.63 91.9 11.55 mg/dL after 25 days (P < .001); (2) insulinemia 19.0 1.9 58.9 7.22 microU/mL (3) resistance, which estimated by steady-state glycemia...
Abstract We studied mechanisms of resistance to the novel taxane cabazitaxel in established cellular models resistance. also developed cabazitaxel-resistant variants from MCF-7 breast cancer cells by stepwise selection drug alone (MCF-7/CTAX) or plus transport inhibitor PSC-833 (MCF-7/CTAX-P). Among multidrug-resistant (MDR) variants, was relatively less cross-resistant than paclitaxel and docetaxel (15- vs. 200-fold MES-SA/Dx5 9- 60-fold MCF-7/TxT50, respectively). MCF-7/TxTP50 that were...
Abstract Background Outpatient parenteral antibiotic treatment (OPAT) has proven efficacious for treating infective endocarditis (IE). However, the 2001 Infectious Diseases Society of America (IDSA) criteria OPAT in IE are very restrictive. We aimed to compare outcomes with those hospital-based (HBAT). Methods Retrospective analysis data from a multicenter, prospective cohort study 2000 consecutive patients 25 Spanish hospitals (2008–2012) was performed. Results A total 429 (21.5%) received...
Antiretroviral drugs with a lower potential to induce hepatic steatosis in human immunodeficiency virus (HIV) infection need be identified. We compared the effect of switching efavirenz (EFV) raltegravir (RAL) on among HIV-infected patients nonalcoholic fatty liver disease (NAFLD) receiving EFV plus 2 nucleoside analogues. tenofovir/emtricitabine or abacavir/lamivudine NAFLD were randomized 1:1 switch from RAL (400 mg twice daily), maintaining analogues unchanged, continue At baseline,...
El consumo de fresas contaminadas por norovirus humano (HuNoV) ha sido asociado a brotes gastroenteritis aguda. Los tratamientos no térmicos, como el procesado mediante altas presiones hidrostáticas (HPP), representan tecnologías capaces inactivar microrganismos patógenos y, además, preservar las propiedades organolépticas y sus productos derivados. estudio se centrado en evaluar efecto HPP modulando los parámetros operativos presión (350-450 MPa) tiempo (0-10 min) puré fresa inoculado con...
Journal Article International or French? The early Sanitary Conferences and France's struggle for hegemony in the mid-nineteenth century Mediterranean Get access Francisco Javier Martínez * author is a Marie Curie Postdoctoral Fellow at Laboratoire SPHERE, CNRS-Université Paris Diderot, 5 rue Thomas Mann, 75205 Cedex 13, France. He may be contacted franciscojavier_martinez@yahoo.com. This paper has been written with support of grant from Intra-European Fellowships Career Development (IEF)...
Evidence supporting combination treatment with a beta-lactam plus an aminoglycoside (C-BA) for endocarditis caused by viridans and gallolyticus group streptococci (VGS-GGS) intermediate susceptibility to penicillin (PENI-I) is lacking. We assessed the clinical characteristics outcomes of PEN-I VGS-GGS compared effectiveness safety C-BA third-generation cephalosporin monotherapy.Retrospective analysis prospectively collected data cohort definite penicillin-susceptible PENI-I (penicillin...
Abstract Background Patients who acquire infective endocarditis (IE) following contact with the healthcare system, but outside hospital, are classified as having non-nosocomial healthcare-associated IE (HCIE). Our aim was to characterize HCIE and establish whether its etiology, diagnosis, therapeutic approach suggest it should be considered a distinct entity. Methods This study retrospectively analyzes data from nationwide, multicenter, prospective cohort including consecutive cases of at 45...
Outpatient parenteral antibiotic treatment (OPAT) programs are increasingly used to manage infective endocarditis (IE), but current criteria for indicating OPAT markedly conservative. We aimed investigate whether more liberal in IE can be safely used.This was a prospective multicenter nationwide cohort study (2008-2018). Rates of readmission, recurrences, and 1-year mortality were compared between hospital-based (HBAT) OPAT. Risk factors readmission patients investigated by logistic...
With this article I intend to contribute the debate about how study urban life. Firstly, argue for relevance of invisible and silent aspects cities inbetween sutures, which understand mean a third ’something’ beyond forms flows. Secondly, explore several examples draw on arguments from Wittgenstein Lefebvre frame hypothesis. Thirdly, use chess game as metaphor illustrate multiplicity unpredictability engagements Finnally, propose approach in an open-ended ordinary way, paying attention...
Although Streptococcus anginosus group (SAG) endocarditis is considered a severe disease associated with abscess formation and embolic events, there limited evidence to support this assumption. We performed retrospective analysis of prospectively collected data from consecutive patients definite SAG in 28 centers Spain Italy. A comparison between cases due viridans streptococci (VGS) or gallolyticus (SGG) was 1:2 matched analysis. Of 5336 endocarditis, 72 (1.4%) were 144 VGS/SGG. community...
Poco se sabe sobre los usos y lecturas de las noticias electorales por parte votantes mexicanos. Los resultados esta encuesta telefónica muestreo en Monterrey, Nuevo León, discutidos desde la perspectiva estudios culturales, indican que esa ciudad consideraron objetiva, balanceada útil cobertura sus medios informativos campaña electoral a gubernatura del Estado León 2009.
Mural infective endocarditis (MIE) is a rare type of endovascular infection. We present comprehensive series patients with mural endocarditis.Patients infectious (IE) from 35 Spanish hospitals were prospectively included in the GAMES registry between 2008 and 2017. MIEs compared to non-MIEs. also performed literature search for cases MIE published 1979 2019 them GAMEs series.Twenty-seven out 3676 IEs included. When valvular IE (VIE) or device-associated (DIE), younger (median age 59 years, p...
Two patients suffering from idiopathic unilateral lower limb lymphedema were treated with a diet in which long-chain triglycerides (LCT) drastically restricted. From the beginning of treatment, distinct improvement was observed both patients, reduction affected perimeters, decrease edema tension, and skin turgescence. Patient A underwent weight loss, diameter greater than that nonaffected limb. In patient B, whose remained stable during study, remarkable diminution, while no changes detected...
Peroxisomicine A1 (T-514) is a dimeric anthracenone first isolated from the plant Karwinskia humboldtiana. The compound presents high and selective toxicity toward liver skin cell cultures currently subject of preclinical studies as an antitumor drug. To date, molecular basis for its diverse biological effects remains poorly understood. elucidate mechanism action, we studied interaction with DNA on human topoisomerases. Practically no was detected. found to inhibit topoisomerase II but not...
Tropheryma whipplei has been detected in 3.5% of the blood culture-negative cases endocarditis Spain. Experience management T. is limited. Here we report long-term outcome treatment previously reported patients who were diagnosed with infective (IE) caused by from Spanish Collaboration on Endocarditis-Grupo de Apoyo al Manejo la Endocarditis Infecciosa en España (GAMES) and discuss potential options for antimicrobial therapy IE whipplei. Seventeen recruited between 2008 2014 25 hospitals....