A5100611784- Parathyroid Disorders and Treatments
- Genetic Syndromes and Imprinting
- Cancer-related molecular mechanisms research
- Pancreatic and Hepatic Oncology Research
- Vitamin D Research Studies
- Lipid metabolism and disorders
- Regulation of Appetite and Obesity
- Glioma Diagnosis and Treatment
- Biomarkers in Disease Mechanisms
- Cancer, Hypoxia, and Metabolism
- MicroRNA in disease regulation
- Growth Hormone and Insulin-like Growth Factors
- Gout, Hyperuricemia, Uric Acid
- Metabolomics and Mass Spectrometry Studies
- RNA modifications and cancer
- Immune cells in cancer
- Nanoparticle-Based Drug Delivery
- Diet and metabolism studies
- Circular RNAs in diseases
- Muscle Physiology and Disorders
- Thyroid Cancer Diagnosis and Treatment
- Metabolism, Diabetes, and Cancer
- Diabetic Foot Ulcer Assessment and Management
- Tumors and Oncological Cases
- Bioinformatics and Genomic Networks
Affiliated Hospital of North Sichuan Medical College
2024
Capital Medical University
2013-2021
Beijing Shijitan Hospital
2005-2021
Background . Long noncoding RNAs (lncRNAs) were recently shown to have potential in the diagnosis and prognosis for numerous cancers. lncRNA GAS8-AS1 is decreased papillary thyroid cancer (PTC) tissue, but its plasma expression clinical value patients with PTC remain unknown. Materials Methods We investigated profile of 97 39 nodular goiter by quantitative real-time polymerase chain reaction. Results was downregulated comparison those goiters (<mml:math...
Ghrelin, a newly discovered bioactive peptide, initially was identified as strong stimulant for the release of growth hormone (GH) and that has improved cardiac function in patients suffering from end-stage chronic heart failure. Increasing evidence demonstrated ghrelin may have myocardial protective effects. However, role pathogenesis cardiovascular diseases remains unclear. In this study, an vivo model rat calcification induced by vitamin D3 nicotine used to study possible mechanism...
The relationship between Type 2 Diabetes Mellitus(T2DM) and cancer risk has been investigated for more than a decade. Many types of were confirmed to be related with T2DM. aim this study is identify the T2DM prevalence long-term survivals Thyroid Carcinoma(TC) using propensity score matching. In present study, 1658 thyroid nodule patients who diagnosis in Beijing Shijitan hospital divided into two groups: TC group (N = 455, 27.4%), benign nodule(BTN) 1203, 73.6%). Propensity scores analyses...
To explore the impact of gender on presentation primary hyperparathyroidism (PHPT), clinical data 150 histopathologically proven PHPT patients were collected and retrospectively analyzed. Most (72.0%) parathyroid adenoma (PA), 9.3% them carcinoma (PC). In PA patients, albumin-corrected serum calcium levels (TASC) lower in women than men [ (2.84±0.28) mmol/L vs. (3.03±0.34) mmol/L, P=0.006]. all subjects, urea nitrogen, creatinine, uric acid men. Bone pain was more frequent over 50 years old...
To explore the characteristics of SLCO1B1/SLCO1B3 gene variants among children with Rotor syndrome (RS).
Objective: To evaluate the clinical characteristics and preoperative predictive factors in patients with parathyroid carcinoma. Methods: From January 2010 to December 2016, 150 pathologically biochemically confirmed primary hyperparathyroidism were enrolled this study. The data reviewed define 28 cases of hyperplasia, 14 carcinoma (PC), 108 adenoma (PA). between PC PA group compared analyzed explore for PC. Results: Patients significantly younger than those (47.9±13.9 vs 57.2±14.6 years,...
Background Dysregulated lncRNA score and PVT1 expression may be involved in cancer. However, relationships of lncRNAs with hyperparathyroidism parathyroid cancer (PC) diagnosis remain mysterious. Methods Using quantitative real-time polymerase chain reaction (RT-qPCR), profile was evaluated 57 patients primary hyperparathyroidism, including 11 46 adenoma (PA). Results Higher levels were associated increased serum calcium level after water ingestion PC risk ( P < 0.05). Accordingly,...
The prevalence of asymptomatic primary hyperparathyroidism (PHPT) in China is lower than that European and American countries the study about characteristics PHPT was rare China. This aims to explore PHPT.
Abstract Background: Tumor-specific immunity of insulin-like growth factor binding protein-2 (IGFBP-2) has been reported in several cancers. We aimed to assess the role serum IGFBP-2 antibodies (IGFBP-2-Abs) early cancer detection. Patients and Methods: Glioma colorectal carcinoma (CRC) were used as models. Serum IGFBP-2-Abs measured 260 tumor patients (145 gliomas, 45 polyps, 70 CRCs) 141 controls. Receiver operating characteristic curves applied. Results: IGFBP-2-Ab levels significantly...
2036 Background: Insulin-like growth factor binding protein-2 (IGFBP-2) has been suggested to be related the initiation and progression of gliomas. An elevated IGFBP-2 level in tumor tissue was found glioblastoma multiforme (GBM), most malignant form gliomas, associated with shortened survival GBM patients. To investigate a possibility as plasma surrogate marker for clinical outcomes glioma patients, we retrospectively examined patients different grades before surgery its association...