A5042969740- Head and Neck Cancer Studies
- Thyroid Cancer Diagnosis and Treatment
- Head and Neck Surgical Oncology
- Patient-Provider Communication in Healthcare
- Thyroid and Parathyroid Surgery
- Global Cancer Incidence and Screening
- Salivary Gland Tumors Diagnosis and Treatment
- Sinusitis and nasal conditions
- Economic and Financial Impacts of Cancer
- Radiation Dose and Imaging
- Head and Neck Anomalies
- Cancer Diagnosis and Treatment
- Esophageal Cancer Research and Treatment
- Ear and Head Tumors
- Healthcare cost, quality, practices
- Health Systems, Economic Evaluations, Quality of Life
- BRCA gene mutations in cancer
- Management of metastatic bone disease
- Colorectal and Anal Carcinomas
- Lung Cancer Treatments and Mutations
- Radiomics and Machine Learning in Medical Imaging
- Lung Cancer Research Studies
- Effects of Radiation Exposure
- Spinal Dysraphism and Malformations
- Biomedical Ethics and Regulation
Memorial Sloan Kettering Cancer Center
2016-2025
Ross University School of Veterinary Medicine
2025
Kettering University
2024
Vall d'Hebron Hospital Universitari
2021
Vall d'Hebron Institute of Oncology
2021
John Wiley & Sons (United States)
2016
Robert Wood Johnson Foundation
2014-2015
University of Pennsylvania
2014-2015
American Head & Neck Society
2015
New York University
2009-2014
Active surveillance of low-risk papillary thyroid cancer (PTC) is now an accepted alternative to immediate surgery, but experience with this approach outside Japan limited. The kinetics (probability, rate, and magnitude) PTC tumor growth under active have not been well defined.To describe the during surveillance.Cohort study 291 patients undergoing for (intrathyroidal tumors ≤1.5 cm) serial measurements via ultrasonography at a tertiary referral center in United States.Active...
<h3>Importance</h3> Recurrent and/or metastatic head and neck cancer is usually incurable. Implementation of precision oncology for these patients has been limited by incomplete understanding the molecular alterations underlying advanced disease. At same time, profiles many rare types are unknown. These significant gaps in knowledge need to be addressed rationally devise new therapies. <h3>Objective</h3> To illuminate distinct biology recurrent cancers review implementation with <h3>Design,...
Even though 15% to 50% of patients with head and neck squamous cell carcinoma (HNSCC) experience recurrence, relatively little is known regarding patterns treatment failure postrecurrence outcomes after chemoradiotherapy using modern radiation techniques (intensity-modulated radiotherapy [IMRT]). Recurrence are significantly affected by variations in the quality radiotherapy, which may confound findings from multicenter trials.To assess for HNSCC treated contemporary techniques.This large...
Objective Neck masses are common in adults, but often the underlying etiology is not easily identifiable. While infections cause most of neck children, persistent adults neoplasms. Malignant neoplasms far exceed any other adult mass. Importantly, an asymptomatic mass may be initial or only clinically apparent manifestation head and cancer, such as squamous cell carcinoma (HNSCC), lymphoma, thyroid, salivary gland cancer. Evidence suggests that a patient should considered malignant until...
BACKGROUND There has been increasing interest in the primary surgical treatment of patients with early T classification (T1‐T2) oropharyngeal squamous cell carcinoma (OPSCC), stated goal de‐escalating or avoiding adjuvant treatment. Herein, authors sought to determine degree which this translated into changes practice patterns, and rates adverse postoperative pathologic features. METHODS Patients T1 T2 OPSCC National Cancer Data Base who were treated from 2004 through 2013 categorized as...
Background: In 2016, encapsulated follicular variant of papillary thyroid carcinoma without invasion was renamed "noninvasive neoplasm with papillary-like nuclear features" (NIFTP) in order to reduce overtreatment this indolent tumor. However, many endocrinologists remain uneasy about managing large (≥4 cm) NIFTP conservatively radioactive iodine (RAI) therapy. The objectives study are characterize the clinicopathologic characteristics and outcome assist therapeutic decision making. Methods:...
The burden of concern for patients with thyroid cancer who undergo surgical intervention or without radioactive iodine is known to be substantial. For under active surveillance, this aspect the patient experience has not been described date and could a potential barrier broader acceptance surveillance as management strategy.To describe experiences in longest-standing largest program.This study used mixed method survey, semistructured interviews, field observation was conducted at Kuma...
