- Immunodeficiency and Autoimmune Disorders
- Drug-Induced Adverse Reactions
- Immune Cell Function and Interaction
- Contact Dermatitis and Allergies
- Inflammatory Myopathies and Dermatomyositis
- Chronic Lymphocytic Leukemia Research
- Blood disorders and treatments
- Eosinophilic Disorders and Syndromes
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Sarcoidosis and Beryllium Toxicity Research
- Pharmacovigilance and Adverse Drug Reactions
- Breast Lesions and Carcinomas
- Autoimmune and Inflammatory Disorders
- Moyamoya disease diagnosis and treatment
- Diabetes and associated disorders
- Mycobacterium research and diagnosis
- Systemic Sclerosis and Related Diseases
- Neurological Complications and Syndromes
- Tuberculosis Research and Epidemiology
- Food Allergy and Anaphylaxis Research
- Genetic Neurodegenerative Diseases
- Autoimmune Bullous Skin Diseases
- Gastrointestinal disorders and treatments
- Nursing education and management
- Hospital Admissions and Outcomes
Concord Repatriation General Hospital
2015-2025
The University of Sydney
2016-2025
Concord Hospital
2004-2020
National Heart Foundation of New Zealand
2020
Centenary Institute
2011
Liverpool Hospital
2004-2010
Leeds General Infirmary
2009
Leeds Teaching Hospitals NHS Trust
2009
Beaumont Hospital
2008-2009
Royal Prince Alfred Hospital
2001-2005
SUMMARY: The following case reports are of two patients who have developed hypersensitivity reactions to the red cell growth hormones, darbepoietin and erythropoietin. subsequent skin testing clinical course suggested that cause these was due excipient polysorbate 80. This finding might implications in recent increase incidence pure aplasia.
Flow cytometric techniques are increasingly used in pretransplant crossmatching, although there remains debate regarding the clinical significance and predictive value of donor-specific antibodies detected by flow cytometry. At least some discrepancies between published studies may arise from differences cutoffs lack standardization test.We selected cut-off values for crossmatching (FCXM) based on correlation retrospective results with occurrence antibody-mediated rejection. The impact...
Hemophagocytic lymphohistiocytosis (HLH) is a rare and often fatal condition characterized by inappropriate immune system activation leading to "cytokine storm", ultimately resulting in end-organ damage. Causes include primary defects genes involved immune-mediated cytolytic pathways, or secondary triggers such as infection malignancy. We describe case of HLH precipitated fungal which occurred consequence immunosuppression for management systemic lupus erythematosus (SLE) necrotizing...
Abstract Hypersensitivity pneumonitis (HP) is an immune‐mediated interstitial lung disease (ILD) relating to specific occupational, environmental or medication exposures. Disease behaviour influenced by the nature of exposure and host response, with varying degrees inflammation fibrosis seen within individuals. The differentiation HP from other ILDs important due distinct causes, pathophysiology, prognosis management implications. This Thoracic Society Australia New Zealand (TSANZ) position...
Sweet's syndrome (SS), a rare reactive neutrophilic dermatosis, has been reported to occur in association with variety of systemic disorders, categorized by von den Diesch into idiopathic, paraneoplastic, pregnancy and parainflammatory subgroups. The group well defined, includes wide spectrum infectious triggers disorders immune dysregulation. To date, however, no cases SS have described the context common variable immunodeficiency (CVID). We report case paediatric-onset SS, previously as...
Reversible Posterior Leukoencephalopathy Syndrome (RPLS) is a relatively recently characterised neurological syndrome, first described by Hinchey et al in 1996, with neuroimaging findings of reversible vasogenic subcortical oedema. The clinical presentation can vary, often non-specific but include headache, global encephalopathy, seizures and visual disturbances. In this article we present such case 79 year old woman, followed discussion the typical presentations, associations,...
Early diagnosis of rheumatoid arthritis allows prompt initiation antirheumatic therapy, which is associated with improved outcome. The use IgM factor, the most widely used serologic test in assisting arthritis, limited by low specificity. An enzyme-linked immunosorbent assay detecting antibodies to cyclic citrullinated peptide (CCP) has been developed apparently higher specificity for arthritis.We aimed evaluate an anti-CCP determining prevalence and titer CCP a group patients chronic...
<h3>ABSTRACT</h3> A 58-year-old man was referred for review due to the finding of splinter haemorrhages and digital infarcts. Further questioning revealed a history unintentional weight loss calf pain. There were no other clinical features endocarditis, clear cause on initial investigations. The discovery widespread thromboembolic disease prompted search malignancy an eventual diagnosis oesophageal adenocarcinoma. Splinter resolved with anticoagulation directed treatment underlying...