A5058377143- Air Quality and Health Impacts
- Logic, Reasoning, and Knowledge
- Semantic Web and Ontologies
- Multi-Agent Systems and Negotiation
- Carcinogens and Genotoxicity Assessment
- Urban Transport and Accessibility
- Transportation Planning and Optimization
- Indoor Air Quality and Microbial Exposure
- Endometrial and Cervical Cancer Treatments
- Economic and Environmental Valuation
- Immunotoxicology and immune responses
- Synthesis and Characterization of Heterocyclic Compounds
- Simulation and Modeling Applications
- Climate Change and Health Impacts
- Metabolism and Genetic Disorders
- Toxic Organic Pollutants Impact
- Mesenchymal stem cell research
- Endoplasmic Reticulum Stress and Disease
- Advanced Measurement and Detection Methods
- Pesticide Exposure and Toxicity
- Cancer-related molecular mechanisms research
- Advanced Chemical Sensor Technologies
- Hydrocarbon exploration and reservoir analysis
- Innovative Educational Techniques
- Advanced optical system design
Shandong First Medical University
2017-2025
Harbin Institute of Technology
2024
China Design Group (China)
2023
Beijing Normal University
2020
System Simulation (United Kingdom)
2020
Air Force Institute of Aviation Medicine Affiliated Hospital
2019-2020
Xinjiang Academy of Agricultural Sciences
2020
University of Jinan
2020
Shandong Academy of Chinese Medicine
2013-2019
Academy of Medical Sciences
2017
Oxidative stress has been suggested to be one of the key drivers health impact particulate matter (PM). More studies on oxidative potential PM alone, but fewer have comprehensively evaluated effects external and internal exposure compositions in population. To investigate exposure–response relationship between its main with indicators. We conducted a cross-sectional study including 768 participants exposed particulates. Environmental levels fine (PM2.5), polycyclic aromatic hydrocarbons...
A study was conducted to determine the ability of demineralized bone matrix gel act as an osteoconductive/osteoinductive materiaI enhance cenine spinal fusion. Seven dogs underwent posterior fusion, Four-level fusions were performed with one four procedures at each level: decortication alone, added, autograft, or both gal and autograft. Dogs killed 6 weeks ano early histologic response studied. At untreated control sites, little formation evident. Gel-filled sitas showed abundant osteoid,...
This study assesses the effects of long-term exposure to ambient air pollutants on inflammatory response and lung function. We selected 390 male coke oven workers with polycyclic aromatic hydrocarbons (PAHs) fine particulate matter (PM2.5) 115 control workers. The average duration in exposed group was 9.10 years. total amount PAHs more enriched PM2.5 which collected from workshops compared areas. Correspondingly, internal indicated by urinary 1-hydroxypyrene (1-OHP) increased 25.7-fold that...
Gap junction intercellular communication (GJIC) between cardiomyocytes is essential for synchronous heart contraction and relies on connexin-containing channels. Connexin 43 (Cx43) a major component involved in GJIC tissue, its abnormal expression closely associated with various cardiac diseases. Silica nanoparticles (SNPs) are known to induce cardiovascular toxicity. However, the mechanisms through which plays role apoptosis induced by SNPs remain unknown. The aim of present study determine...
An analysis of 121 cases cervical spondylotic myelopathy treated by anterior excision the disc and fusion was undertaken. All patients were followed at least six months, follow-up averaged 22 months. Results showed that 97.5% had no aggravation symptoms, 90.9% improved, 72.6% able to resume normal activity. Surgical intervention can greatly improve prospects with severe myelopathy, its use should not be lightly ruled out. Autografts yield higher rates better overall results than homografts....
We sought to clarify the association of occupational formaldehyde exposure with DNA strand breaks, chromosome damage and DNA-protein crosslinks (DPCs) in peripheral blood (PB) lymphocytes plywood workers.We determined Olive tail moment (OTM) values, micronucleus (MN) frequencies DPC rates PB 178 workers divided into control lower higher groups according their current levels examined each end point number work years. also an additional 62 before after 8-hour for validating association.OTM...
