Abstract Background Most reported sporotrichosis cases came from South American countries, the USA, India and Japan. This mycosis is also endemic in Northeast China. However, situation not clear for international researchers due to lack of large series English. Objectives To report analyse 457 cases. Methods Retrospective study diagnosed by fungal culture at First Hospital Jilin University 1 January 2007 31 December 2009. Results In this series, male: female ratio was 1:1.42. Mean age 41.2...

In this study, we report a facile method for the preparation of molecularly imprinted polymer based graphene electrochemical detection thiamethoxam residue.

Previous reports on the molecular characteristics of clinical isolates Cryptococcus species in China have focused from southeast China. To obtain a more detailed epidemiology, total 92 cryptococcal were collected Sichuan province. A 24 12 other provinces for comparative study. Genotypes and mating types 116 determined. Among isolates, 43 (19 outside Sichuan) analysed by multi-locus sequence typing (MLST). All type α. Most (114/116) VNI remaining two VGI VGII respectively. MLST results...

Abstract Background Sporotrichosis is a deep mycosis caused by Sporothrix schenckii . It not uncommon in adults and children but very rare infants. Methods We collated series of case reports. Clinical data laboratory therapeutic results 15 infants with cutaneous sporotrichosis were analyzed. Results A total cases aged <10 months (mean age: 5.2 months; 10 male, five female) diagnosed at the Department Dermatology Venereology, First Hospital Jilin University, Changchun, Jilin, China,...

Sporothrix globosa is the main causative agent of sporotrichosis, a common mycosis that usually affects skin, in China. Despite increasing efforts molecular identification this fungal pathogen, its modes transmission and epidemiology remain poorly understood. The goals study were to assess genetic diversity S. using amplified fragment length polymorphism (AFLP) analysis correlation AFLP profiles with geographic origins, growth rates, clinical forms, antifungal susceptibilities isolates. 225...

In this work, novel water-compatible core–shell surface molecularly imprinted polymers with double recognition abilities for highly efficient separation of starch polysaccharide were prepared.

Abstract Background Primary observation of using itraconazole pulse regimen (commonly used for onychomycosis) in five sporotrichosis patients produced satisfactory effect, but there are no randomized controlled trials to assess this and compare with routine continuous regimen. Objectives The aim study was the efficacy safety regimen, as a new treatment option cutaneous sporotrichosis, Methods A prospective, randomized, evaluator‐blind, performed. total 50 were divided randomly into two...

Methyleugenol (Mlg), a natural ingredient of many herbs and used as flavoring substance in dietary products, inhibits inflammation oxidative stress. The aim the study is to explore antioxidative potential Mlg against tert-butyl hydroperoxide (t-BHP)-triggered injury involvement mechanisms. Our findings indicated that exposure significantly alleviated t-BHP-stimulated cytotoxicity, suppressed reactive oxygen species (ROS) generation, increased superoxide dismutase (SOD) glutathione (GSH)...

The aim of this study was to investigate radioprotective effect the polysaccharides from soybean meal (SMP) against X-ray radiation-induced damage in mouse spleen lymphocytes. MTT and comet assay were performed evaluate SMP's ability prevent cell death DNA induced by radiation. results show that, radiation (30 KV, 10 mA, 8 min (4 Gy)) can significantly increase fragmentation Pretreatment with SMP for 2 h before could viability, moreover, reduce damage. percentage tail moment groups lower...

By an oxidative coupling polymerization approach, we have synthesized a novel electroactive polymer with good solubility containing alternating phenyl-capped aniline tetramer in the main chain and azo chromophores side chain. Dielectric properties of as-synthesized were investigated detail gratifying results been observed. Firstly, large enhancement dielectric constant was achieved utilizing method doping conjugated oligoaniline segments hydrochloric acid. Secondly, adjustment implemented...

