To compare the pulmonary chest CT findings of patients with COVID-19 pneumonia those other types viral pneumonia.This retrospective review includes 154 RT-PCR-confirmed diagnosed between February 11 and 20, 2020, 100 April 2011 December 2020 from two hospitals. High-resolution (HRCT) was performed. Data on location, distribution, attenuation, maximum lesion range, lobe involvement, number lesions, air bronchogram signs, Hilar mediastinal lymph node enlargement, pleural effusion were...

The metabolic profiles of Sprague–Dawley rat pancreases were investigated by high‐resolution magic angle spinning proton magnetic resonance spectroscopy ( 1 H NMR) combined with principal components analysis (PCA) to discriminate pancreatic cancer from chronic pancreatitis. Intact tissue samples obtained rats histologically proven n = 5), pancreatitis and two matched controls 5 per group). Two NMR experiments, single‐pulse Carr–Purcell–Meiboom–Gill, carried out separately. Increases in...

Abstract Purpose Emerging evidence shows that immune checkpoint inhibitors lead to durable responses in a variety of cancers, including nasopharyngeal carcinoma (NPC), however, combination approaches (i.e., stereotactic body radiation therapy, SBRT) are required extend this benefit beyond subset patients. This study retrospectively evaluated eight recurrent/metastatic NPC patients, investigate how could potentiate PD-1 inhibition therapy. Methods Between September 2016 and July 2017,...

Objective To investigate microcirculatory differences between pathologic types of kidney tumor using 320-slice dynamic volume CT perfusion. Methods Perfusion imaging with was prospectively performed in 85 patients pathologically proven clear cell renal carcinoma (RCC) (n = 66), papillary RCC 7), chromophobe 5), angiomyolipoma (AML) minimal fat or 78). Equivalent blood (Equiv BV), permeability surface-area product (PS; clearance/unit permeability), and flow (BF) normal cortex were measured...

Background: Extrapancreatic perineural invasion (EPNI) increases the risk of postoperative recurrence in pancreatic ductal adenocarcinoma (PDAC). This study aimed to develop and validate a computed tomography (CT)-based, fully automated preoperative artificial intelligence (AI) model predict EPNI patients with PDAC. Methods: The authors retrospectively enrolled 1065 from two Shanghai hospitals between June 2014 April 2023. Patients were split into training ( n =497), internal validation...

The etiology and pathogenesis of pancreatitis remains unclear. In the presence pancreatic inflammation, metabolite abnormalities appear before transformation tissue structure changes in functions occur. Detection levels facilitates a greater understanding pathophysiological events aids early diagnosis disease. this study, metabolic profiles from pancreas Wistar rats were examined using high-resolution proton magic angle spinning nuclear magnetic resonance (MAS NMR) spectroscopy to...

Chronic pancreatitis is an inflammatory disease of the pancreas characterized by progressive tissue destruction and fibrogenesis. The development chronic associated with immune cell dysregulation. Currently, specific effective treatment remains absent.By using L-arginine induced mouse model, we tested therapeutic potential hydrogen, a strong hydroxyl radicals scavenger, in model. Tissue inflammation, damage fibrosis were analyzed on HE, TUNEL, MPO, sirius staining. Pancreas levels MDA...

To investigate the monoexponential and biexponential apparent diffusion parameters in different anatomical regions of healthy pancreas using intravoxel incoherent motion (IVIM) weighted imaging (DWI).Fifty-seven volunteers (age, 45.0 ± 10.8 years) were recruited. DWI was performed with 9 b-values (0, 20, 50, 100, 200, 400, 600, 800, 1000 s/mm(2) , respectively). The ADC calculated for all linear regression yielding ADCtotal . ADCb value DWI, slow component (ADCslow ), microcirculation...

Acute pancreatitis (AP) is an acute inflammatory condition of the pancreas. The symptoms, treatment, and prognosis mild severe AP are different, a potentially life-threatening disease with high incidence complications mortality rate. Thus, it urgent to develop effective approach reliably discriminate between AP.We have developed novel gadolinium-diethylenetriaminepentaacetic (Gd-DTPA)-loaded mannosylated liposomes (named thereafter M-Gd-NL) that preferably target macrophages in AP. targeting...

