Katie M White
A5071104569- Mental Health Research Topics
- Digital Mental Health Interventions
- Mobile Health and mHealth Applications
- Impact of Technology on Adolescents
- COVID-19 and Mental Health
- Sleep and related disorders
- Telemedicine and Telehealth Implementation
- Behavioral Health and Interventions
- Mental Health via Writing
- Child and Adolescent Psychosocial and Emotional Development
- Treatment of Major Depression
- Circadian rhythm and melatonin
- Functional Brain Connectivity Studies
- Health disparities and outcomes
- Health, Environment, Cognitive Aging
- Sleep and Wakefulness Research
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Rheumatoid Arthritis Research and Therapies
- Prenatal Substance Exposure Effects
- Healthcare Policy and Management
- Neuroscience of respiration and sleep
- Heart Rate Variability and Autonomic Control
- Mental Health Treatment and Access
- Tryptophan and brain disorders
- Child and Animal Learning Development
King's College London
1985-2025
Eunice Kennedy Shriver National Institute of Child Health and Human Development
2024
Research Network (United States)
2024
National Institutes of Health
2024
Guy's and St Thomas' NHS Foundation Trust
2022
Western Michigan University
2021
University of Ulster
2019
University of Oxford
2010
University of Exeter
1985
Abstract Background Major Depressive Disorder (MDD) is prevalent, often chronic, and requires ongoing monitoring of symptoms to track response treatment identify early indicators relapse. Remote Measurement Technologies (RMT) provide an opportunity transform the measurement management MDD, via data collected from inbuilt smartphone sensors wearable devices alongside app-based questionnaires tasks. A key question for field extent which participants can adhere research protocols completeness...
Research in mental health has implicated sleep pathologies with depression. However, the gold standard for assessment, polysomnography, is not suitable long-term, continuous, monitoring of daily sleep, and methods such as diaries rely on subjective recall, which qualitative inaccurate. Wearable devices, other hand, provide a low-cost convenient means to monitor home settings. The main aim this study was devise extract features, from data collected using wearable device, analyse their...
The mobility of an individual measured by phone-collected location data has been found to be associated with depression; however, the longitudinal relationships (the temporal direction relationships) between depressive symptom severity and phone-measured have yet fully explored.
Abstract Recent growth in digital technologies has enabled the recruitment and monitoring of large diverse populations remote health studies. However, generalizability inference drawn from remotely collected data could be severely impacted by uneven participant engagement attrition over course study. We report findings on long-term retention patterns a multinational observational study for depression containing active (surveys) passive sensor via Android smartphones, Fitbit devices 614...
Immersive virtual environments (IVEs) are potentially powerful educational resources but their application for children with Autism Spectrum Disorder (ASD) is under researched. This study aimed to answer two research questions: (1) Do ASD experience IVEs in different ways typically developing given cognitive, perceptual and sensory differences? (2) Can an IVE accurately simulate ecologically valid social situations? Ten 14 (TD) adolescents all aged 12—16 years experienced three IVEs. They...
Anxiety and depression are common, debilitating costly. These disorders influenced by multiple risk factors, from genes to psychological vulnerabilities environmental stressors, but research is hampered a lack of sufficiently large comprehensive studies. We recruiting 40,000 individuals with lifetime or anxiety broad assessment risks facilitate future research. The Genetic Links Depression (GLAD) Study (www.gladstudy.org.uk) recruits into the NIHR Mental Health BioResource. Participants...
Alterations in heart rate (HR) may provide new information about physiological signatures of depression severity. This 2-year study individuals with a history recurrent major depressive disorder (MDD) explored the intra-individual variations HR parameters and their relationship severity.Data from 510 participants (Number observations = 6666) were collected three centres Netherlands, Spain, UK, as part remote assessment disease relapse-MDD study. We analysed between severity, assessed every 2...
A number of challenges exist for the analysis mHealth data: maintaining participant engagement over extended time periods and therefore understanding what constitutes an acceptable threshold missing data; distinguishing between cross-sectional longitudinal relationships different features to determine their utility in tracking within-individual variation or screening individuals at high risk; heterogeneity with which depression manifests itself behavioral patterns quantified by passive...
