A5026167005- Electroconvulsive Therapy Studies
- Treatment of Major Depression
- Sphingolipid Metabolism and Signaling
- Ginger and Zingiberaceae research
- Epilepsy research and treatment
- Bipolar Disorder and Treatment
- Functional Brain Connectivity Studies
- Boron Compounds in Chemistry
- Boron and Carbon Nanomaterials Research
- Carbohydrate Chemistry and Synthesis
- EEG and Brain-Computer Interfaces
- Peroxisome Proliferator-Activated Receptors
- Radiopharmaceutical Chemistry and Applications
- Drug-Induced Hepatotoxicity and Protection
- RNA Interference and Gene Delivery
- Child and Adolescent Psychosocial and Emotional Development
- Neural dynamics and brain function
- Mental Health Research Topics
- Garlic and Onion Studies
- Axial and Atropisomeric Chirality Synthesis
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Transcranial Magnetic Stimulation Studies
- Takotsubo Cardiomyopathy and Associated Phenomena
- Synthesis of Organic Compounds
- Liver physiology and pathology
Nagoya City University
2006-2024
Osaka City University
2010-2023
Osaka Metropolitan University
2023
Doshisha University
2018
Kyoto Prefectural University
2018
Tokushima University
1993-2007
Mizuho (Japan)
2006-2007
Tokatsu Hospital
2005
Showa University
2001
British Society of Periodontology
2001
ADVERTISEMENT RETURN TO ISSUEPREVNoteNEXTStereospecific Total Syntheses of Sphingosine and Its Analogues from l-SerineHideki Azuma, Seizo Tamagaki, Kenji OginoView Author Information Department Bioapplied Chemistry, Faculty Engineering, Osaka City University, Sugimoto 3-3-138, Sumiyoshi-ku, 558-8585, Japan Cite this: J. Org. Chem. 2000, 65, 11, 3538–3541Publication Date (Web):May 4, 2000Publication History Received14 September 1999Published online4 May 2000Published inissue 1 June...
Ictal electroencephalography (EEG) parameters in electroconvulsive therapy (ECT) for depression reportedly correlate with therapeutic response and stimulus dosage, particularly right unilateral (RUL) ECT. The authors examined ictal EEG as predictors of effectiveness bilateral (BL) sine pulse wave A total 30 consecutive depressed inpatients who had not responded to standard pharmacotherapy were treated using BL ECT given either or mode. (e.g. regularity, postictal suppression) manually rated...
Abstract This study investigated longitudinal changes and predictive factors for psychological distress among 85 newly diagnosed advanced non‐small cell lung cancer (NSCLC) patients. Whereas tension‐anxiety after diagnosis ( T 1) was significantly reduced at two months 2) six 3) depression‐dejection 1 2, other forms of distress, including anger–hostility, vigor, fatigue, confusion, did not show significant changes. Total mood disturbance change. Only a higher total predictor 3. These...
The development of boron agents with integrated functionality, including biocompatibility, high content, and cancer cell targeting, is desired to exploit the therapeutic efficacy neutron capture therapy (BNCT). Here, we report BNCT using a HER-2-targeted antibody-conjugated nitride nanotube/β-1,3-glucan complex. anticancer effect our system was 30-fold that clinically available agent l-BPA/fructose
Background: Substance P (SP) is a multifunctional neuropeptide that transmits pain signals, regulates the immune system, and may modulate emotional stress. SP stimulates bone resorption activity of osteoclasts, level in gingival crevicular fluid correlated with degree periodontal inflammation. However, exact roles metabolism diseases are poorly understood. To elucidate effect stress on metabolism, we investigated osteoblastic cell differentiation presence lipopolysaccharide from...
Several studies have noted modest interrater reliability of clinical electroencephalogram (EEG) interpretations. Moreover, no study to date has investigated a means improve the observed agreement. The purpose present was examine (i). EEG interpretations among three raters (two psychiatrists and one pediatrician); (ii). how by establishing consensus guideline for interpretation. Three raters, two pediatrician, interpreted 100 consecutive recorded at Tajimi General Hospital. After discussing...
