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Contact & Profiles
A5081196238
Research Areas
- Immunotherapy and Immune Responses
- HIV Research and Treatment
- T-cell and B-cell Immunology
Emory National Primate Research Center
2021
HIV associated immune activation (IA) is with increased morbidity in people living (PLWH) on antiretroviral therapy, and remains a barrier for strategies aimed at reducing the reservoir. The underlying mechanisms of IA have not been definitively elucidated, however, persistent production Type I IFNs expression ISGs considered to be one primary factors. Plasmacytoid DCs (pDCs) are major producer IFN during viral infections, highly immunomodulatory acute SIV infection, however their role...
10.1371/journal.ppat.1009674
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PLoS Pathogens
2021-06-28
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