- Anesthesia and Pain Management
- Anesthesia and Sedative Agents
- Heart Rate Variability and Autonomic Control
- Non-Invasive Vital Sign Monitoring
- Nausea and vomiting management
- Anesthesia and Neurotoxicity Research
- Natural Compounds in Disease Treatment
- EEG and Brain-Computer Interfaces
- Endoplasmic Reticulum Stress and Disease
- Hemodynamic Monitoring and Therapy
- Pancreatic function and diabetes
- Phytochemistry and Bioactivity Studies
- Cardiovascular and exercise physiology
- Ethnobotanical and Medicinal Plants Studies
- Streptococcal Infections and Treatments
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Pancreatitis Pathology and Treatment
- Cardiac Ischemia and Reperfusion
- Infective Endocarditis Diagnosis and Management
- Ocular Diseases and Behçet’s Syndrome
- Neurological and metabolic disorders
- Renal Diseases and Glomerulopathies
- Chronic Kidney Disease and Diabetes
- Cardiac, Anesthesia and Surgical Outcomes
- Liver Disease Diagnosis and Treatment
National Taiwan University Hospital
2002-2024
Kangmei Pharmaceutical (China)
2022-2023
Chinese People's Liberation Army
2021
People's Liberation Army No. 150 Hospital
2021
Dalian Medical University
2020
First Affiliated Hospital of Dalian Medical University
2020
Southern Medical University
2010-2018
Nanfang Hospital
2010-2018
Ruijin Hospital
2018
Tongji Hospital
2018
The effect of air pollution on the changing pattern glomerulopathy has not been studied. We estimated profile and temporal change in glomerular diseases an 11-year renal biopsy series including 71,151 native biopsies at 938 hospitals spanning 282 cities China from 2004 to 2014, examined association long-term exposure fine particulate matter <2.5 μm (PM2.5) with glomerulopathy. After age region standardization, we identified IgA nephropathy as leading type glomerulopathy, a frequency 28.1%,...
The (pro)renin receptor (PRR) is a transmembrane protein with multiple functions. However, its regulation and role in the pathogenesis of CKD remain poorly defined. Here, we report that PRR downstream target an essential component Wnt/ β -catenin signaling. In mouse models, induction by ischemia-reperfusion injury (IRI), adriamycin, or angiotensin II infusion upregulated expression kidney tubular epithelium. Immunohistochemical staining biopsy specimens also revealed renal human CKD....
// Chaolin Huang 1 , Yuanhong Chen Hang Liu Jing Yang Xuejing Song Junping Zhao Na He Chengji J. Zhou 2 Yongping Wang Changjiang and Qiaoxiang Dong Institute of Environmental Safety Human Health, School Laboratory Medicine Life Science, Wenzhou Medical University, 325035, P.R. China Department Biochemistry Molecular Medicine, University California at Davis, Sacramento, CA 95817, USA Correspondence to: Dong, email: dqxdong@163.com Huang, cjhuang5711@163.com Keywords: CSCs; celecoxib; PGE ;...
Objective: To investigate the predictive value and clinical significance of alpha-fetoprotein (AFP) levels in prognosis patients with liver failure treated artificial plasma exchange (PE). Methods: A retrospective analysis was conducted on data 96 patients. All underwent therapy addition to internal medicine treatments. Based AFP test results, were divided into a low-AFP group (AFP < 100 ng/mL, n = 32), medium-AFP (100 ≤ 200 high-AFP ≥ 32). Serum measured before (2nd day admission), 1st,...
The present study was designed to develop a combined spinal/epidural anesthetic technique for cesarean section. We compared the effects of different doses intrathecal hyperbaric bupivacaine (0.5%) with epidural lidocaine (2%). attempted interrupt somatosensory pathways spinal anesthesia but avoid acute high thoracic sympathetic block. visceral afferent were be blocked relatively slowly lidocaine. Eighty term parturients randomly divided into four groups. In Group A, 2.5 mg intrathecally 22.2...