Formaldehyde (FA) is a well-known irritant, and it suggested to increase the risk of immune diseases cancer. The present study aimed evaluate distribution major lymphocyte subsets cytokine expression profiles in peripheral blood FA-exposed workers. A total 118 workers 79 controls were enrolled study. High performance liquid chromatography, flow cytometry, cytometric bead array used analyze FA air sample formic acid urine, subpopulations, serum cytokines, respectively. divided into low high...
Crotonaldehyde is a ubiquitous hazardous pollutant, present in cigarette smoke and automobile exhaust endogenously generated by lipid peroxidation. Most of the current studies focus on its lung toxicity. However, there have been few investigations cardiac renal toxicity caused crotonaldehyde exposure. We hypothesized that oral intake can cause inflammatory oxidative/nitrosative damage to heart kidneys. Therefore, we treated male rats with gavage at 0, 2.5, 4.5, 8.5 mg/kg/day for 120 d...
Enhancing the bus share rate is a major measure to relieve traffic congestion. To analyze effect of public transit policy, this paper establishes MNL models based on both SP data and combining RP data, which was collected in Jinan city. Then analyzes how influencing factors affect choice proportion travel mode for user groups. In end, obtains some significant conclusions proposes measures would enhance attraction.
In the process of oil and natural gas exploration development, density logging curves play a crucial role, providing essential evidence for identifying lithology, calculating reservoir parameters, analyzing fluid properties. Due to factors such as instrument failure wellbore enlargement, data some well segments may become distorted or missing during actual process. To address this issue, paper proposes curve reconstruction model that integrates multi-head self-attention mechanism (MSA) with...
ABSTRACT Ovarian cancer is one of the leading gynecologic malignancies globally, 5‐year survival rate for patients with advanced stage ovarian very low. Our objective was to test hypothesis that miR‐335 associated cancer. Bioinformatics tools and luciferase report assay were used select target miR‐335, real‐time PCR detect expression ERBB4 in different genotype groups. Finally, Cox regression Kaplan‐Meier analyses assess relationship ovary Firstly, individuals carried rs186724 GG had poorer...
Abstract Crotonaldehyde, a highly toxic α, β‐unsaturated aldehyde, is ubiquitous hazardous pollutant. Because of its extreme toxicity and ubiquity in all types smoke, most current research focuses on the lung such air pollutants. However, specific mechanism pulmonary caused by crotonaldehyde remains unclear, especially after long‐term exposure to at low dose. Therefore, aim present study determine whether crotonaldehyde‐induced oxidative damage inflammation promote apoptosis rats via...
This paper establishes MNL and joint SP-RP models to analyze the bus choice behavior of car owners based on disaggregate utility theory in middle-sized cities China. The preference survey travel for traveler groups is conducted Ji'nan city. Travel time, comfort, parking fee fuel cost are chosen as four important factors intent who will switch public transit. research finds that more sensitive change not comfort. sensitivity time decreases increases. conclusions provide base decision – making...
Crotonaldehyde is a highly toxic pollutant, widely present in tobacco smoke and automobile exhaust. Exposure to crotonaldehyde can cause hepatotoxicity induce liver tumors rats; however, the underlying mechanism unclear. Liver cells contain many mitochondria, which serve maintain energy levels body. We hypothesized that metabolism disorder caused by mitochondrial dysfunction an important of injury rats exposed crotonaldehyde. To test this, we randomly divided 40 male Wistar into four groups,...
Crotonaldehyde is a hazardous pollutant present in cigarette smoke and automobile exhausts that generated by lipid peroxidation, harmful to reproductive organs. Although we are often exposed low doses of crotonaldehyde daily, its adverse effects on the organs have not been fully elucidated. To elucidate them, administered (0, 2.5, 4.5, 8.5 mg/kg) gavage for 150 days male Wister rats, evaluated effect their testicular tissues. Body weight, testis coefficient, sperm count, motility decreased....
Objective: To investigate the effect of subchronic exposure to crotonaldehyde on reproductive damage and oxidative stress in male rate. Methods: Forty SPF Wistar rats were randomly divided into four group: a control group 3 groups, 10 per group. The each continuously administrated with (normal saline) for 1 time/d. For 128 d, doses 0.0, 2.5, 4.5, 8.5 mg/kg. After end exposure, body weight, weight testis epididymis was measured, calculating organ coefficient. left spermatozoon tail used...