The COVID-19 outbreak seriously affected all economies, especially the operations of listed companies, around world. This article studies impact on firm-level cash holdings using difference-in-differences method. It finds that has a significant positive in serious-impact industries. Goodwill and goodwill impairment can weaken this impact, which may be related to higher business risks these firms. Therefore, managers should raise firms' holding level during pandemic protect firms against...

Purposes: To investigate whether valproic acid (VPA) has a neuroprotective effect against ischemia/reperfusion (I/R) injury in the rat retina, and to elucidate potential antioxidant mechanisms involved.Methods: Adult male Wistar rats were randomly divided into four groups: sham (group A), plus VPA B), I/R vehicle C), D). Retinal was produced by inducing an exceedingly high intraocular pressure (IOP). Prior insult, administered subcutaneously (300 mg/kg twice daily) for 7 days, after which...

Diabetic retinopathy (DR) is a serious diabetic complication caused by both environmental and genetic factors. Molecular mechanisms of DR may lead to the discovery reliable prognostic indicators. The current study aimed clarify mechanism microRNA-183 (miR-183) in relation PI3K/Akt/VEGF signaling pathway. Microarray-based gene expression profiling was used identify differentially expressed genes. Sprague-Dawley rats were for establishment models, then miR-183 altered mimic or inhibitor BTG1...

Proliferative diabetic retinopathy, the primary cause of vision loss in adults, is one serious microvascular complications caused by diabetes. Both poly-ADP-ribose-polymerase (PARP) and nuclear factor (NF)-κB signaling are involved injury process. Injury activates PARP, which turn potentiates NF-κB activation causes cell apoptosis. Like pathway, Notch1 plays a key role regulation proliferation, differentiation, However, connections between these pathways not well understood. In this study,...

Purpose: To identify the spectral domain optical coherence tomography predictors of visual prognosis in retinal vein occlusion macular edema after intravitreal conbercept injection. Methods: Retrospective cohort study 63 treatment-naive eyes received pro re nata with at least 3 months follow-up. The best-corrected acuity (BCVA) and scans were recorded baseline, 1 month, starting therapy. On tomography, following lesions 1-mm-wide area centered on fovea: disorganization inner layer extent,...

Fungal keratitis is a relatively common ocular disease requiring positive medical management combined with surgical intervention. Interleukin-17 (IL-17) was reported to promote the activation and mobilization of neutrophile granulocyte foci inflammation. This study investigated effect IL-17 production from Th17 cells on progression fungal keratitis. A mouse model induced by Candida albicans successfully constructed detect infiltration inflammatory in corneal tissues hematoxylin-eosin (HE)...

This study used optical coherence tomography scanning and 3D reconstruction of the macular region in high myopia to examine more thoroughly carefully differences between myopia-related complications with without dome-shape macula (DSM) determine whether DSM's fine structure has an effect on them.

Abstract Background To evaluate the etiology of lacrimal canalicular laceration and explore possible risk factors influencing prognosis. Methods The data 142 patients (142 eyes) with lacerations who were surgically treated using anastomosis combined bicanalicular stent intubation between March 2017 2018 reviewed. analyzed contained demographic information, types trauma, injury locations, associated additional ocular injuries, surgical outcomes at follow-up. main outcome measures anatomic...

SIGNIFICANCE Pregnancy-induced hypertension is a unique yet common complication in pregnant women and may cause retinopathy. Optical coherence tomography (OCT) help find the features of retinopathy that are difficult to observe through fundus examination. Not all patients can fully recover from PURPOSE This report describes case pregnancy-induced with represents OCT fluorescein angiography. CASE REPORT A 29-year-old woman presented bilateral blurred vision xanthopsia 2 days before her...

This study aimed to investigate the effects and mechanisms of water-soluble Semen cassiae polysaccharide (SCP) on retinitis pigmentosa (RP) in rats. One hundred rats were randomly divided into control, model, 50, 100 200 mg/kg SCP groups. The groups treated with for 5 days, respectively. On sixth day, N-nitroso-N-methylurea (MNU). After 12 h electroretinogram, retinal thickness, apoptosis photoreceptor cells, expressions related protein retina tissue determined. Results showed that, after...

Spectral domain optical coherence tomography (SD-OCT) is proposed as a way of predicting the development and likelihood retinal astrocytic hamartoma (RAH) in tuberous sclerosis complex (TSC) elderly patients. This report describes case RAH TSC an patient. The patient was 62-year-old woman experienced pain lower left abdomen for two years. Bilateral renal angiomyolipoma, multiple hepatic angiomyolipoma pulmonary nodules were demonstrated using computed (CT). Brain CT showed bilateral...

Social employment opportunities are increasing from the perspective of sustainable development, but conditions more detailed and strict. Therefore, this article studies challenges faced by management development. The relationship between development is analysed to determine significance research By analysing trends different groups people current situation management, it determined that include industrial restructuring, increased entrepreneurial opportunities, a flexible situation. gradual...

Posterior scleritis is a rare inflammatory ocular disease, characterized by severe and painful inflammation of the sclera. It often misdiagnosed or underdiagnosed, due to its general varying clinical presentation profile, which primarily involves pain visual impairment but can include eyelid edema, choroidal folds, serous retinal detachment, disc hard exudates in fovea subretinal mass. We report here case posterior scleritis, with symptoms eye red eye, initially as acute conjunctivitis.A...

Infectious keratitis is one of the leading causes irreversible vision loss.With emergence multidrug-resistant pathogen, despite appropriate diagnosis and antimicrobial treatment, infectious can still result in corneal opacity even melting perforation.Therefore, it imperative to develop novel treatment for keratitis.More recently, several articles have demonstrated effectiveness collagen cross-linking (CXL) treating via direct activity inhibition enzymatic degradation.In order highlight use...

Central serous chorioretinopathy (CSC) is a common retinal disease that causes vision loss worldwide. Studying the imaging characteristics of CSC helpful for differential diagnosis diseases. This study analyzed differences between acute and chronic provide related information.The aim this was to describe optical coherence tomography features in patients with CSC.Sixty-two eyes 56 were included study. Optical performed observe image features. The photoreceptor outer-segment (PROS) thickness...