A5025676060- Head and Neck Cancer Studies
- Head and Neck Surgical Oncology
- Thyroid Cancer Diagnosis and Treatment
- Salivary Gland Tumors Diagnosis and Treatment
- Economic and Financial Impacts of Cancer
- COVID-19 and healthcare impacts
- Reproductive Physiology in Livestock
- Cancer Diagnosis and Treatment
- Global Cancer Incidence and Screening
- Cervical Cancer and HPV Research
- Genetic and phenotypic traits in livestock
- Tracheal and airway disorders
- Esophageal Cancer Research and Treatment
- Ear and Head Tumors
- COVID-19 Clinical Research Studies
- BRCA gene mutations in cancer
- Livestock Management and Performance Improvement
- Tumors and Oncological Cases
- Anesthesia and Pain Management
- Thyroid and Parathyroid Surgery
- Opioid Use Disorder Treatment
- Cancer Genomics and Diagnostics
- Oral Health Pathology and Treatment
- Cardiac, Anesthesia and Surgical Outcomes
- Public Spaces through Art
Albert Einstein College of Medicine
2018-2024
Montefiore Medical Center
2018-2024
King's College London
2020-2023
Montefiore Health System
2023
University of Illinois Urbana-Champaign
2022
University of Illinois Chicago
2022
Mount Sinai Hospital
2022
The Bronx Defenders
2019-2022
Guru Gobind Singh Medical College and Hospital
2022
University of Cincinnati
2020-2021
Abstract Patients with cancer are presumed to be at increased risk from COVID-19 infection–related fatality due underlying malignancy, treatment-related immunosuppression, or comorbidities. A total of 218 COVID-19–positive patients March 18, 2020, April 8, a malignant diagnosis were identified. 61 (28%) died case rate (CFR) 37% (20/54) for hematologic malignancies and 25% (41/164) solid malignancies. Six 11 (55%) lung disease. Increased mortality was significantly associated older age,...
Large patient cohorts are necessary to validate the efficacy of transoral robotic surgery (TORS) in management head and neck cancer.To review oncologic outcomes TORS from a large multi-institutional collaboration identify predictors disease recurrence disease-specific mortality.A retrospective records 410 patients undergoing for laryngeal pharyngeal cancers January 1, 2007, through December 31, 2012, was performed. Pertinent data were obtained 11 participating medical institutions.Select...
BACKGROUND Extracapsular spread (ECS) in cervical lymph node metastases from head and neck squamous cell carcinoma (SCC) is regarded as an adverse prognostic factor often used to select patients who may benefit adjuvant therapy. The value of ECS was evaluated for with oropharyngeal SCC (OPC; known p16/human papillomavirus [HPV] status) the oral cavity (OCC). METHODS Disease‐specific survival (DSS) assessed among (n = 347, including 133 OPC 214 OCC). All were treated surgically between 1983...
Objective Neck masses are common in adults, but often the underlying etiology is not easily identifiable. While infections cause most of neck children, persistent adults neoplasms. Malignant neoplasms far exceed any other adult mass. Importantly, an asymptomatic mass may be initial or only clinically apparent manifestation head and cancer, such as squamous cell carcinoma (HNSCC), lymphoma, thyroid, salivary gland cancer. Evidence suggests that a patient should considered malignant until...
In 2% to 3% of patients with cancer metastatic cervical lymph nodes, a primary tumor will not be found despite exhaustive diagnostic efforts. The treatment for these includes lymphadenectomy followed by radiation areas increased risk harboring mucosal primary. Wide-field therapy increases the incidence xerostomia and dysphagia. Localizing has thus both therapeutic quality-of-life implications, allowing possible complete surgical excision, concentrated therapy, potential deintensification...
Delay in time to treatment initiation (TTI) can alter survival and oncologic outcomes. There is a need characterize these consequences identify risk factors reasons for delay, particularly underserved urban populations.To investigate the association of delayed with outcomes overall recurrence among patients head neck squamous cell carcinoma (HNSCC), analyze that are predictive initiation, specific initiation.Retrospective cohort study at an community-based academic center. Participants were...
The US Health and Human Services Pain Management Best Practices Inter-Agency Task Force initiated a public–private partnership which led to the publication of its report in 2019. emphasized need for individualized, multimodal, multidisciplinary approaches pain management that decrease over-reliance on opioids, increase access care, promote widespread education substance use disorders. specifically called specialty organizations work together develop evidence-based guidelines. In response...