This study aimed to evaluate the clinical characteristics of infantile hemangiomas (IHs) and safety efficacy long-pulse 1,064-nm neodymium-doped yttrium aluminum garnet (Nd:YAG) laser for definitive treatment IHs in 794 Chinese patients.Infants with who had received Nd:YAG our department last 5 years were recruited. Demographic recorded outcomes assessed. Statistical analyses performed identify factors that affected treatment.The all patients was 87.57%. Efficacy did not depend on sex or...

Pterygium is an inflammatory and degenerative ocular surface disease, in which the conjunctiva on cornea grows to form a fibrous tissue shape of triangle. Although pterygium surgery used broadly clinical practice, its high recurrence rate poses great concern for patients doctors. In present study, we examined effects curcumin apoptosis proliferation human fibroblasts (HPFs) vitro culture system. HPFs were incubated with 24 72 h (5, 20, 80 or 200 µmol/l). The proliferation-inhibiting assayed...

Pediatric patients make a substantial contribution to the epidemiologic profile of sporotrichosis in Jilin Province, region China which disease is strongly endemic. However, exact and clinical manifestations childhood are unclear. The medical records 704 pediatric aged <15 years with diagnosed by fungus culture at Department Dermatology First Hospital University 7-year period (January 2010 December 2016) were reviewed retrospectively. from rural areas located northeast China. Among patients,...

Sporotrichosis is endemic in Jilin Province of Northeast China. While paediatric cases make a substantial contribution to the epidemiological profile sporotrichosis, differences epidemiology and clinical manifestations sporotrichosis between adult patients remain unclear. We retrospectively reviewed records 2968 (2113 aged ≥ 15 years 855 < years) over nine-year period (01/01/2010-31/12/2018-). All were diagnosed with based on fungal culture material from skin lesion. In patients, male:female...

A novel and straightforward approach was employed to augment the dielectric constant diminish elastic modulus of polyurethane (PU) through integration modified silica (NSiO2) into matrix. The incorporation NSiO2 resulted in disruption N–H/C═O hydrogen bonds between PU chains, which subsequently led an enhancement polarizability chains increase PU. Concurrently, addition a reduction (Y) PU, attributed hard domains concurrent Y give rise 60% electromechanical sensitivity at 103 Hz....

Giant condyloma acuminatum, or Buschke–Löwenstein tumour, is a unique variant of anogenital warts. It characterized by locally aggressive behaviour but rarely metastasizes. Many treatment strategies such as radical surgery, radiation and chemotherapy have been used to treat it their efficacy often poor the recurrence rates are high. We report case 16-year-old girl who was treated with oral retinoid combined intramuscular interferon- γ. All lesions cleared within three months. During...

The long-pulsed 1064-nm Nd: YAG laser is effective for treating port-wine stain (PWS). This study evaluated the efficacy and safety of in PWS Chinese patients.A retrospective 130 patients treated with from 2009 to 2011.After treatment, 2, 15, 64, 19 percent experienced < 25%, 25-49%, 50-75%, > 75% lesion clearance, respectively. Purple lesions showed more significant improvement than pink lesions. initial response was blistering, dark gray coloration, or light best occurred 100% (27/27),...

Summary Background An alternative therapy for sporotrichosis is necessary to reduce the treatment time and raise clinical efficacy. The 5‐Aminolevulinic acid‐mediated photodynamic (ALA‐PDT) a promising platform with which treat mycoses. However, despite worldwide prevalence of Sporothrix globosa , causative agent sporotrichosis, effect ALA‐PDT on this pathogen has not been validated. Objectives aim study was evaluate S protection melanin through an in vitro study. mechanisms involved were...

This study aimed to develop an exosome-coated polydatin (PD) nanoparticles (exo-PD) for improving the water solubility and bioavailability of explore its salutary effects on intestinal radiation injury. Exosomes (exo) were extracted from medium human amniotic fluid stem cells (hAFSc). Mice divided into control group, irradiation (IR) irradiation+PD (IR+PD) irradiation+exo (IR+exo) group irradiation+exo-PD (IR+exo-PD) group. The results characterization protein markers, particle size,...