A5101701592- Random lasers and scattering media
- Photonic Crystals and Applications
- Silk-based biomaterials and applications
- Plasmonic and Surface Plasmon Research
- Gold and Silver Nanoparticles Synthesis and Applications
- Orbital Angular Momentum in Optics
- Photonic and Optical Devices
- Optical Coatings and Gratings
- Advanced biosensing and bioanalysis techniques
- Physical Unclonable Functions (PUFs) and Hardware Security
- Spectroscopy and Quantum Chemical Studies
- Quantum optics and atomic interactions
- Bariatric Surgery and Outcomes
- Electrospun Nanofibers in Biomedical Applications
- Skin Protection and Aging
- Integrated Circuits and Semiconductor Failure Analysis
- Nanofabrication and Lithography Techniques
- Photochromic and Fluorescence Chemistry
- Extracellular vesicles in disease
- Terahertz technology and applications
- Cephalopods and Marine Biology
- Spectroscopy Techniques in Biomedical and Chemical Research
- Corneal Surgery and Treatments
- Biosensors and Analytical Detection
- Quantum Dots Synthesis And Properties
Yonsei University
2013-2025
Seoul National University
2009-2024
Korea Electronics Technology Institute
2024
University of Ulsan
2019
Purdue University West Lafayette
2010-2018
Gangnam Severance Hospital
2013-2018
Dong-A Pharmaceutical (South Korea)
2011
Korea Advanced Institute of Science and Technology
2002
Taking advantage of the high impermeability property graphene and sharp surface plasmon resonance (SPR) curve silver, we numerically demonstrate that SPR imaging biosensors with a graphene-on-silver substrate can be used to achieve dramatically sensitivity as well prevent silver oxidation. Results our numerical study show few layers significantly increase sensitivity, compared conventional gold-film-based biosensor. In particular, single layered deposited on 60-nm thick film amplifies signal...
Abstract Counterfeit medicines are a fundamental security problem. Counterfeiting medication poses tremendous threat to patient safety, public health, and the economy in developed less countries. Current solutions often vulnerable due limited levels. We propose that highest protection against counterfeit would be combination of physically unclonable function (PUF) with on-dose authentication. A PUF can provide digital fingerprint multiple pairs input challenges output responses. On-dose...
Two different growth factors were physically and chemically loaded into a single nanofibrous matrix to increase wound healing efficacy obtain bi-phasic release profiles of the factors. Amine-functionalized block copolymers composed PCL PEG synthesized subsequently co-electrospun with bFGF solution prepare coaxial meshes. The meshes modified an EGF by conjugating surface-exposed amine groups nanofibers carboxylate EGF. characterization core-encapsulated surface-immobilized X-ray photoelectron...
Abstract Light in biological media is known as freely diffusing because interference negligible. Here, we show Anderson light localization quasi-two-dimensional protein nanostructures produced by silkworms ( Bombyx mori ). For transmission channels native silk, the flux governed a few localized modes. Relative spatial fluctuations quantities are proximal to regime. The sizes of passive cavities (smaller than single fibre) and statistics modes (decomposed from excitation at gain–loss...
Plasmonics has brought revolutionary advances to laser science by enabling deeply subwavelength nanolasers through surface plasmon amplification. However, the impact of plasmonics on other promising systems so far remained elusive. Here, we present a class random lasers enabled three-dimensional plasmonic nanorod metamaterials. While dense metallic nanostructures are usually detrimental performance due absorption losses, here lasing threshold keeps decreasing as volume fraction metal is...
Waste from non-degradable packaging materials poses a serious environmental risk and has led to interest in developing sustainable bio-based materials. Sustainable have been made diverse naturally derived such as bamboo, sugarcane, corn starch. In this study, we film using chitosan extracted the biomass of yellow mealworm (
Various ABA-type tri-block copolymers composed of poly(L-lactide) (PLA) or poly (lactide-co-glycolide) (PLGA) as the side A block and poly(epsilon-caprolactone) (PCL) middle B were synthesized to produce rapidly degrading elastic matrices useful for tissue engineering scaffolds. The terminal di-hydroxyl groups in PCL-diol (MW 2000) used initiator ring-opening polymerization L-lactide D,L-lactide glycolide, employing stannous octoate a catalyst. series by varying chain length monomer...
We demonstrate that the unique characteristics of random lasing in bone can be used to assess nanoscale structural alterations as a mechanical or biosensor, given is partially disordered biological nanostructure. In this proof-of-concept study, we conduct photoluminescence experiments on cortical specimens are loaded tension under testing. The ultra-high sensitivity, large detection area, and simple scheme lasers allow us detect prefailure damage at very small strains before any microscale...
A surface plasmon resonance (SPR) imaging biosensor based on silver substrates was investigated to demonstrate that could be used as a substrate material for sensitive detection of biomolecular interactions, despite its poor chemical stability. The calculation results showed oxidation film may lead decrease in the sensitivity due variation SPR characteristics such broader curve width and shallower minimum reflectance at resonance. effect change refractive index target analytes also explored....
