A5020303566- Autism Spectrum Disorder Research
- Genetics and Neurodevelopmental Disorders
- Memory and Neural Mechanisms
- Memory Processes and Influences
- Attention Deficit Hyperactivity Disorder
- Functional Brain Connectivity Studies
- Muscle Physiology and Disorders
- Cardiomyopathy and Myosin Studies
- Identity, Memory, and Therapy
- Child Development and Digital Technology
- Cognitive Abilities and Testing
- Grit, Self-Efficacy, and Motivation
- Neural and Behavioral Psychology Studies
- Congenital heart defects research
- Neurogenetic and Muscular Disorders Research
- Stress Responses and Cortisol
- Olfactory and Sensory Function Studies
- EEG and Brain-Computer Interfaces
- Genetic Neurodegenerative Diseases
- Perfectionism, Procrastination, Anxiety Studies
- Visual perception and processing mechanisms
- Neuroscience and Neuropharmacology Research
- Neurogenesis and neuroplasticity mechanisms
- Peripheral Nerve Disorders
- Congenital limb and hand anomalies
University of California, Davis
2016-2025
University of British Columbia
2024
Western University of Health Sciences
2024
Institute of Behavioral Sciences
2022
McMaster University
2021
Toronto Metropolitan University
2021
University of the West of England
2021
University of California Davis Medical Center
2020
Massachusetts Institute of Technology
2019
Nevro (United States)
2019
The hippocampus is critically involved in episodic memory, yet relatively little known about how the development of this structure contributes to memory during middle late childhood. Previous research has inconsistently reported associations between hippocampal volume and performance period. We argue that inconsistency may be due assessing as a whole, propose examine separately for subregions along longitudinal axis hippocampus. In present study, we examined age-related differences volumes...
Of the 1 in 36 individuals United States who are diagnosed with autism spectrum disorder, nearly 40% also have intellectual disability (ID). The cortex has been widely implicated neural processes underlying autistic behaviors as well ability. Thus, neuroimaging features such cortical thickness of particular interest a possible biomarkers condition. However, studies often fail to include ID. As result, there few across entire range abilities. This study used MRI evaluate young children (n =...
This research investigated whether episodic memory development can be explained by improvements in relational binding processes, involved forming novel associations between events and the context which they occurred. Memory for item–space, item–time, item–item relations was assessed an ethnically diverse sample of 151 children aged 7–11 years 28 young adults. Item–space reached adult performance 9½ years, whereas item–time improved into adulthood. In path analysis, but not best memory....
Abstract Introduction Heterogeneity of segmentation protocols for medial temporal lobe regions and hippocampal subfields on in vivo magnetic resonance imaging hinders the ability to integrate findings across studies. We aim develop a harmonized protocol based expert consensus histological evidence. Methods Our international working group, funded by EU Joint Programme–Neurodegenerative Disease Research (JPND), is toward production reliable, validated, regions. The group uses novel postmortem...
The core symptoms of autism spectrum disorder (ASD) are widely theorized to result from altered brain connectivity. Diffusion-weighted magnetic resonance imaging (DWI) has been a versatile method for investigating underlying microstructural properties white matter (WM) in ASD. Despite phenotypic and etiological heterogeneity, DWI studies majority male samples older children, adolescents, adults with ASD have largely reported findings decreased fractional anisotropy (FA) across several...
Relational memory improves during middle childhood and adolescence, yet the neural correlates underlying those improvements are debated. Although for spatial, temporal, other associative relations requires hippocampus, it is not established whether within-individual changes in hippocampal structure contribute to from into adolescence. Here, we investigated how structural head, body, tail subregions predict capacity remember item-space, item-time, item-item relations. Memory each relation...
Abstract Previous studies have reported alterations in cortical thickness autism. However, few included enough autistic females to determine if there are sex specific differences structure This longitudinal study aimed investigate and trajectory of thinning across childhood. Participants 290 (88 females) 139 nonautistic (60 individuals assessed at up 4 timepoints spanning ~2–13 years age (918 total MRI timepoints). Estimates early late childhood as well the were modeled using spatiotemporal...
The aims of this study were to identify a subset children with autism spectrum disorder (ASD) and co-occurring symptoms psychopathology, evaluate associations between subgroup biological sex amygdala volume.Participants included 420 (ASD: 91 girls, 209 boys; typically developing controls: 57 63 boys). Latent profile analysis was used ASD subgroups based on adaptive functioning, cognitive development, severity. Differences in the proportions girls boys across evaluated. Magnetic resonance...
Episodic memory develops during childhood and adolescence. This trajectory depends on several underlying processes. In this article, we first discuss the development of basic binding processes (e.g., by which elements are bound together to form a episode) control reasoning metamemory processes) involved in episodic remembering. Then, role these false-memory formation. subsequent sections, examine neural substrates memory. Finally, atypical As proceed through suggest potential avenues for...
One of the most important factors driving development memory during childhood is mnemonic control, or capacity to initiate and maintain processes that guide encoding retrieval operations. The ability selectively attend encode relevant stimuli a particularly useful form one undergoes marked improvement over childhood. We hypothesized structural integrity white matter tracts, in particular those connecting medial temporal lobe regions other cortical areas, and/or frontal parietal control...
Altered amygdala development is implicated in the neurobiology of autism, but little known about coordinated brain regions directly connected with amygdala. Here we investigated volumetric an amygdala-connected network, defined as set monosynaptic connections amygdala, autism from early to middle childhood. A total 950 longitudinal structural MRI scans were acquired 282 children (93 female) and 128 typical (61 at up four time points (mean ages: 39, 52, 64, 137 months, respectively). Volumes...
The goal of the present study was to investigate whether hippocampal contribution episodic memory retrieval varies as a function age (8-9 versus 10-11 adults), performance levels (high low) and sub-region (head, body, tail). We examined fMRI data collected during from large sample (N=126). Participants judged stimulus had been encoded previously, and, if so, which three scenes it paired with (i.e., source judgment). For 8- 9-years-olds well low-performing 10- 11-year-olds, activations did...