A5039944332- Rheumatoid Arthritis Research and Therapies
- Musculoskeletal synovial abnormalities and treatments
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Systemic Lupus Erythematosus Research
- Inflammatory Myopathies and Dermatomyositis
- Shoulder Injury and Treatment
- Systemic Sclerosis and Related Diseases
- Orthopedic Surgery and Rehabilitation
- Orthopedic Infections and Treatments
- Musculoskeletal Disorders and Rehabilitation
- Vasculitis and related conditions
- Autoimmune and Inflammatory Disorders Research
- Muscle and Compartmental Disorders
- Hip disorders and treatments
- Shoulder and Clavicle Injuries
- Elbow and Forearm Trauma Treatment
- Salivary Gland Disorders and Functions
- Liver Diseases and Immunity
- Nutrition and Health in Aging
- Liver Disease Diagnosis and Treatment
- Sarcoidosis and Beryllium Toxicity Research
- Nietzsche, Schopenhauer, and Hegel
- Traumatic Ocular and Foreign Body Injuries
- Single-cell and spatial transcriptomics
- Cardiomyopathy and Myosin Studies
Hospital de Santa Maria
2001-2024
Centro Hospitalar Lisboa Norte
2011-2024
University of Lisbon
2016-2024
Instituto de Medicina Molecular João Lobo Antunes
2021
University of Concepción
2020
Hospital de Egas Moniz
2017
Universidade de São Paulo
2017
Objectives To assess the sensitivity to change of ultrasound halo features and their association with disease activity glucocorticoid (GC) treatment in patients newly diagnosed giant cell arteritis (GCA). Methods Prospective study ultrasound-confirmed GCA who underwent serial assessments temporal artery (TA) axillary (AX) at fixed time points. The number segments maximum intima–media thickness (IMT) was recorded. Time points which >80% were assessed considered for analysis. Halo...
A low fermentable oligo-di-mono-saccharides and polyols (FODMAP) diet is a balanced therapy for fi bromyalgia with nutritional symptomatic benefi ts Una dieta baja en oligo-, di-y monosacáridos (FODMAPs) es un tratamiento adecuado para
In this study, we optimized the dissociation of synovial tissue biopsies for single-cell omics studies and created a atlas human synovium in inflammatory arthritis. The protocol allowed consistent isolation highly viable cells from tiny fresh biopsies, minimizing biopsy drop-out rate. scRNA-seq contained over 100,000 unsorted 25 tissues affected by arthritis, including 16 structural, 11 lymphoid, 15 myeloid cell clusters. This map expanded diversity types/states, detected neutrophils,...
The coronavirus disease 2019 (COVID-19) pandemic has come with many challenges for healthcare providers and patients alike. In addition to the direct burden it placed on societies health systems, had a significant impact in care of chronic diseases, as resources were deployed fight crisis, major travel social restrictions adopted. field rheumatology, this required notable efforts from departments clinicians adapt novel status quo assure follow-up rheumatic musculoskeletal diseases. present...
Objective To study the efficacy, tolerability, safety, and sampling variation of ultrasound (US)–guided synovial biopsies performed in clinical practice research. Methods We included all patients who had a US‐guided needle biopsy from November 2013 to January 2018. Patients were evaluated for procedure safety tolerability. Usefulness was considered based on contribution achieving proposed aims. analyzed samples presence quality tissue, synovitis score/grade, pathotype. Variation across...
Stress fractures are common in young and active individuals, associated with aggressive or repetitive physical activity their early detection is fundamental to optimise patient care, decrease complications avoid unnecessary exams. Currently, magnetic resonance imaging the standard of care for detecting these lesions. Recently, ultrasound has been getting an increasing interest stress fractures. In this article, we describe a clinical case that involved second metatarsal fracture diagnosed by...
Background: Endometrosis is a multifactorial disease and one of the main causes infertility in mares, its etiology pathogenesis are not completely understood. It defined as peri glandular and/or stromal endometrial fibrosis with alterations. Due to few clinical symptoms, besides anamnesis fertility data, endometrosis requires histological confirmation. The histo-morphology immune histochemical characteristics endometrium vary among individuals according progression. aim this research was...
OBJETIVO: caracterizar as manifestações clínicas, exócrinas e não exócrinas, de 74 pacientes com síndrome Sjögren primária (SSp). MÉTODOS: estudo retrospectivo dos SSp acordo os novos critérios americano-europeus 2002, seguidos no serviço reumatologia doenças ósseas metabólicas do Hospital Santa Maria (HSM) nos últimos 25 anos (média seguimento 7,7 anos). RESULTADOS: todos apresentaram doença exócrina epitélios superficiais, destaque para a xerostomia queratoconjuntivite seca. Doença órgãos...
<h3>Background</h3> There is a lack of adequate outcome measures treatment response in Knee Osteoarthritis (KOA). The role Ultrasonography (US) the management inflammatory articular and periarticular diseases well established, but it has been less extensively used OA. <h3>Objectives</h3> To develop new high-resolution US protocol for assessment structural changes primary KOA to evaluate its inter-observer reliability. <h3>Methods</h3> A scanning was developed by consensus among 3 senior...