Abstract Lithium metal anodes (LMAs) are regarded as a highly promising candidate for next‐generation batteries owing to their exceptional energy density. Nevertheless, the instability of interphase poses significant safety and degradation challenges LMAs, thereby impeding feasibility commercial application. Herein, based on lessons learned from stable solid‐electrolyte‐interface (SEI) layer formed with ethylene carbonate (EC) solvents graphite anodes, effects cyclic‐ethers systematically...
This study developed a sustainable colorimetric pH sensor using chitosan derived from mealworm (Tenebrio molitor) biomass and anthocyanin extracted red cabbage (Brassica oleracea). Chitosan was used as the substrate material, served indicator dye, collectively forming basis of sensor. The resulting pH-responsive film effectively measures levels 1 to 13, with distinct color shift pink green. demonstrated remarkable stability, maintaining fidelity after prolonged exposure aqueous environments,...
Abstract Background Dementia is associated with older adults; however, it can also affect younger individuals, known as young-onset dementia (YOD), when diagnosed before the age of 65 years. We aimed to conduct a retrospective cohort study involving middle-aged women investigate association between premorbid depression and YOD development. Methods included 1.6 million aged 40–60 years who underwent health checkups under Korean National Health Insurance Service investigated YOD. Results Women...
The emergence of metamaterials has presented an unprecedented platform to control the fundamental properties light at nanoscale. Conventional metamaterials, however, possess passive that cannot be modulated post-fabrication, limiting their application spectrum. Recent metasurface research explored a plethora active mechanisms modulate optical metasurfaces post-fabrication. A key mechanism involves use mechanical deformation, aided by deformable polymeric substrates. substrates enables...
Fluorescent proteins often result in phototoxicity and cytotoxicity, particular because some red fluorescent (RFP) produce release reactive oxygen species (ROS). The photogeneration of ROS is considered as a detrimental side effect cellular imaging or proactively utilized for ablating cancerous tissue. As ancient textiles biomaterials, silk produced by silkworms can directly be used fabrics processed into materials structures to host other functional nanomaterials. We report that transgenic...
Abstract Structural arrangement and dimension play vital roles in wave transport amplification as they can restrict the volume explored by waves. However, it is challenging to systematically investigate interplay among structural, optical, mechanical properties, part because of limited experimental platforms that modulate structural a continuous manner. We present light action Rhodamine B doped silk fibroin (SF) nanofibrous scaffolds its modulation via control alignment or directionality SF...
Anemia associated with intestinal parasites and malnutrition is the leading cause of morbidity mortality in small ruminants worldwide. Qualitative scoring conjunctival redness has been developed so that farmers can gauge anemia sheep goats to identify animals require treatment. For clinically relevant diagnosis, complete blood count-comparable quantitative methods often rely on complicated expensive optical instruments, requiring detailed spectral information hemoglobin. We report...
In this study, we investigated the enhanced sensing performance of a localized surface plasmon resonance (LSPR) biosensor by employing metal-dielectric double-layered subwavelength grating structures. The numerical results showed that LSPR substrate with dielectric spacer can provide not only better sensitivity but also significantly improved reflectance characteristic. While presence metallic gratings leads to broad and shallow curve inevitably, prevent propagating plasmons from being...
In this study, surface-enhanced Raman scattering (SERS) scheme is combined with localized surface plasmon resonance (LSPR) detection on a thin gold film stripe patterns of nanoparticles (GNPs) via convective self-assembly (CSA) method. The potential dual modal plasmonic substrates was evaluated by binding 4-ABT and IgG analytes, respectively. SERS experiments presented not only high sensitivity limit 4.7 nM an enhancement factor 1.34 × 10 5 , but excellent reproducibility relative standard...
We report that nacre (also known as mother-of-pearl), a wondrous nanocomposite found in nature, is rich photonic nanomaterial allowing the experimental realization of collective excitation and light amplification via coupled states. Localized modes three-dimensional complex media are typically isolated frequency space. However, multiple local resonances can be hybridized multilayered nanostructures so effective cavity size for efficient disordered resonators scaled up. states overlapped with...
A transmission-type surface plasmon resonance configuration with dielectric gratings regularly patterned on a silver film was investigated the aim of enhancing diffraction efficiency radiative plasmons. The theoretical work conducted using rigorous coupled-wave analysis in terms first order and conversion (CE). results show that pyramid can produce higher transmittance compared other grating profiles. Design optimization at wide range thicknesses periods resulted maximum larger than 77% peak...
Plasmon-enhanced fluorescence is attributable to two independent processes: 1) excitation enhancement due an increased electric field near metallic nanostructures and 2) emission from a surface plasmon resonance-coupled excited state of fluorophores. Using semiconductor nanocrystals (quantum dots) on disordered plasmonic mesoscopic imaging approach, we demonstrate that can diminish the efficiency. Thus, our experimental evidence this competitive behavior has critical implications for better...
We numerically demonstrate that alterations in random lasing modes can serve as a highly sensitive biosensing mechanism for single-nanoparticle quantitation. In our approach, subtle perturbations from single nanoparticle induce dramatic changes multiple eigenmodes disordered structures be detected by spectral variations of emission peaks. Several resonance mode frequencies show relatively linear responses to nanoscale perturbations, and each possess different levels perturbation sensitivity....