A5034362250- Mesenchymal stem cell research
- Neutropenia and Cancer Infections
- Protein Degradation and Inhibitors
- RNA Interference and Gene Delivery
- Bacterial Identification and Susceptibility Testing
- Histone Deacetylase Inhibitors Research
- MicroRNA in disease regulation
- Hematopoietic Stem Cell Transplantation
- Chemotherapy-induced cardiotoxicity and mitigation
- Hemoglobinopathies and Related Disorders
- Neurogenetic and Muscular Disorders Research
- Cancer-related gene regulation
- SARS-CoV-2 and COVID-19 Research
- Pharmacological Effects and Toxicity Studies
- Circular RNAs in diseases
- Monoclonal and Polyclonal Antibodies Research
- Dielectric materials and actuators
- Intensive Care Unit Cognitive Disorders
- Vitamin C and Antioxidants Research
- Antifungal resistance and susceptibility
- Fungal Infections and Studies
- Cancer Mechanisms and Therapy
- Pneumocystis jirovecii pneumonia detection and treatment
- Cardiac Ischemia and Reperfusion
- Infections and bacterial resistance
Fujian Medical University
2017-2024
First Affiliated Hospital of Fujian Medical University
2024
Central Hospital of Zibo
2020-2024
Union Hospital
2017-2023
Huazhong University of Science and Technology
2009-2011
Tongji Hospital
2011
Background: Bloodstream infection (BSI) is a common and serious complication after patients with hematologic malignancies (HM) receiving chemotherapy.This study examined real-world data seeking to characterize HM BSI identify risk factors for emergence mortality.Methods: We retrospectively analyzed the pathogenic epidemiology, antibiotic resistance, in single-center cohort including 3014 consecutive chemotherapy between 2013 2016.Results of epidemiology were validated via comparison...
// Yan-Ling Zeng 1, 2, * , Hao Zheng Qiu-Ru Chen Xiao-Hong Yuan 1 Jin-Hua Ren Xiao-Feng Luo Ping Zhe-Yao Lin 2 Shao-Zhen Xue-Qiong Wu Min Xiao Yong-Quan Zhi-Zhe Jian-Da Hu Ting Yang Department of Hematology, Fujian Institute Provincial Key Laboratory Medical University Union Hospital, Fuzhou 350001, P. R. China Affiliated Nanping First Hospital University, 353000, These authors are regarded as co-first author Correspondence to: Yang, email: yang.hopeting@gmail.com Hu, drjiandahu@163.com...
Abstract Multiple myeloma (MM) is an incurable hematological malignancy, and the number of MM patients increasing year by year. Zinc finger protein 655 (ZNF655) has been shown to regulate various biological processes implicated in progression many diseases. However, roles ZNF655 remains unclear. In this study, we aimed explore effects on detecting alteration phenotypes tumorigenesis induced knockdown MM. The expression level was clarified real‐time quantitative polymerase chain reaction...
Death-associated protein kinase 1 <i>(DAPK1)</i>, a proapoptotic serine/threonine kinase, is candidate tumor suppressor gene. We studied the methylation status of promoter region <i>DAPK1</i> gene and expression in 78 bone marrow samples from untreated patients with myelodysplastic syndrome (MDS) by PCR Western blot analysis. Hypermethylation was present 42.3% (33 78) MDS specimens significantly correlated loss mRNA (p < 0.01). There were no significant differences...
The present study aimed to establish an induced pluripotent stem cell (iPSC) line from acute myelogenous leukemia (AML) cells in vitro and identify their biological characteristics.Cells the AML-infiltrated skin M6 patient were infected with a lentivirus carrying OCT4, SOX2, KLF4 C-MYC induce iPSCs. characteristics of iPSCs confirmed by alkaline phosphatase (ALP) staining. proliferation ability was detected CCK-8 assay. expression pluripotency markers measured immunostaining, cell-related...
Bone marrow mesenchymal stem cells (BMSCs) have been extensively investigated from a perspective on cardiac regeneration therapy. The current study aimed to investigate the protective effect conferred by BMSCs in subacute myocardial injury, and identify an appropriate BMSC reinfusion time.BMSCs were isolated human bone blood. Daunorubicin (DNR)-induced models subsequently established. rats with DNR-induced injury injected dexrazoxane (DZR) and/or at varying time points, after which function...
Cytomegalovirus reactivation (CMVr) and bloodstream infections (BSI) are the most common infectious complications in patients after allogeneic haematopoietic stem cell transplantation (allo-HSCT). Both associated with great high morbidity whilst BSI is leading cause of mortality. This retrospective study evaluated incidence CMVr BSI, identified risk factors, assessed their impact on survival allo-HSCT recipients during first 100 days transplantation. The comprised 500 who were CMV...
Abstract Rationale: Rituximab is a monoclonal antibody directed against B cells and first-line agent for the treatment of cell lymphoma second-line idiopathic thrombocytopenic purpura (ITP). It has also been used several other autoimmune diseases. Epidermolysis bullosa acquisita (EBA) never reported as an adverse effect resulted from rituximab therapy. Patient concerns: A 54-year-old female presented with relapse ITP around eight months. She was treated rituximab. Intramuscular...
<b><i>Objective:</i></b> The study aimed to explore the effects of blood purification (BP) on serum levels inflammatory cytokines and cardiac function in a rat model sepsis. <b><i>Methods:</i></b> A sepsis was established by cecal ligation puncture. All rats were divided into normal control, sham operation, model, treatment, BP treatment groups. Cardiac functions, cytokines, myocardial enzymes, pathological score muscle tissue, apoptosis each...
Abstract Case Description Fungal vertebral osteomylitis is a rare disease that difficult to diagnosis and cure. Because the early specific clinical manifestations of this are few atypical, it often missed or misdiagnosed, resulting in treatment delay aggravation disease. Objective To report case cryptococcal osteomyelitis resembles metastatic tumor happened an immunecompromised patient with history mantle cell lymphoma review cases reported literature. Study Design Based on imaging studies,...