Worldwide use of the Hamilton Rating Scale for Depression (HRSD) presupposes that depression symptomatology can be measured same way across countries but no empirical study has yet examined this issue. We therefore cross-cultural consistency factor structure HRSD.A 17-item HRSD data were sought 5,185 individuals diagnosed with major in Japan, Europe and North America. Candidate structures obtained simultaneous component analysis (SCA) three cultures. They then submitted to multiple-group...
Objective: Studies of the cognitive effects electroconvulsive therapy (ECT) have resulted in controversial findings up to now, partly because researchers and reviewers not always made a clear distinction among various aspects cognition there are many parameters involved administration ECT that potential impact on cognition. The present study focused sine pulse waveforms anterograde memory nonmemory functions. Methods: We assigned 18 patients with unipolar major depression or bipolar I II...
It is important to prevent and improve diabetes mellitus its complications in a safe low-cost manner. S-Allyl cysteine, an aged garlic extract with antioxidant activity, was investigated determine whether S-allyl cysteine can type 2 Otsuka Long-Evans Tokushima Fatty rats nonalcoholic fatty liver disease. Male age-matched were used divided into two groups at 29 weeks of age. (0.45% diet) administered for 13 weeks. Rats killed 43 age, detailed analyses performed. improved hemoglobinA1c, blood...
Naturally occurring symbioramide, (2S,3R,2'R,3'E)-N-(2'-hydroxy-3'-octadecenoyl)-dihydrosphingosine 1a, was synthesized from d-erythro-dihydrosphingosine (amino part, 2) and (2R,3E)-2-hydroxy-3-octadecenoic acid (acid 3a), both of which were prepared l-serine. Its diastereomer, (2S,3R,2'S,3'E)-1b, having an enantiomer the unnatural-type part that d-mannitol, its corresponding (Z)-isomers, (2S,3R,2'R,3'Z)-1c (2S,3R,2'S,3'Z)-1d, also prepared. The antileukemic activities 1a-d against HL-60...
S-allyl cysteine (SAC) is the most abundant compound in aged garlic extracts (AGEs). AGE has been reported to ameliorate oxidative damage implicated a variety of diseases. However, effects SAC have not established liver cirrhosis. The aim this study was examine effect therapeutic administration cirrhosis by chronic carbon tetrachloride (CCl4) rats. or other compounds were administered from 4 weeks when fibrosis confirmed be process. CCl4 elevated plasma alanine aminotransferase, lipid...
Nifedipine is used as a long-acting vasodilator, and primary side effect the induction of gingival overgrowth, which characterized by an accumulation collagenous components within connective tissue. To elucidate mechanisms nifedipine-induced we investigated nifedipine on Type I collagen metabolism in gingiva rats.Twenty-day-old rats were fed powdered diet containing or lacking for 3 to 55 days. Immunohistochemical analysis with anti-Type antibody was employed examine density Total RNAs...
Background and Objective: The effect of enamel matrix derivative (EMD) on bone differentiation remains unclear. Transforming growth factor β1 (TGF ‐ β1) is reported to be contained in EMD. aim this study was clarify the EMD osteoblastic cell possible role TGF β1. Material Methods: Fetal rat carvarial cells were treated with 10, 50 or 100 µg/ml for 5–17 days. Alkaline phosphatase (ALP) activity nodule formation measured, mRNA expressions proteins core binding analysed. Results: Enamel...
Boron neutron capture therapy (BNCT) is a promising modality for cancer treatment because of its minimal invasiveness. To maximize the therapeutic benefits BNCT, development efficient platforms delivery boron agents indispensable. Here, carborane-integrated immunoliposomes were prepared via an exchanging reaction to achieve HER-2-targeted BNCT. The conjugation anti-HER-2 antibody liposomes successfully endowed these with targeting properties toward HER-2-overexpressing human ovarian cells...