- COVID-19 Clinical Research Studies
- Urinary Bladder and Prostate Research
- Cardiac Ischemia and Reperfusion
- Pelvic floor disorders treatments
- Inflammatory Biomarkers in Disease Prognosis
- Neonatal Health and Biochemistry
- Body Composition Measurement Techniques
- Apelin-related biomedical research
- Vitamin C and Antioxidants Research
- COVID-19 Impact on Reproduction
- Urinary Tract Infections Management
- Urological Disorders and Treatments
- Medical Education and Admissions
- Drug-Induced Hepatotoxicity and Protection
- Sulfur Compounds in Biology
- Clinical Laboratory Practices and Quality Control
- Folate and B Vitamins Research
- Long-Term Effects of COVID-19
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Sperm and Testicular Function
- Biomarkers in Disease Mechanisms
- Alzheimer's disease research and treatments
- Lipid metabolism and disorders
- Adipokines, Inflammation, and Metabolic Diseases
- Cardiovascular Function and Risk Factors
Pamukkale University
2015-2025
State Hospital
2022
Background and Objectives: This study aimed to determine the relationship between miRNAs overactive bladder (OAB). We also reveal diagnostic properties of their potential predict responses therapy. Materials Methods: The included 60 patients with OAB as treatment group healthy individuals control group. blood levels 15 in both groups were determined using PCR. Also, high values identified receiver operating characteristic (ROC) curves. Finally, Turkish-validated questionnaire form was filled...
Abstract A nationwide multicenter study was organized to establish reference intervals (RIs) in the Turkish population for 25 commonly tested biochemical analytes and explore sources of variation values, including regionality. Blood samples were collected 28 laboratories from seven regions (≥400 samples/region, 3066 all). The sera collectively analyzed Uludag University Bursa using Abbott reagents analyzer. Reference materials used standardization test results. After secondary exclusion...
To assess the association between serum lipids and diabetic retinopathy (DR).Sixty-one patients without retinopathy(NDR), 55 with non-proliferative retinopathy(NPDR) 75 proliferative (PDR) according to ETDRS grading scale were enrolled in this study. Total cholesterol, high density lipoprotein (HDL), low (LDL), very (VLDL) triglyceride values compared groups.The groups well-balanced terms of age gender (P=0.071, P=0.265 respectively). The mean HbA1c significantly lower NDR group than NPDR...
The main objective of this study was to define urinary biomarkers that can predict the severity overactive bladder and detect patients who would benefit most from treatment.Patients with an OAB diagnosis healthy controls were included in study. A diary a validated questionnaire given all patients. In group, solifenacin 5 mg daily for 1 month. Urine samples taken before treatment after first month both groups BDNF, NGF, GAG, MCP-1 levels measured.A total 45 age-matched included. BDNF/Cre,...
The aim of this study was to find out the predictive role serum and urinary carbohydrate antigen 19-9 levels in benign hydronephrosis whether these are helpful for differentiation complete or partial obstruction.Fifty-four patients with, 23 without, were enrolled study. Serum determined by chemiluminescence enzyme immunometric assay method correlated with clinical factors.The mean (P < 0.0001) creatinine 0.008) significantly higher group than control group. There significant correlation...
Although there are many available data about renal involvement in patients with beta thalassemia major (TM), the changes functions of other types, such as intermedia (TI) and minor (TMin), were reported less. Therefore, we aimed to evaluate tubular glomerular three types thalassemia.This prospective case-control study was conducted on 118 beta-thalassemia (49 TM, 18 TI 51 TMin) healthy controls. Glomerular [estimated filtration rate (GFR), serum cystatin C urinary protein creatinine ratio]...
A low-grade systemic inflammation is concomitant in diabetes. There a pathophysiological relation between gestational diabetes mellitus and type 2 mellitus, which was further supported by significantly elevated risk of women with history previous mellitus. We investigated the expressed as C-reactive protein non-obese pregnant women. This study included 20 30 without control group. The body mass index all subjects were < 25 kg/m2. During 26-28 weeks 100-g oral glucose tolerance test performed...
The role of Ghrelin, also known as the appetite hormone, is not fully explained in development morbid obesity. Plasma Ghrelin level low obese and high slim subjects. Ghrelin-expressing cells were investigated histopathologically stomach patients this study. Tissue expression was compared with various parameters such distribution endocrine cells, age, gender, body mass index, preoperative plasma presence accompanying diseases.The study included 33 morbidly patients, 8 non-obese control...
Abstract Aims It has been demonstrated that there are abundant stable microRNAs (miRNAs) in plasma, which is potentially disease‐specific. Adrenergic and muscarinic pathways play an important role voiding physiology. Alterations the levels of miRNAs thought to influence regulation these at molecular level. The aim this study was investigate relationship with overactive bladder pathogenesis provide a new perspective treatment approaches. Methods This included patients (OAB) diagnosis healthy...
Electroconvulsive therapy (ECT) is used in the treatment of many psychiatric diseases and this may be effective on antioxidant defence system. In study, we aimed to evaluate effects ECT oxidative stress.Fourteen major depression, 11 schizophrenia 8 bipolar affective disorder patients diagnosed received treatment, 37 healthy volunteers enrolled study. was applied all patients. Before ECT, after first last ECTs, serum samples were obtained. Serum total status (TAS), oxidant (TOS), calculated...
The aim of this study was to investigate and compare the effects udenafil mannitol in an experimental renal ischemia-reperfusion (I/R) injury model.A total 64 female Wister Albino rats were used. Right nephrectomy performed all groups. In control group; I/R not performed. left pedicle clamped for 45 minutes then underwent 60 24 hours reperfusion. 1 mL 20% given intravenously 15 before clamping. 10-mg/kg orally hour Creatinine (Cr), blood urea nitrogen (BUN), Cr clearance, malondialdehyde,...