A5024003056- Prostate Cancer Diagnosis and Treatment
- MRI in cancer diagnosis
- Prostate Cancer Treatment and Research
- Radiomics and Machine Learning in Medical Imaging
- Urologic and reproductive health conditions
- Advanced MRI Techniques and Applications
- Bladder and Urothelial Cancer Treatments
- Medical Imaging Techniques and Applications
- Urinary and Genital Oncology Studies
- Urological Disorders and Treatments
- Cardiac Imaging and Diagnostics
- Colorectal Cancer Screening and Detection
- Radiopharmaceutical Chemistry and Applications
- Lanthanide and Transition Metal Complexes
- Aortic Disease and Treatment Approaches
- Breast Lesions and Carcinomas
- Medical Image Segmentation Techniques
- Aortic aneurysm repair treatments
- Pelvic floor disorders treatments
- Immunotherapy and Immune Responses
- Medical Imaging and Analysis
- Endometrial and Cervical Cancer Treatments
- Advanced Radiotherapy Techniques
- Cancer Immunotherapy and Biomarkers
- Advanced X-ray and CT Imaging
Radboud University Nijmegen
2016-2025
Radboud University Medical Center
2016-2025
Andros Mannenkliniek
2021-2025
Radboud Institute for Molecular Life Sciences
2024
Norwegian Womens Public Health Association
2023
Itasca Consultants (France)
2023
Policlinico Umberto I
2022
National Institutes of Health
2022
National Cancer Institute
2022
Cleveland Clinic
2022
The aim was to develop clinical guidelines for multi-parametric MRI of the prostate by a group experts from European Society Urogenital Radiology (ESUR), based on literature evidence and consensus expert opinion. True evidence-based could not be formulated, but compromise, reflected "minimal" "optimal" requirements has been made. scope these ESUR is promulgate high quality in acquisition evaluation with correct indications cancer across whole Europe eventually outside Europe. optimal...
Accurate detection of lymph-node metastases in prostate cancer is an essential component the approach to treatment. We investigated whether highly lymphotropic superparamagnetic nanoparticles, which gain access lymph nodes by means interstitial–lymphatic fluid transport, could be used conjunction with high-resolution magnetic resonance imaging (MRI) reveal small nodal metastases.
There is growing interest to implement multiparametric magnetic resonance imaging (mpMRI) and MR-guided biopsy (MRGB) for biopsy-naïve men with suspected prostate cancer.Primary objective was compare evaluate an MRI pathway a transrectal ultrasound-guided (TRUSGB) in prostate-specific antigen levels of ≥3ng/ml.A prospective, multicenter, powered, comparative effectiveness study included 626 patients (from February 2015 2018).All underwent prebiopsy mpMRI followed by systematic TRUSGB. Men...
To retrospectively determine the relationship between apparent diffusion coefficients (ADCs) obtained with 3.0-T diffusion-weighted (DW) magnetic resonance (MR) imaging and Gleason grades in peripheral zone prostate cancer.The requirement to obtain institutional review board approval was waived. Fifty-one patients cancer underwent MR before prostatectomy, including DW b values of 0, 50, 500, 800 sec/mm(2). In prostatectomy specimens, separate slice-by-slice determinations grade groups were...
PURPOSE: To evaluate the comparative accuracy of magnetic resonance (MR) imaging relative to mammography and ultrasonography (US) for assessing extent breast tumors. MATERIALS AND METHODS: Histologic results preoperative findings (mammography, US, MR imaging) were analyzed regarding tumor size multifocality 61 tumors in 60 women undergoing mastectomy carcinoma. RESULTS: In 10% cases, index was not seen at mammography. With 15% recognized, while missed 2% On mammographic US images,...
Purpose: To prospectively determine the accuracies of T2-weighted magnetic resonance (MR) imaging, dynamic contrast material–enhanced MR and quantitative three-dimensional (3D) proton spectroscopic imaging entire prostate for cancer localization, with whole-mount histopathologic section findings as reference standard. Materials Methods: This study was approved by institutional review board, informed consent obtained from all patients. Thirty-four consecutive men a mean age 60 years...
Prostate cancer is one of the major causes death for men in western world. Magnetic resonance imaging (MRI) being increasingly used as a modality to detect prostate cancer. Therefore, computer-aided detection MRI images has become an active area research. In this paper we investigate fully automated system which consists two stages. first stage, initial candidates using multi-atlas-based segmentation, voxel feature extraction, classification and local maxima detection. The second stage...
To evaluate which parameters of dynamic magnetic resonance (MR) imaging and T2 relaxation rate would result in optimal discrimination prostatic carcinoma from normal peripheral zone (PZ) central gland (CG) tissues to correlate these with tumor stage, Gleason score, patient age, markers.Of 58 patients carcinoma, 36 were included for analysis. Patients underwent MR at 1.5 T an endorectal-pelvic phased-array coil subsequently prostatectomy. A T2-weighted turbo spin-echo sequence,...
PURPOSE: To assess the utility of gadolinium-enhanced dynamic magnetic resonance (MR) imaging with turbo fast low-angle shot (TurboFLASH) technique in differentiation benign from malignant lesions breast. MATERIALS AND METHODS: Contrast material-enhanced MR images were obtained at intervals 2.3 seconds for 2 minutes. After first four obtained, contrast medium was intravenously injected within 10 seconds. Lesions that enhanced 11.5 after aorta opacified regarded as malignant. more than...
Undetected cancer in repeat transrectal ultrasound guided prostate biopsies patients with increased specific antigen greater than 4 ng/ml is a considerable concern. We investigated the tumor detection rate of suspicious regions on multimodal 3 Tesla magnetic resonance imaging and subsequent biopsy 68 men negative biopsies. compared results to those matched population. Also, we determined clinical significance detected tumors.A total 71 consecutive 2 or sessions underwent imaging. In this was...
Background Prostate MRI is used widely in clinical care for guiding tissue sampling, active surveillance, and staging. The Imaging Reporting Data System (PI-RADS) helps provide a standardized probabilistic approach identifying clinically significant prostate cancer. Despite widespread use, the variability performance of across practices remains unknown. Purpose To estimate positive predictive value (PPV) PI-RADS detection high-grade cancer imaging centers. Materials Methods This...