Paced breathing is a frequently performed technique for cardiovascular autonomic studies. The relative timing of inspiration and expiration during paced breathing, however, not consistent. We, therefore, examined whether indexes heart rate variability spontaneous baroreflex sensitivity would be affected by the respiratory time ratio that set. We studied 14 healthy young adults who controlled their rates to either 0.1 or 0.25 Hz in supine sitting positions. Four different...
Renal biopsies performed in diabetic patients are increasing and becoming more complex. Comprehensive data on modern spectrum of biopsy-proven renal disease Chinese lacking.In a nationwide biopsy survey including 71,151 native from 2004 to 2014, were identified according the clinical diagnosis referral records. The extracted records pathological reports.A total 1,604 patients, 61 with T1DM, analyzed this study. median age is 51.39 ± 11.37 years. Male accounted for 58% population. We found...
Abstract Purpose Low values of heart rate deceleration capacity (DC) and asymmetry (HRA) are associated with cardiovascular risks. Slow respiration has been proven to enhance the magnitudes these indexes, but individual inspiratory (T I ) expiratory E durations were not controlled in most studies. This study aims examine whether effects T on indexes would be same and, if not, how adjust maximize effect slow respiration. Methods We evaluated 14 seated healthy young adults who randomly their...
Background Nonsteroidal anti-inflammatory drugs (NSAIDs) are widely used to enhance opioid analgesia in the acute pain service. The question, however, of whether NSAIDs produce a similar extent potentiation among different types pain, has not been thoroughly investigated. Materials and Methods A randomized, placebo-controlled, double-blind study was performed characterize analgesic effect tenoxicam, long-acting NSAID, on resting wound evoked uterine cramping after cesarean section. Saline (n...
Anti-glomerular basement membrane (anti-GBM) disease is characterized by crescentic glomerulonephritis with immunoglobulin G (IgG) autoantibodies to the non-collagenous (NC1) domain of α3(IV) collagen presenting along GBM. The patient clinically manifests rapidly progressive (RPGN) pulmonary hemorrhage (Goodpasture syndrome). In rare cases, other immunocomplexes IgA or IgM are involved, but their specificities have not been determined. We report a case 31-year-old female who was diagnosed as...
Treatment with the antileukemic agent asparaginase can induce acute pancreatitis, but pathophysiology remains obscure. In liver of mice, eukaryotic initiation factor 2 (eIF2) kinase general control nonderepressible (GCN2) is essential for mitigating metabolic stress caused by asparaginase. We determined consequences treatment on pancreata wild-type (WT, GCN2-intact) and GCN2-deleted (ΔGcn2) mice. Mean pancreas weights in ΔGcn2 mice treated 8 days were increased (P < 0.05) above all other...
Pain is a common side effect during propofol injection [1]. intensity can be reduced by injecting the drug into larger vein in antecubital fossa [1,2] or diluting it with Intralipid 5% dextrose [3,4]. Nevertheless, fast-flowing intravenous infusion did not have expected [5,6]. Moreover, reported that increasing diluent flow increases pain associated injection. There less when carrier (IV) fluid stopped completely and only undiluted infused [7]. Since this finding has been proved, we designed...
Accelerations and decelerations of heart rate are nonsymmetrical in the magnitude number beat-to-beat changes. The asymmetric features variability related to respiratory durations. To explore link between respiration asymmetry (HRA), we evaluated 14 seated, healthy young adults who breathed with nine combinations inspiration duration (
The release of a tourniquet produces reactive oxygen species (ROS), which can cause ischemia-reperfusion injury. We investigated the effects on ROS production in 22 adult ASA physical status I–II patients sedated with small-dose propofol infusion and IV midazolam undergoing elective total knee replacement under intrathecal anesthesia, allocated randomly to one two groups. In Propofol group, sedation was performed 0.2 mg/kg followed by at rate 2 mg · kg−1 h−1. Control 5 given. measured...