Lin Zhu

ORCID: 0000-0002-0748-1025
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About
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Research Areas
  • Nanoparticle-Based Drug Delivery
  • Gold and Silver Nanoparticles Synthesis and Applications
  • Nanocluster Synthesis and Applications
  • Advanced Nanomaterials in Catalysis
  • Nanoplatforms for cancer theranostics
  • Advanced biosensing and bioanalysis techniques
  • Quantum Dots Synthesis And Properties
  • Graphene and Nanomaterials Applications
  • Carbon and Quantum Dots Applications
  • Obstructive Sleep Apnea Research
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Surgical site infection prevention
  • Protein Interaction Studies and Fluorescence Analysis
  • Pressure Ulcer Prevention and Management
  • Iron oxide chemistry and applications
  • Nanoparticles: synthesis and applications
  • Neonatal Respiratory Health Research
  • Polyoxometalates: Synthesis and Applications
  • Intraoperative Neuromonitoring and Anesthetic Effects
  • Fiber-reinforced polymer composites
  • biodegradable polymer synthesis and properties
  • Reproductive tract infections research
  • Enzyme function and inhibition
  • Fungal Biology and Applications
  • Inflammation biomarkers and pathways

Hunan Agricultural University
2024

First Affiliated Hospital of Xiamen University
2022

Qingdao Agricultural University
2022

Sichuan Cancer Hospital
2017-2021

University of Electronic Science and Technology of China
2021

Universität Hamburg
2019-2021

Fuzhou University
2021

Qingdao University
2020-2021

Affiliated Hospital of Qingdao University
2020-2021

Vironova (Sweden)
2021

Synthesis, characterization, and applications of colloidal nanoparticles have been a prominent topic current research interests within the last two decades. Available reports in literature that describe synthesis are abundant with various degrees reproducibility simplicity. Moreover, different methods for characterization nanoparticle's basic properties employed, resulting conflicting results many cases. Herein, we "in detail" selected standard protocols synthesis, purification, types...

10.1021/acs.chemmater.6b04738 article EN Chemistry of Materials 2016-12-12

Nano-drugs based on nanoparticles (NP) or nano-assemblies as carriers of the active pharmaceutical ingredient (API) are often expected to perform better compared conventional dosage forms. Maximum realization this potential though requires optimization multiple physico-chemical, including structural and morphological, parameters. Meaningful distributions these parameters derived from sufficient populations individual NPs rather than ensemble desirable for task, provided that relevant...

10.3390/pharmaceutics13010123 article EN cc-by Pharmaceutics 2021-01-19

A laboratory class was developed and evaluated to illustrate the synthesis of metal nanoclusters (NCs) explain their photoluminescence properties for case silver. The described experiment employs a synthetic protocol that consists two sequential phases in single reaction pot: reduction silver ions into plasmonic nanoparticles (NPs) (bottom-up), followed by etching formed NPs ultrasmall atomically precise fluorescent NCs (top-down), Ag29(DHLA)12 (DHLA: dihydrolipoic acid). UV–vis absorption...

10.1021/acs.jchemed.9b00342 article EN Journal of Chemical Education 2019-11-05

This study demonstrate that the AuNP–HSA corona could penetrate cell membranes and companied by substantial membrane disruption. However, ultrasmall AuNPs can be internalized cells without destruction of membranes.

10.1039/c8ra10049g article EN cc-by-nc RSC Advances 2019-01-01

Inorganic iron oxide nanoparticle cores as model systems for inorganic nanoparticles were coated with shells of amphiphilic polymers, to which organic fluorophores linked different conjugation chemistries, including 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide (EDC) chemistry and two types “click chemistry”. The nanoparticle-dye conjugates exposed enzymes/enzyme mixtures in order investigate potential enzymatic degradation the fluorophore-modified polymer shell. release dyes fragments upon...

10.3390/ijms20040935 article EN International Journal of Molecular Sciences 2019-02-21

11-Mercaptoundecanoic acid-protected gold nanoclusters (Au@MUA NCs) were synthesized and investigated as a model to understand the photoluminescence (PL) properties of water-soluble, structurally unknown Au NCs. Surface engineering, including ligand exchange where length alkane chain was changed, conjugation charged terminal carboxyl group ligands blocked, effects external chemical reducing oxidizing agents, carried out. PL profiles monitored reveal impact surface engineering on PL. We found...

10.1021/acsanm.1c00404 article EN ACS Applied Nano Materials 2021-02-25

Recently, studies on the application of light-responsive semiconductor nanomaterials for photodynamic therapy (PDT) non-solid tumors have attracted tremendous attention. Herein, 6.98 nm Ag2S nanoparticles (Ag2S NPs) with excellent aqueous dispersibility, stability, and biocompatibility were synthesized by a facile strategy without any post-modification. In vitro indicated that NPs could significantly inhibit growth human lymphoma cells (Raji cells) compared hepatoma carcinoma (Hep G2 under...

10.1039/c9ra05432d article EN cc-by-nc RSC Advances 2019-01-01

Abstract The “cyborg cells”, living cells with built-in nanoscaffolds, which could integrate the biological function of functionality nanomaterials, have been rarely explored. Here we report a method to construct erythrocytes” through in situ reaction exogenous calcium and carbonate ions generate nanodots inside erythrocytes. intracellular combined proteins are hidden under membrane erythrocytes, can restrict migration unexpected accumulation body, improving biosecurity nanodots. Most...