Importance The function-based eat, sleep, console (ESC) care approach substantially reduces the proportion of infants who receive pharmacologic treatment for neonatal opioid withdrawal syndrome (NOWS). This reduction has led to concerns increased postnatal exposure in treatment. However, effect ESC on hospital outcomes pharmacologically treated NOWS is currently unknown. Objective To evaluate differences and total length stay (LOS) managed with vs usual Finnegan tool. Design, Setting,...
Prior research has associated spoken language use with depression, yet studies often involve small or non-clinical samples and face challenges in the manual transcription of speech. This paper aimed to automatically identify depression-related topics speech recordings collected from clinical samples. The data included 3919 English free-response via smartphones 265 participants a depression history. We transcribed automatic recognition (Whisper tool, OpenAI) identified principal...
Bleeding is the commonest and most concerning adverse event associated with anticoagulants. Bleeding, depending on severity, managed in various ways, for severe or life-threatening bleeding, specific antidotes are indicated recommended. This review provides guidance relating to direct oral anticoagulant (DOAC) reversal agents, antidotes. We discuss their indications use, dosing, potential side effects.
Speech contains neuromuscular, physiological and cognitive components, so is a potential biomarker of mental disorders. Previous studies indicate that speaking rate pausing are associated with major depressive disorder (MDD). However, results inconclusive as many small underpowered do not include clinical samples. These have also been unilingual use speech collected in controlled settings. If markers to help understand the onset progress MDD, we need uncover robust language establish...
Background Previous mobile health (mHealth) studies have revealed significant links between depression and circadian rhythm features measured via wearables. However, the comprehensive impact of seasonal variations was not fully considered in these studies, potentially biasing interpretations real-world settings. Objective This study aims to explore associations severity wearable-measured rhythms while accounting for impacts. Methods Data were sourced from a large longitudinal mHealth study,...
Major depressive disorder (MDD) is defined by an array of symptoms that make it challenging to understand the condition at a population level. Subtyping offers way unpick this phenotypic diversity for improved characterisation. We aimed identify depression subtypes longitudinally using Inventory Depressive Symptomatology: Self-Report (IDS-SR). A secondary analysis two-year cohort study called Remote Assessment Disease and Relapse in Disorder (RADAR-MDD), which collected data every three...
Abstract Background The outbreak of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which causes a clinical illness Covid-19, has had major impact on mental health globally. Those diagnosed with depressive disorder (MDD) may be negatively impacted by the global pandemic due to social isolation, feelings loneliness or lack access care. This study seeks assess 1st lockdown – pre-, during and post in adults recent history MDD across multiple centres. Methods is secondary analysis...
Background Gait is an essential manifestation of depression. However, the gait characteristics daily walking and their relationships with depression have yet to be fully explored. Objective The aim this study was explore associations between symptom severity daily-life derived from acceleration signals in real-world settings. Methods We used two ambulatory data sets (N=71 N=215) collected by wearable devices mobile phones, respectively. extracted 12 features describe distribution variance...
Abstract Background Cognitive symptoms are common during and following episodes of depression. Little is known about the persistence self-reported performance-based cognition with depression functional outcomes. Methods This a secondary analysis prospective naturalistic observational clinical cohort study individuals recurrent major depressive disorder (MDD; N = 623). Participants completed app-based cognitive function assessments alongside validated measures depression, disability,...
Background Remote measurement technology (RMT) involves the use of wearable devices and smartphone apps to measure health outcomes in everyday life. RMT with feedback form data visual representations can facilitate self-management chronic conditions, promote care engagement, present opportunities for intervention. Studies date focus broadly on multiple dimensions service users’ design preferences user experiences (eg, variables perceived importance quality medical advice provided) as opposed...
Importance Infants with neonatal opioid withdrawal syndrome (NOWS) cared for the Eat, Sleep, Console (ESC) care approach receive less pharmacologic treatment and have shorter hospital stays compared to usual Finnegan Neonatal Abstinence Scoring Tool, but effects of these approaches on feeding weight are unknown. Objective To evaluate practices trajectories in infants ESC vs care. Design, Setting, Participants ESC-NOW is a cluster randomized trial NOWS born at 36 weeks’ gestation or later 26...
Remote measurement technologies, such as smartphones and wearable devices, can improve treatment outcomes for depression through enhanced illness characterization monitoring. However, little is known about digital that are clinically meaningful to patients clinicians. Moreover, if these technologies be successfully implemented within treatment, stakeholders' views on the barriers facilitators of their implementation in must considered.This study aims identify targets health research explore...