Incremental delays in time to treatment initiation (TTI) have been shown cause a proportional, increased independent risk of disease-specific mortality for breast cancer, colorectal cancer (CRC), head and neck (HNC), non-small-cell lung (NSCLC), pancreatic cancer. Studies suggest that are associated with racial socioeconomic disparities. We evaluated associations between patient factors TTI identify those delay.This is retrospective cohort study at an urban community-based academic center...
Objectives/Hypothesis: To examine demographic, histologic, and survival trends of oral cavity oropharyngeal (OC/OP) squamous cell carcinoma (SCCA) patients over the past 3 decades. test hypothesis that decreased histologic differentiation increased disease-specific is related to a decline in smoking rates an percentage human papillomavirus (HPV)-related tumors. Study Design: Retrospective cohort analysis was done using Surveillance, Epidemiology, End-Results (SEER) database national cancer...
Objective Cancer of an unknown primary (CUP) squamous cell carcinoma metastatic to cervical lymph nodes is a challenging problem for the treating physician. Our aim determine if identification tumor associated with improved oncologic outcomes and/or characteristics including human papilloma virus (HPV) status. Study Design Retrospective, matched‐pairs analysis contrasting 2 cohorts based upon discovery lesion. Setting Tertiary teaching hospital. Subjects and Methods Records 136 patients...
Objectives/Hypothesis The number of trained otolaryngologists available is insufficient to supply current and projected US health care needs. goal this study was assess databases present accurate data on the otolaryngology workforce, examine methods for prediction future needs, explore potential issues with forecasting policy implementation based these predictions. Study Design Retrospective analysis research databases, public use files, claims data. Methods total practices in United States...
To determine posttreatment quality of life (QOL) in head and neck cancer patients, stratifying by human papillomavirus (HPV)/p16 status primary treatment modality.Retrospective study.One hundred seventy-seven patients (N=177) with squamous cell carcinoma known HPV/p16 were included. All completed at least one baseline or University Washington QOL survey. scores averaged compared across modality (surgical vs. nonsurgical). In the analysis, p16 was used as a surrogate marker for HPV.Of 177 80...
Objectives To examine opioid‐prescribing patterns after endocrine surgery. evaluate factors associated with postoperative pain and opioid use. Study Design Cross‐sectional. Setting Academic university health system. Subjects Methods The study sample included 209 patients who underwent total thyroidectomy, hemithyroidectomy, or parathyroidectomy by 4 surgeons between August 2015 November 2017. Eighty‐nine completed a phone survey about Prescription, demographic, comorbidity data were...
This study aimed to determine the feasibility of using probe-based confocal laser endomicroscopy (pCLE) in diagnostic differentiation non-neoplastic lesions from precancerous and cancerous head neck patients.Diagnostic test evaluation.Louisiana State University Health Shreveport.Intravenous injection fluorescein was given patients with (n = 21) followed by use a 1.8-mm GastroFlex probe oral cavity subsequent biopsies selected areas. Probe-based images were compared histologic evaluation...
The COVID-19 pandemic has resulted in a dramatic increase the number of patients requiring prolonged mechanical ventilation. Few studies have reported specific tracheotomy outcomes, and optimal timing patient selection criteria for remains undetermined. We delineate our outcomes tracheotomies performed on during peak at major epicenter United States.This is retrospective observational cohort study. Mortality, ventilation liberation rate, complication decannulation rate were...
The Corventis NUVANT™ Mobile Cardiac Telemetry system is an innovative solution in the field of continuous monitoring symptomatic and asymptomatic cardiac abnormalities to help physicians diagnose treat non-lethal arrhythmias. As FDA cleared product on market for more than 2 years, collected body patient data represents a unique powerful source clinical information. Analysis sample 951 NUVANT patients has revealed interesting statistics prevalence various arrhythmias population. population...
HPV(-) OCSCC resists radiation treatment. The CDKN2A gene, encoding p16INK4A, is commonly disrupted in OCSCC. p16 inhibits CDK4/CDK6, leading to cell cycle arrest, but the biological sequelae of CDK4/6 inhibition remains understudied. This study examines whether enhances response MTT assays were performed lines HN5 and CAL27 following treatment with palbociclib. Clonogenic survival synergy analyzed after (RT-2 or 4Gy), palbociclib (P) (0.5 µM 1 µM), concurrent combination (P+RT). DNA...
Although existing literature provides surgical recommendations for treating occult disease (cN0) in early-stage oral cavity squamous cell carcinoma (SCC), a focus on late-stage SCC is less pervasive.The medical records of 162 patients with pN0 who underwent primary neck dissections were reviewed. Lymph node yield as prognosticator was examined.Despite being staged pN0, that had higher lymph an improved regional/distant control rates, disease-free survival (DFS), disease-specific (DSS), and...