A5075937111- Semiconductor Lasers and Optical Devices
- Spectroscopy and Laser Applications
- Laser Design and Applications
- Photonic and Optical Devices
- Advanced Fiber Laser Technologies
- COVID-19 Clinical Research Studies
- Lung Cancer Diagnosis and Treatment
- Occupational and environmental lung diseases
- Long-Term Effects of COVID-19
- Optical Network Technologies
- Radiomics and Machine Learning in Medical Imaging
- 14-3-3 protein interactions
- COVID-19 and healthcare impacts
- Service-Oriented Architecture and Web Services
- Semiconductor Quantum Structures and Devices
- Pancreatic and Hepatic Oncology Research
- Cancer Treatment and Pharmacology
- Speech and dialogue systems
- Multi-Agent Systems and Negotiation
- RNA modifications and cancer
- Drug Transport and Resistance Mechanisms
- Peptidase Inhibition and Analysis
- Chromatin Remodeling and Cancer
- Advanced Breast Cancer Therapies
- Pharmacological Effects of Medicinal Plants
People's Hospital of Cangzhou
2022-2024
Shandong Provincial Hospital
2013-2024
Shandong First Medical University
2020-2024
Shandong University
2013-2024
Jinan Infectious Disease Hospital
2024
Shaanxi Provincial People's Hospital
2022-2024
Shanxi Medical University
2022-2024
Huazhong University of Science and Technology
2022
ShanghaiTech University
2017-2022
Union Hospital
2022
Coronavirus disease 2019 (COVID‑19) caused by severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2) infection spread worldwide.The aim of the study was to identify clinical characteristics and risk factors associated with incidence SARS ‑CoV‑2 infection.All adult patients (median [IQR] age, 52 [37-58] years) consecutively admitted Dabieshan Medical Center from January 30, 2020 February 11, were collected reviewed. Only diagnosed COVID‑19 according World Health Organization interim...
Abstract Lung cancer is one of the most harmful malignant tumors to human health. The accurate judgment pathological type lung vital for treatment. Traditionally, requires a histopathological examination determine, which invasive and time consuming. In this work, novel residual neural network proposed identify via CT images. Due low amount images in practice, we explored medical-to-medical transfer learning strategy. Specifically, pre-trained on public medical dataset luna16, then fine-tuned...
Background: Coronavirus disease-2019 (COVID-19) epidemic is spreading globally. Sex differences in the severity and mortality of COVID-19 emerged. This study aims to describe impact sex on outcomes COVOD-19 with a special focus effect estrogen. Methods: We performed retrospective cohort which included 413 patients (230 males 183 females) from three designated hospitals China follow up time January 31, 2020, April 17, 2020. Women over 55 were considered as postmenopausal according previous...
Chaos in nonlinear dynamical systems is featured with irregular appearance and high sensitivity to initial conditions. Near-infrared light chaos based on semiconductor lasers has been extensively studied enabled various applications. Here, we report a fully-developed hyperchaos the mid-infrared regime, which produced from interband cascade subject external optical feedback. Lyapunov spectrum analysis demonstrates that exhibits three positive exponents. Particularly, chaotic signal covers...
Abstract Metastasis accounts for the majority of cases cancer recurrence and death in patients with advanced non-small cell lung (NSCLC). Farnesoid X Receptor (FXR) is a bile acid nuclear receptor that was recently found to be upregulated NSCLC tissues. However, whether how FXR regulates metastasis remains unclear. In present study, it promoted migration, invasion, angiogenic ability cells vitro, increased mouse model vivo. Mechanistic investigation demonstrated specifically bound promoters...
Abstract Purpose To explore the effect of azvudine as compared to paxlovid for oral treatment hospitalized patients with SARS-CoV-2 infection. Methods We analyzed data from a cohort infection in Shandong provincial hospital between February 15 and March 15, 2023. The primary outcome was time sustained clinical recovery through Day 28 secondary outcomes included percentage participants who died any cause by 28, average hospitilization expenses, changes liver kidney function adverse events....
β-Branched simple enamides were hydrogenated to give β-stereogenic amines in quantitative yields and with excellent enantioselectivities.
Abstract Background Information regarding characteristics and risk factors of COVID-19 amongst middle-aged (40–59 years) patients without comorbidities is scarce. Methods We therefore conducted this multicentre retrospective study collected data at admission from three designated hospitals in China. Results Among 119 comorbidities, 18 (15.1%) developed into severe illness 5 (3.9%) died hospital. ARDS (26, 21.8%) elevated D-dimer (36, 31.3%) were the most common complications, while other...