Background: The change in size of the papillary thyroid cancer (PTC) nodule during active surveillance has traditionally been characterized as either stable, increasing, or decreasing based on changes maximal tumor diameter volume. More recently, it observed that observation are more complex with volume kinetic patterns can be stable (Pattern I), early increase II), later III), followed by stability IV), an V), a decrease VI). Methods: frequency, time course, and clinical correlates these...
In the neck, recipient vessels most frequently used for microsurgical reconstruction are compromised by prior surgery and radiation.We conducted a retrospective chart review of all patients who underwent microvascular between July 2001 June 2005. Donor vessels, vein grafts, flap survival were examined.Fourteen 197 (7%) identified with vessel-depleted neck. All had undergone neck dissection radiation (100%) or chemoradiation (42%). Free revascularization was achieved using transverse cervical...
Ideas and Opinions15 July 2014Faded Promises: The Challenge of Deadopting Low-Value CareBenjamin R. Roman, MD David A. Asch, MD, MBABenjamin MDFrom the Robert Wood Johnson Foundation Clinical Scholars Program Leonard Davis Institute Health Economics, University Pennsylvania, Center for Equity Research Promotion, Philadelphia Veterans Affairs Medical Center, Philadelphia, Head Neck Service, Memorial Sloan Kettering Cancer New York, York. MBAFrom York.Author, Article, Disclosure...
Transoral robotic surgery (TORS) has increased for treatment of oropharyngeal squamous cell carcinoma (OPSCC). To define the adoption TORS, we analyzed patterns surgical OPSCC in US.Cases T1-T3 treated with between 2010 and 2013 from National Cancer Database were queried.Of 3,071 patients who underwent primary management OPSCC, 846 (28%) TORS. On multivariable analysis, low tumor stage (T2 vs. T1: OR 0.75, CI 0.37-0.51, P < 0.0001; T3 O.R. 0.33, 0.28-0.38, 0.0001), at an academic cancer...
The recent overdiagnosis of subclinical, low-risk papillary thyroid cancer (PTC) coincides with a growing national interest in cost-effective health care practices. aim this study was to measure the relative cost-effectiveness disease surveillance PTC patients versus intermediate- and high-risk accordance American Thyroid Association risk categories.Two thousand nine hundred thirty-two who underwent thyroidectomy for differentiated between 2000 2010 were identified from institutional...
Background: Little is known about the role of emotions in treatment decisions for thyroid cancer. We aimed to characterize emotional content patient–surgeon communication during decision-making low-risk cancer treatment. Methods: audio-recorded conversations clinically or biopsy suspicious between patients (n = 30) and surgeons 9) two diverse, academic hospitals United States. Inductive deductive analyses were used verbatim transcripts. Results: Patients' expression emotion focused on...
Genomic profiling is now available for risk stratification of cytologically indeterminate thyroid nodules (ITNs). Mutations in
Objective: To determine whether intraoperative neural response telemetry (tNRT) is predictive of postoperative speech perception. Study Design: Retrospective review. Setting: Tertiary referral center. Patients: Children (n = 24) aged between 5 and 17 years adults 18 older 73) with severe-to-profound hearing loss implanted the Nucleus Freedom device 2005 2008 observed at least 1 year were included. Intervention: Intraoperative after insertion electrode array. Main Outcome Measure: Measures...
Abstract Background Esthesioneuroblastoma (ENB) is a rare neuroendocrine tumor. The purpose of this study was to compare the Kadish, tumor‐node‐metastasis (TNM), and Dulguerov's modified TNM staging in order determine impact stage on primary surgical treatment selection, margin status, survival. Methods National Cancer Database (NCDB) used identify patients diagnosed with ENB between 2004 2015. Patients were excluded based ability properly their disease as well availability data. Results...
Abstract Objective This study aims to characterize patient–surgeon discussions of voice‐related complications during thyroidectomy for low‐risk thyroid cancer. Study Design A qualitative study. Setting Three academic medical centers. Methods Pre‐operative clinic visits between 14 surgeons (6 otolaryngologists and 8 endocrine surgeons) 49 patients with (cT1‐2, N0) cancer were audio‐recorded transcribed. Qualitative analysis was used evaluate surgeon counseling strategies patient concerns...
Integrating behavioral and physiological assessment is critical to improve our ability assess animal welfare in biomedical settings. Hair, blood, saliva samples were collected from 40 recently acquired male African green monkeys (AGMs) analyze concentrations of hair cortisol, plasma β-endorphin, lysozyme alongside focal observations. The statistical methodology utilized machine learning multivariate generalized linear mixed models find associations between behaviors fluctuations lysozyme,...