In this review, we survey the diversity of structures and functions which are encountered in advanced self-assembled nanomaterials. We highlight their flourishing implementations three active domains applications: biomedical sciences, information technologies, environmental sciences. Our main objective is to provide reader with a concise straightforward entry broad field by selecting most recent important research articles, supported some more comprehensive reviews introduce each topic....

Pumping iron: Double-threaded rotaxanes can be linked to coordination units and polymerized in the presence of iron or zinc ions. pH modulation triggers cooperative contractions (or extensions) individual rotaxanes, thus resulting an amplified motion muscle-like supramolecular chains with changes their contour lengths several micrometers (see picture).

A concise and convergent total synthesis of the highly cytotoxic marine natural products iejimalide A−D (1−4) is reported, which relies on an effective ring-closing metathesis (RCM) reaction a cyclization precursor containing no less than 10 double bonds. Because exceptional sensitivity this polyunsaturated intermediate its immediate precursors toward acid, base, even gentle warming, assembly process hinged upon judicious choice protecting groups careful optimization all individual...

The implementation of artificial molecular machines in polymer science is an important objective that challenges chemists and physicists order to access entirely new class smart materials. To design such systems, the amplification a mechanical actuation from nanoscale up macroscopic response bulk material central issue. In this article we show bistable [c2]daisy chain rotaxanes (i.e., muscles) can be linked into main-chain Upy-based supramolecular polymers. We then reveal by depth...

Triarylamine molecules and triarylamine-based covalent polymers have been extensively investigated for more than 60 years in academics industry because of their intriguing electronic optical characteristics. However, despite the profusion studies made on these derivatives, only very recently first examples supramolecular based triarylamine motif described literature. Specifically, our research group has shown that, by adding supplementary hydrogen bonding moieties such as amide functions...

The implementation of molecular machines in polymer science is high interest to transfer mechanical motions from nanoscale macroscale order access new kinds active devices and materials. Toward this objective, thermodynamic topological aspects need be explored for reaching efficient systems capable producing a useful work. In paper we describe the branched polymerization pH-sensitive bistable [c2] daisy chain rotaxanes by using copper(I)-catalyzed Huisgen 1,3-dipolar cycloaddition ("click...

Organic materials exhibiting metallic behavior are promising for numerous applications ranging from printed nanocircuits to large area electronics. However, the optimization of electronic conduction in organic metals such as charge-transfer salts or doped conjugated polymers requires high crystallinity, which is detrimental their processability. To overcome this problem, combination properties metal-like with mechanical soft self-assembled systems attractive but necessitates absence...

Open AccessCCS ChemistryMINI REVIEW1 Apr 2019[c2]Daisy Chain Rotaxanes as Molecular Muscles Antoine Goujon, Emilie Moulin, Gad Fuks and Nicolas Giuseppone Goujon SAMS Research Group, Institut Charles Sadron, CNRS, University of Strasbourg BP 84047, cedex 2 (France) , Moulin *Corresponding author: E-mail Address: [email protected] https://doi.org/10.31635/ccschem.019.20180023 SectionsAboutAbstractPDF ToolsAdd to favoritesDownload CitationsTrack Citations ShareFacebookTwitterLinked InEmail...

A hydrophobic light-driven rotary motor is functionalized with two 18-crown-6 macrocycles and incorporated into phospholipid bilayers. In the presence of this molecular construct, fluorescence assays patch clamp experiments show formation selective alkali ion channels through membrane. Further, they reveal a strongly accelerated transport mechanism under light irradiation. This increase fractional activity (up to 400%) attributed out-of-equilibrium actuation dynamics motors, which help...

A unidirectional light-driven rotary motor was looped in a figure-of-eight molecule by linking two polymer chains between its stator and rotor parts. By properly tuning the size of these linkers, clockwise rotation under UV light shown to create conformationally strained twists chains, this tensed conformation, energy stored molecular object sufficient trigger reverse back fully relaxed state. The functioning principle motorized device appears very similar that macroscopic whirligig crafts...

Let there be more light: Triarylamine-based building blocks respond to visible-light exposure by the formation of cationic radicals that hierarchically self-assemble into molecular wires, which in turn combine within larger fibers (see picture). The stimuli-responsive supramolecular scaffold, is created charge transfer and reversibly broken up heating, prevents quenching holes wires.

The molecular chaperone HSP90 is an attractive target for chemotherapy because its activity required the functional maturation of a number oncogenes. Among know inhibitors, radicicol, 14-member macrolide, stands out as most potent. A dynamics/minimization radicicol showed that there were three low energy conformers macrocycle. lowest these bioactive conformation observed in cocrystal structure with HSP90. Corresponding conformational analyses several known analogues gave good correlation...

Triarylamine molecules appended with crown-ethers or carboxylic moieties form self-assembled supramolecular channels within lipid bilayers. Fluorescence assays and voltage clamp studies reveal that the self-assemblies incorporating crown ethers work as single for selective transport of K+ Rb+. The X-ray crystallographic structures confirm mutual columnar self-assembly triarylamines crown-ethers. dimensional fit cations 18-crown-6 leads to a partial dehydration formation alternating...

Abstract An acid–base switchable [ c 2]daisy chain rotaxane terminated with two 2,6‐diacetylamino pyridine units has been self‐assembled a bis(uracil) linker. The complementary hydrogen‐bond recognition patterns, together lateral van der Waals aggregations, result in the hierarchical formation of unidimensional supramolecular polymers associated bundles muscle‐like fibers. Microscopic and scattering techniques reveal that mesoscopic structure these depends on extended or contracted states...

The study of supramolecular polymers in the bulk, diluted solution, and at solid-liquid interface has recently become a major topic interest, going from fundamental aspects to applications materials science. However, examples liquid-liquid are mostly unexplored. Here, we describe polymerization triarylamine molecules their light-triggered organization chloroform-water interface. resulting interfacial nematic layer these 1D is further used as template for precise alignment spherical gold...

A S6-symmetric triarylamine-based macrocycle (i.e., hexaaza[16]paracyclophane), decorated with six lateral amide functions, is synthesized by a convergent and modular strategy. This shown to undergo supramolecular polymerization in o-dichlorobenzene, its nanotubular structure elucidated combination of spectroscopy microscopy techniques, together X-ray scattering molecular modeling. Upon sequential oxidation, spectroelectrochemical analysis the polymer suggests an extended electronic...

Abstract Iejimalide B ( 2 ) is the most promising member of a small family marine polyene macrolides endowed with remarkably selective activity against human cancer cell lines. As this product, however, hardly available from natural sources, detailed evaluation requires development an efficient and practical synthetic approach. This challenge has now been met by adapting first total synthesis previously reported our group to needs high material throughput. Redesigning access routes five...

By using a combination of experimental and theoretical tools, we elucidate unique physical characteristics supramolecular triarylamine nanowires (STANWs), their packed structure, as well the entire kinetics associated radical-controlled polymerization process. AFM, small-angle X-ray scattering, all-atomic computer modeling reveal two-columnar "snowflake" internal structure fibers involving π-stacking triarylamines with alternating handedness. The process triarylammonium radicals formation...