10.1038/s42004-019-0199-z article EN cc-by Communications Chemistry 2019-09-06

The strategic implementation of using a core-substituted naphthalene diimide derivative to electropolymerize an ionized polymer for better electrochromic performance is proposed.

10.1039/d1tc04446j article EN Journal of Materials Chemistry C 2021-01-01

Abstract Currently, the studies about photodynamic therapy (PDT) of human cancers have made considerable progress and attracted tremendous attention. The existing photosensitizers used for PDT are mainly organic compounds. In order to enhance their photosensitizing efficacy, some reported hybrid consisting inorganic quantum dots (QDs) photosensitizers. Herein, a new type photosensitizer sole semiconductor CdTe QDs with good excellent water dispersibility, stability is reported. prepared...

10.1002/ppsc.201600413 article EN Particle & Particle Systems Characterization 2017-07-25

Amorphous and crystalline copper sulfide quantum dots (QDs) with good water-solubility were obtained controllably by a novel hydrolysis strategy. These QDs exhibited anti-proliferation activities on cancer cells rather than normal the biological are related to their polymorphs. Our study opens up new avenues for fabricating stable water-soluble metal QDs.

10.1039/c5tb00960j article EN Journal of Materials Chemistry B 2015-01-01

Organisms invading root canal systems result in serious pulpal and periapical disease. To eliminate microorganisms restrain secondary infections, dental materials with antibacterial properties are urgently needed endodontics. Magnesium is considered as a promising biodegradable biocompatible implant material. However, there barely researches about its application endodontic therapy. This work investigated the vitro efficacy of magnesium powder against Enterococcus faecalis Candida albicans...

10.1016/j.pnsc.2014.09.003 article EN cc-by-nc-nd Progress in Natural Science Materials International 2014-10-01

Studies on distinctive performances and novel applications of amorphous inorganic nanomaterials are becoming attractive. Herein, Ag2 S crystalline nanodots (ANDs CNDs) prepared via facile methods. In vitro in vivo studies indicate that ANDs, rather than CNDs, can induce the self-destruction tumors, which be attributed to their chemical properties, e.g., higher electrochemical active surface area lower redox potential well matching with reaction requirement tumor microenvironment. ANDs...

10.1002/smll.201902945 article EN publisher-specific-oa Small 2019-09-18

Cerebroprotein hydrolysate-I (CH-I),a mixture of peptides extracted from porcine brain tissue,has shown a neuroprotective effect, but its role in senescence is unclear. In the present study, we established model PC12 cells and mice to investigate effect CH-I on via JAK2/STAT3 pathway. The results showed that could improve cell viability, inhibit apoptosis cells, reduce senescence-positive induced by D-galactose.

10.1002/fsn3.2333 article EN cc-by Food Science & Nutrition 2021-05-17

Chlamydia trachomatis (Ct) genital infection is the most common sexually transmitted disease (STD) in China and US. The morbidity of Ct has increased from 32.48/100,000 2008 to 37.18/100,000 2015.[1] major areas infections are concentrated Zhujiang Delta, Changjiang Minjiang Area, West China. In these areas, highest incidence reaches 615.99/100,000 citizens. US, there 1,441,789 reported Ct, which include 627.2 females 278.4 males per 100,000 population. It now prevalent STD, with its rate...

10.4103/0366-6999.219159 article EN cc-by-nc-nd Chinese Medical Journal 2017-12-05

Objective This prospective study was performed to explore the change in sacrococcygeal pressure during an operation under general anesthesia supine position and identify correlation between injury body mass index. Methods involved 99 patients who underwent anesthesia. Sacrococcygeal measured recorded at seven time points: before anesthesia, 5 minutes after 1, 2, 3, 4, hours beginning of operation. The each point compared, factors affecting were analyzed. Results analysis showed that...

10.1177/0300060520984595 article EN cc-by-nc Journal of International Medical Research 2021-07-01

ADVERTISEMENT RETURN TO ISSUEPREVAddition/CorrectionNEXTORIGINAL ARTICLEThis notice is a correctionCorrection to Selected Standard Protocols for the Synthesis, Phase Transfer, and Characterization of Inorganic Colloidal NanoparticlesJonas HühnJonas HühnMore by Jonas Hühn, Carolina Carrillo-CarrionCarolina Carrillo-CarrionMore Carrillo-Carrion, Mahmoud G. SolimanMahmoud SolimanMore Soliman, Christian PfeifferChristian PfeifferMore Pfeiffer, Daniel ValdeperezDaniel ValdeperezMore...

10.1021/acs.chemmater.1c01764 article EN Chemistry of Materials 2021-06-11

BACKGROUND: Surgical delay and ischemic preconditioning have been traditionally used to precondition flaps render more vascular resistant changes in their microcirculation. Negative pressure wound therapy (NPWT) has extensively clinical practice associated with angiogenesis accelerated healing. This experimental model evaluated topical negative as a mechanism for non-invasive perforator flap microvascularity perfusion. METHODS: Two gluteal (matched control intervention) were designed on...

10.1097/01.gox.0000502939.29596.41 article EN cc-by-nc-nd Plastic & Reconstructive Surgery Global Open 2016-09-01
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