A5018430553- Dementia and Cognitive Impairment Research
- Health, Environment, Cognitive Aging
- Health Policy Implementation Science
- Family and Patient Care in Intensive Care Units
- Cardiac Health and Mental Health
- Cultural Competency in Health Care
- Diabetes Management and Education
- Cardiovascular Health and Risk Factors
- Biosimilars and Bioanalytical Methods
- Mobile Health and mHealth Applications
- SARS-CoV-2 detection and testing
- Thyroid Disorders and Treatments
- Ethics in Clinical Research
- Cannabis and Cannabinoid Research
- Education and Communication Studies
- Dental Education, Practice, Research
- Sleep and related disorders
- Food Security and Health in Diverse Populations
- Axon Guidance and Neuronal Signaling
- Diabetes Treatment and Management
- Palliative Care and End-of-Life Issues
- Apelin-related biomedical research
- Biomarkers in Disease Mechanisms
- Sleep and Wakefulness Research
- Technology Use by Older Adults
Ain Shams University
2024-2025
Toronto General Hospital
2024
University Health Network
2024
University of Toronto
2019-2024
Toronto General Hospital Research Institute
2024
Ontario Brain Institute
2023-2024
Krembil Brain Institute
2023-2024
SickKids Foundation
2022-2024
Public Health Ontario
2024
Toronto Western Hospital
2024
The burden of noncommunicable chronic diseases has relevant and negative consequences to persons, health care systems, economies worldwide. Chronic are the leading cause disability mortality responsible for 90% expenditure. most common diabetes mellitus (DM), cardiovascular disease, cerebrovascular disease (stroke vascular cognitive impairment). Modifiable risk factors (MRFs) these conditions include hypertension, hyperlipidemia, smoking, poor diet, low-physical activity; with hypertension...
Introduction The 21-point Brain Care Score (BCS) was developed through a modified Delphi process in partnership with practitioners and patients to promote behavior changes lifestyle choices order sustainably reduce the risk of dementia stroke. We aimed assess associations BCS incident Methods derived from United Kingdom Biobank (UKB) baseline evaluation for participants aged 40–69 years, recruited between 2006–2010. Associations subsequent stroke were estimated using Cox proportional hazard...
Abstract Background Dendritic cells, T lymphocytes, B neutrophils, eosinophils, and macrophages all express the semaphorin 4D (SEMA4D) protein, which is involved in signal transduction, immunological reaction, as well regulation of angiogenesis. Moreover, it was suggested that SEMA4D acute lymphoblastic leukemia cells can alter cell cycle hinder apoptosis besides increasing ability to grow invade other tissues. Aim To assess serum level before after induction chemotherapy adult Egyptian...
Patient profiles have changed from shifting demographics, globalization and immigration. Such changes highlight the need to educate train healthcare trainees providers (HCPs) on provision of person-centred care through an equity, diversity inclusion (EDI) approach. Simulation pedagogy has potential be a useful impactful teaching learning approach for EDI. The purpose this review was explore summarize current literature level integration state EDI in clinical simulation within education,...
Abstract Background Hashimoto's thyroiditis is one of the most common autoimmune disorders. Patients typically present with nonspecific symptoms, such as fatigue, weight gain, cold intolerance, constipation, and dry skin, which can significantly impair patients' quality life. Conventional treatments focus on hormone replacement therapy for hypothyroidism, but emerging research suggests dietary interventions, like Mediterranean diet, may provide added benefits. Many patients continue to...
Background: The importance of adapting evidence-based health interventions to enhance their congruence with the beliefs ethno-cultural communities is well recognized. Although a systematic cultural adaptation process available, it lacks specific instructions on how adapt so that they are aligned beliefs. In this paper, we present an integrated strategy operationalizes by describing practical align Methods: integrates concept and intervention mapping, uses mixed methods for gathering data...
The use of electronic documentation systems (EDS) has the potential to ensure timely, up-to-date and comprehensive patient health-related information is available accessible nurses regardless their physical location. Despite benefits EDS, nurses' low intention such well documented, which may predict behavioural usage. Further, limited knowledge exists about EDS in context home care. aim study was examine factors that influence using care practice. conceptual model framing this adapted from...
Introduction: The 21-point Brain Care Score (BCS), developed via a modified Delphi process with practitioners and patients, is novel instrument designed to motivate behavioral lifestyle changes, ultimately aiming decrease incidence of dementia stroke (Fig 1). Whether or not BCS components are associated longitudinal changes in mood disorders clear. For this study, we tested the hypothesis that also significantly correlates late-life depression UK Biobank (UKB). Design / Methods: was derived...
Background Stroke incidence among young adults of working age (under 65 years age) has significantly increased in the past decade, with major individual, social, and economic implications. There is a paucity research exploring needs this patient population. This study assessed: (1) adult stroke patients' physical, psychological, occupational functioning health-related quality life (HRQoL); (2) post-stroke care preferences using patient-reported outcome measures (PROMs), attention to gender...
The 21-point Brain Care Score (BCS) is a novel tool designed to motivate individuals and care providers take action reduce the risk of stroke dementia by encouraging lifestyle changes. Given that late-life depression increasingly recognized share factors with dementia, an important clinical endpoint for brain health, we tested hypothesis higher BCS associated reduced incidence future depression. Additionally, examined its association health composite outcome comprising stroke,
To investigate associations between health-related behaviors as measured using the Brain Care Score (BCS) and neuroimaging markers of white matter injury.
Purpose: The purpose of this study was twofold: to examine the acceptability and preference for two behavioral therapies, identify factors persons with chronic insomnia take into account when choosing treatment. Methods: data were obtained in a large trial evaluating effects Stimulus Control Sleep Restriction therapies. Prior treatment, participants completed treatment (TAP) questionnaire, which described Therapy requested rate each option before one management insomnia. Open-ended questions...
The COVID-19 pandemic has strained health systems world wide. In our region, surging numbers of critically ill adult patients demanded urgent system-wide responses. During the peak pandemic, Pediatric Intensive Care Unit (PICU) team redesigned existing educational resources and processes care to ensure for first time in hospital's history.Describe experiences impacts rapidly initiated Adult Program on providers (HCP) family members. Havelock's Theory Change framed examination participant...
The 21-point Brain Care Score (BCS) is a novel tool designed to motivate individuals and care providers take action reduce the risk of stroke dementia by motivating lifestyle changes (Fig 1). In this study we aimed assess if BCS also associated with brain on MRI in people who have not yet developed or stroke. Methods: This was conducted within substudy longitudinal cohort UK Biobank. assessed neuroimaging markers included: volume, white matter hyperintensities (WMH) fractional anisotropy...