This paper numerically investigates the relative intensity noise of quantum dot lasers through a rate equation model taking into account both spontaneous emission and carrier contributions. In particular, results show that originating from ground excited states significantly enhances laser, while reservoir does not. Simulations also point out large energy interval between confined levels is more suitable for low-intensity operation due to reduced contribution in state. Finally, found have...
A narrow-line-width quantum cascade laser (QCL) is highly demanded for high-resolution spectroscopy of narrow molecule absorption lines. This work shows a low-noise QCL stabilized by strong optical feedback without any phase control. Although usually detrimental to the stability diodes, stable against feedback. The line width proved be insensitive phase, as long strength enough. Therefore, fine control length on subwavelength scale not required, which significantly simplifies experimental...
Background CalliSpheres are drug‐eluting beads used for tumor artery embolization, with clinical benefits in a number of cancer types. The aim the study was to examine and complications patients stage II–IV lung treated embolization versus conventional vascular interventional treatment. Methods This prospective cohort conducted from August 2018 May 2019. were grouped according traditional bronchial arterial infusion chemotherapy (infusion group) or chemoembolization loaded adriamycin...
This work theoretically investigates the frequency noise (FN) characteristics of quantum cascade lasers (QCLs) through a three-level rate equation model, which takes into account both carrier and spontaneous emission Langevin approach. It is found that power spectral density FN exhibits broad peak due to induced variation in upper laser level, enhanced by stimulated process. The amplitude strongly dependent on gain stage number linewidth broadening factor. In addition, an analytical formula...
This work theoretically investigates the frequency noise (FN) characteristics of quantum cascade lasers subject to optical injection through a set coupled rate equations with Langevin sources. It is shown that low-frequency FN completely suppressed by injection, and suppression bandwidth increases increasing ratio. The optimal peak ratio at an 10 dB reaches 2.9 dB. In addition, it found positive detunings close locking boundary invokes additional in spectrum, which can be higher than carrier...
Interband semiconductor lasers subject to optical feedback usually produce rich nonlinear dynamics. However, it is hard destabilize quantum cascade using common feedback, because of its ultrashort carrier lifetime and small linewidth broadening factor. In this work, we show that with a tilted angle can lasers, which three types We observe periodic oscillations angles, quasiperiodic moderate low-frequency large respectively. contrast, type dynamics does not occur well-aligned feedback.
This article experimentally demonstrates that the relative intensity noise (RIN) of a mid-infrared quantum cascade laser is insensitive to optical feedback for ratios up 31% (-5.1 dB). The RIN free-running in range -150 dB/Hz -160 dB/Hz, while induced variation less than ± 2.0 dB. In addition, feedback-induced lasing frequency GHz. Rate equation analyses are good agreement with experimental observations.
Background and objectives: In recent years, there has been a significant increase in the prevalence of pulmonary mycosis disease, its mortality increased. There are very few studies on treating mycosiss with bronchoscopic instillation amphotericin B. This study investigated clinical efficacy safety B for mycosiss. Methods: was multi-centre, retrospective 80 patients who were treated The this treatment evaluated. Results: Eighty included {51 males; mean [standard deviation (SD)] age, 46...
Narrow-linewidth mid-infrared laser sources are highly demanding for high-resolution gas spectroscopy applications. Interband cascade lasers (ICLs) power-efficient emitting in the range. This work unveils low phase noise characteristics of distributed feedback ICLs driven by a battery source. We show that measured spectral linewidth is as narrow 284 kHz (at 1 ms observation time), which smaller than those common quantum lasers. On other hand, raising pump current reduces intrinsic down to 12...
Optical feedback exists in most laser configurations and strongly affects performances depending on the strength, length, phase. In this paper, we investigate frequency comb behaviour of a semiconductor quantum cascade emitting around 4.2 THz with external optical feedback. A periodic evolution inter-mode beatnote from single-line to multiple-line structures is experimentally observed minor change length (phase) wavelength scale. The stability also measured compared same without Furthermore,...
In this work, we propose to employ strong optical feedback narrow the spectral linewidth of quantum cascade lasers without using any phase control. Rate equation analysis demonstrates that beyond a certain level always reduces laser for phase. It is also found becomes less sensitive higher strength. Simulations show with ratio −10 dB can suppress by about two orders magnitude. This in contrast near-infrared diodes, which be easily destabilized feedback.
The diagnostic value of the 9P21 gene determined using fluorescence in situ hybridization (FISH) combined with BRCA1-associated protein 1 (BAP1) and methylthioadenosine phosphorylase (MTAP) expression detection by immunohistochemistry, was investigated serous effusion samples malignant mesothelioma. A total 70 disease were collected from June 2017 to 2020. Following biopsy specimen pathological diagnosis, divided into mesothelioma benign Differential BAP1 MTAP genes identified mesenchymal...