Abstract The aim of this study was to evaluate the distribution new Corneal Visualisation Scheimpflug Technology (Corvis ST) parameters in normal, Post-laser situ keratomileusis (LASIK), Post-LASIK keratectasia (KE) and keratoconus (KC) eyes, explore diagnostic ability these distinguishing KE from LASIK eyes. Twenty-three normal 23 eyes KC were recruited study. following Corvis ST measured: Max Inverse Radius, deformation amplitude (DA) Ratio [2 mm], Pachy Slope, DA [1 Ambrosio’s relational...

Purpose . To investigate the effect of preoperative treatment and postoperative enhanced anti-inflammatory on alleviating meibomian gland dysfunction (MGD) dry eye induced by cataract surgery. Design Prospective, randomized clinical trial. Methods A total 120 patients with moderate obstructive-MGD were enrolled 60:30:30 number in cohorts I, II, III, respectively: Cohort I: routine treatment; II: (warming compress, lid hygiene, treatment) III: treatment. Main Outcomes Measures All...

Purpose: To identify the spectral domain optical coherence tomography predictors of visual prognosis in retinal vein occlusion macular edema after intravitreal conbercept injection. Methods: Retrospective cohort study 63 treatment-naive eyes received pro re nata with at least 3 months follow-up. The best-corrected acuity (BCVA) and scans were recorded baseline, 1 month, starting therapy. On tomography, following lesions 1-mm-wide area centered on fovea: disorganization inner layer extent,...

Objective . To evaluate the therapeutic effect of big bubble deep anterior lamellar keratoplasty (DALK) in patients with fungal keratitis. Methods Consecutive who had DALK for keratitis at Shandong Eye Hospital between July 2011 and December 2012 were included. In all patients, infiltration depth was more than 4/5ths corneal thickness. surgery performed bare Descemet membrane (DM) using technique. Corrected distance visual acuity (CDVA), graft status, intraoperative postoperative...

To investigate the mechanism of superficial stromal scarring in advanced keratoconus using confocal microscopy, keratocyte density, distribution, micromorphology corneal stroma, and SNP three groups were observed. Eight buttons examined by immunohistochemistry. The densities sub-Bowman’s anterior posterior stroma mean density significantly different among groups. In mild-to-moderate group, activated nuclei comparatively highly reflective ECM seen while fibrotic structures with high...

Purpose . To investigate the pachymetry distribution of central cornea and morphologic changes in subclinical keratoconus with normal biomechanics determine their potential benefit for screening very early keratoconus. Methods This retrospective comparative study was performed 33 clinically unaffected eyes topography from patients asymmetric ectasia (VAE-NTB; Corvis Biomechanical Index defined) 70 truly age-matched subjects. Corneal topographic, tomographic, biomechanical metrics were...

To compare the clinical and microstructural changes induced by different transepithelial iontophoresis-assisted corneal cross-linking (I-CXL) methods for keratoconus.A total of 42 eyes patients with progressive keratoconus were divided into two groups. Group A received I-CXL 5min, while group B 10min. Visual acuity, optical coherence tomography (OCT), specular microscopy confocal evaluated preoperatively at 1, 3, 6, 12mo postoperatively.Twelve months after operation, uncorrected visual...

To evaluate the changes of keratocytes and dendritic cells in central clear graft by laser scanning vivo confocal microscopy after penetrating keratoplasty (PK).Thirty adult subjects receiving PK at Shandong Eye Institute with grafts no sign immune rejection surgery were recruited into this study, 10 healthy adults controls. The evaluated microscopy, as well epithelium cells, keratocytes, corneal endothelium nerves (especially subepithelial plexus nerves).Median density nerves, keratocyte...

Abstract Early detection of keratoconus is a crucial factor in monitoring its progression and making the decision to perform refractive surgery. The aim this study was use tree technique classification prediction subclinical (SKC). A total 194 eyes (including 105 normal 89 with SKC) were included double-center retrospective study. Data separately used for training validation databases. baseline variables derived from tomography biomechanical imaging. models generated using Chi-square...

(1) Background: To analyze the indications, graft survival, and failure-related risk factors of repeat penetrating keratoplasty (RPK) in children. (2) Methods: In this case series, children younger than 12 years who received RPK at Beijing Tongren Hospital were reviewed. The indications for RPK, postoperative complications, survival analyzed. analysis potential variables associated with was performed using Cox proportional hazards regression. (3) Results: A total 30 eyes 29 included study....

Abstract Background To report an unusual case of salzmann nodular degeneration (SND) in posterior keratoconus (PKC) after a corneal penetrating injury. Case presentation A 56-year-old woman presented with history recurrent light sensitivity, foreign body sensation, and tears injury 20 years ago. The patient was diagnosed SND accompanying PKC by slit-lamp microscope, anterior segment optical coherence tomography (OCT), tomography. combined therapy medication (0.1% sodium hyaluronate eye...

Objective To observe the morphological characteristics of corneal topography in patients with keratoconus using ALLEGRO Oculyzer for measurements; to provide data early diagnosis and screening an analysis pathogenesis keratoconus.Methods This was a retrospective case control study.Sixty-two clinical (66 eyes),57 subclinical (57 eyes) 35 healthy people (70 were enrolled this research.All them examined measurements.Posterior surface classifications elevation divided into 6...

Objective To analyze the difference in corneal topography between primary keratoconus and secondary after LASIK;to provide a reference for clinical diagnosis analysis of risk factors keratoconus. Methods In this retrospective case analysis, 13 patients (20 eyes, group) were diagnosed accepted treatment Shandong Eye Institute January 1997 December 2012. Correspondingly, 18 (25 randomly selected during same period. The mean ages group 18.9±2.8 years (15-28 years) 24.3±9.1 (19-48 years),...

Skin flap transplantation is one of the most common tissue methods for wound repair and organ reconstruction in plastic surgery. During process, inflammatory response transplanted angiogenesis are critical to successful rate skin transplantation. In recent years, improve biocompatibility cell affinity biomedical materials, modified biomaterials have gradually become a popular subject scientific researches. our study, IL-4 expanded polytetrafluoroethylene (e-PTFE) surgical patch IL4-e-PTFE...

Objective To compare the outcomes of using fresh and glycerin-cryopreserved corneal tissue in treating purulent keratitis with deep anterior lamellar keratoplasty.Methods This was a retrospective case series study.Thirty-two patients (32 eyes) successfully underwent keratoplasty (DALK) Shandong Eye Hospital from January 2011 to August 2012.Based on method for preserving tissue,all were divided into (FCT) group (13 cases) (GCCT) (19 cases).Data donor,complications,graft status visual outcome...

Objective: To observe the efficacy and safety of wavefront-guided transepithelial photorefractive keratectomy (WG-TransPRK) with simultaneous accelerated corneal collagen cross-linking (A-CXL) in early-stage keratoconus. Methods: In this retrospective study, twelve eyes 7 patients early keratoconus underwent WG-TransPRK A-CXL. Visual acuity, refractive status, topography, confocal microscopy aberrations were examined before treatment 1 week, month, 3 months, 6 12 months after surgery....

Abstract The aim of this study was to develop a predictive model for subclinical keratoconus (SKC) based on decision tree (DT) algorithms. A total 194 eyes (including 105 normal and 89 SKC) were included in the double-center retrospective study. Data separately used training validation databases. baseline variables derived from tomography biomechanical imaging. DT models generated database using Chi-square automatic interaction detection (CHAID) classification regression (CART)...