Víctor José González Ramallo
A5063819380- Infective Endocarditis Diagnosis and Management
- Historical Art and Architecture Studies
- Antimicrobial Resistance in Staphylococcus
- Antibiotics Pharmacokinetics and Efficacy
- Archaeological and Historical Studies
- Libraries, Manuscripts, and Books
- Historical Studies of Medieval Iberia
- Streptococcal Infections and Treatments
- Medieval and Early Modern Iberia
- Bacterial Identification and Susceptibility Testing
- Cardiac Valve Diseases and Treatments
- Medieval Architecture and Archaeology
- Nosocomial Infections in ICU
- Antibiotic Use and Resistance
- Spanish Literature and Culture Studies
- Orthopedic Infections and Treatments
- Sepsis Diagnosis and Treatment
- Historical Studies in Latin America
- Early Modern Spanish Literature
- History of Education in Spain
- Religious and Theological Studies
- Spanish History and Politics
- Cultural and Mythological Studies
- Forensic Toxicology and Drug Analysis
- Central Venous Catheters and Hemodialysis
Hospital General Universitario Gregorio Marañón
2015-2025
Hospital Universitario de Torrejón
2023
Centro de Investigación Biomédica en Red de Enfermedades Respiratorias
2019-2022
Universidad Complutense de Madrid
2014-2021
Duke University Hospital
2017
Duke Medical Center
2017
National Institute on Population Medical Genetics
2012
Universidade Federal do Rio Grande do Sul
2012
Frequency of enterococcal bloodstream infection (E-BSI) is increasing, and the number episodes complicated by infective endocarditis (IE) varies. Performing transesophageal echocardiography (TEE) in all patients with E-BSI costly time-consuming. Our objectives were to identify who are at very low risk IE (and therefore do not require TEE) compare outcome with/without IE.Between September 2003 October 2012, we performed a prospective cohort study (all E-BSI) case-control (patients IE) our...
Abstract Background Outpatient parenteral antibiotic treatment (OPAT) has proven efficacious for treating infective endocarditis (IE). However, the 2001 Infectious Diseases Society of America (IDSA) criteria OPAT in IE are very restrictive. We aimed to compare outcomes with those hospital-based (HBAT). Methods Retrospective analysis data from a multicenter, prospective cohort study 2000 consecutive patients 25 Spanish hospitals (2008–2012) was performed. Results A total 429 (21.5%) received...
The POET trial demonstrated that moving from intravenous to oral antibiotics in stable patients with left-sided infective endocarditis (IE) was noninferior fully parenteral treatment. However, it did not compare outpatient strategies. OraPAT-IE GAMES is a noninferiority, multicenter, randomized, open-label study aimed partial versus antibiotic therapy (OPAT) for consolidation of treatment IE. A total 342 IE caused by selected micro-organisms will eventually be included. After minimum 10 days...
Background. Infective endocarditis (IE) is a severe condition. Our aim was to describe the profile and prognosis of patients with multivalvular infective (MIE) compare them single-valve IE (SIE). Methods. We used retrospective analysis Spanish Registry (2008−2020). Results. From 4064 definite cases valvular IE, 577 (14.2%) had MIE. In MIE, most common locations were mitral (552, 95.7%) aortic (550, 95.3%), mitral-aortic involvement present in 507 (87.9%). The etiologies S. viridans (192,...
Aim: To evaluate outpatient parenteral antimicrobial therapy (OPAT) in the hospital-at-home (HaH) model, using data from a Spanish registry. Patients & methods: We describe episodes/characteristics of patients receiving OPAT. Results: Four thousand and five were included (mean age 66.2 years), generating 4416 HaH episodes, 4474 infections 5088 antibiotic treatments. Most hospital admission ward emergency department. Respiratory, urinary intra-abdominal predominated (72%). Forty-six different...
Infective endocarditis (IE) is a complex infection associated with high mortality. Daptomycin, cyclic lipopeptide antibiotic highly active against Gram-positive bacteria, has recently been incorporated into IE treatment guidelines. This retrospective analysis provides insights the use of daptomycin in European Cubicin® Outcomes Registry Experience (EU-CORESM) between 2006 and 2010. Three hundred seventy-eight (10%) 3621 enrolled patients received for IE. Two fifty-nine (69%) had left-sided...
A retrospective analysis of data from patients receiving daptomycin as outpatient parenteral antimicrobial therapy (OPAT) within the European Cubicin Outcomes Registry and Experience (EU-CORE(SM)) was performed. Of 4592 enrolled in 15 countries, 550 (12%) received OPAT. these, 149 (27%) without hospital admission, 84% had significant underlying diseases 44% were ≥65 years age. Most frequently treated infections complicated skin soft-tissue (28%), osteomyelitis (17%), foreign body/prosthetic...
ObjectivesEnterococcus spp. account for 10% of infective endocarditis (IE). Although daptomycin is a bactericidal drug with in vitro activity against Enterococcus, there little experience its use IE. We analysed the effectiveness treatment enterococcal IE (EIE).
The aim of this study was to evaluate the clinical outcomes and safety daptomycin therapy in patients with serious Gram-positive infections.Patients were enrolled European Cubicin(®) Outcomes Registry Experience (EU-CORE(SM)), a non-interventional, multicenter, observational registry. real-world data collected across 18 countries (Europe, Latin America, Asia) for who had received at least one dose between January 2006 April 2012. Two-year follow-up until 2014 endocarditis,...
BACKGROUNDCândido Godói (CG) is a small town in South Brazil, which has the highest prevalence of twin births Brazil. Recently, number studies have shown that p53 plays an important role reproduction through blastocyst implantation and intra utero embryo survival. Thus, gene polymorphisms pathway were investigated this population.
Outpatient parenteral antibiotic treatment (OPAT) programs are increasingly used to manage infective endocarditis (IE), but current criteria for indicating OPAT markedly conservative. We aimed investigate whether more liberal in IE can be safely used.This was a prospective multicenter nationwide cohort study (2008-2018). Rates of readmission, recurrences, and 1-year mortality were compared between hospital-based (HBAT) OPAT. Risk factors readmission patients investigated by logistic...
Daptomycin is an optimal choice for outpatient parenteral antibiotic therapy (OPAT) because of its safety, once-daily administration and activity against Gram-positive bacteria. Although daptomycin increasingly being used in OPAT, limited information about safety this scenario available.We performed a prospective multicentre pilot study to evaluate the outpatients with proved or suspected infections (DAPTODOM). The primary objective was secondary efficacy OPAT. We also looked at development...