Abstract Purpose: To determine the reproducibility of 3D proton magnetic resonance spectroscopic imaging ( 1 H‐MRSI) human prostate in a multicenter setting at 1.5T. Materials and Methods: Fourteen subjects were measured twice with point‐resolved spectroscopy (PRESS) H‐MRSI using an endorectal coil. MRSI voxels selected peripheral zone combined central gland same location both measurements. Voxels approved spectral quality included to calculate Bland–Altman parameters for from choline plus...

To assess the usefulness of factors unique to NCCT for prediction ESWL outcomes in patients with pancreatic duct stones.We retrospectively evaluated 148 multiple PDS who had undergone therapy. All received an examination both before and after ESWL. The following parameters were measured recorded: patient characteristics including sex age; mean stone length, volumes ESWL, value CT attenuation, standard deviation variation coefficient skin-to-stone distance, diameter; outcome indexes clearance...

To investigate the effects of region interest (ROI) sizes on apparent diffusion coefficient (ADC) measurements for differentiation normal pancreas (NP), pancreatic ductal adenocarcinoma (PDAC) and mass-forming chronic pancreatitis (MFCP).There were no significant differences mean ADCs measured by 12 different-size ROIs MFCP, or PDAC NP (P = 0.858-1.0). With increase ROI size (≥ 55 mm2), significantly lower than those (all P < 0.05), but there was difference accuracy in ADC differentiating...

To study the difference of microvessel density (MVD) between malignant and benign hepatic lesions relationship MVD dynamic enhanced magnetic resonance imaging (MRI) for evaluation microvessels within lesions.A total 265 specimens hepatocellular carcinoma (HCC), 122 cirrhosis tissues 22 were enrolled by immunohistochemistry on tissue microarray, which 49 underwent MRI examination before surgery, then contrast-to-noise ratios (CNR) enhancement index (EI) in all phases calculated. Pearson...

Background: In patients with chronic left ventricular dysfunction, the size of viable cardiac muscle is correlated prognosis and outcome myocardial revascularization. Purpose: To evaluate diagnostic value various imaging techniques in determination ischemia viability. Material Methods: A animal model was established, which 10 pigs underwent magnetic resonance (MRI), positron emission tomography (PET), single-photon computed ( 201 Tl SPECT) before 1–2 months after modeling. The necrosis...

In recent years, increasing attention has been paid to cryptogenic stroke (CS) caused by the patent foramen ovale (PFO).This study aims evaluate value of microbubble transcranial Doppler (MB-TCD) combined with contrast transthoracic echocardiography (cTTE) in diagnosis patients PFO.From January 2014 2019, who suffered from CS were recruited and divided into cTTE group MB-TCD group. All further checked transesophageal (TEE).A total 130 accepted examination, 109 cTTE. group, 52 54 positive...

Ground-based multichannel microwave radiometers (GMRs) can observe the atmospheric radiation brightness temperature at K-bands and V-bands provide humidity profiles with a relatively high temporal resolution. Currently, are operated in many countries to profiles. However, theoretical analysis showed that radiometer be used solar radiation. In this work, we improved control algorithm software of antenna servo system GMR so it could track sun use upgraded During observation, accurately tracked...

Background Even in patients with a successful return of spontaneous circulation (ROSC), outcomes after cardiac arrest (CA) remain poor, some eventually succumbing several months treatment. There is need for early assessment ROSC CA. Therefore, we developed three models predicting death within 6 CA using post-arrest factors, performed external validation, and compared their efficiency. Methods In this retrospective cohort study, 199 aged 18–80 years who experienced either in-hospital or...

A method was established for the determination of main nonnitrogenous organic acids (including acetic, lactic, succinic, maleic, tartaric, oxalic, fumaric, citric, and aconitic acids) three inorganic anions (Cl-, SO4(2-) PO4(3-)) in sugarcane molasses alcohol waste by ion chromatography with solid-phase extraction. The diluted sample solution purified strong anion exchange (SAX) extraction (SPE) a small packed column to remove most sugar, pigment other interfering matrices. eluate obtained...

Objective To discuss the value of combining secretin-enhanced MR cholangiopancreatography (MRCP) and conventional MRI in evaluation chronic pancreatitis (CP).Methods Seventeen normal volunteers,and 36 patients with CP were enrolled this study.Thick slab two dimension MRCP sequence,coronal T2 weighted sequence performed on all subjects.The changes pancreatic ducts observed before after injection secretin.The exocrine function pancreas was evaluated using duodenal filling (DF)...