A5047040442- Palliative Care and End-of-Life Issues
- Family and Patient Care in Intensive Care Units
- Patient Dignity and Privacy
- Childhood Cancer Survivors' Quality of Life
- Ethics in medical practice
- Intensive Care Unit Cognitive Disorders
- Antimicrobial Resistance in Staphylococcus
- Healthcare Decision-Making and Restraints
- Cardiac Arrest and Resuscitation
- Cardiac Structural Anomalies and Repair
- Infective Endocarditis Diagnosis and Management
- Growth Hormone and Insulin-like Growth Factors
- Patient-Provider Communication in Healthcare
- Grief, Bereavement, and Mental Health
- Cardiac pacing and defibrillation studies
- Streptococcal Infections and Treatments
- Cancer survivorship and care
- Bacterial Identification and Susceptibility Testing
- Mechanical Circulatory Support Devices
- Cardiac Valve Diseases and Treatments
- Pain Management and Opioid Use
- Muscle Physiology and Disorders
- Cardiac Arrhythmias and Treatments
- Religion, Spirituality, and Psychology
- Urological Disorders and Treatments
Düsseldorf University Hospital
2017-2024
Heinrich Heine University Düsseldorf
2017-2024
Centrum für Integrierte Onkologie
2019-2024
University of Southern California
2018-2019
University of Florida Health
2019
Los Angeles Medical Center
2018
Kaiser Permanente
2018
Pacific University Oregon
2016-2017
Hôpital Louis Pradel
2017
Loewenstein Hospital Rehabilitation Center
1985-1990
Abstract Background Patients in palliative care need rapid-acting pharmacological options for psychological distress. N-methyl-D-aspartate antagonist ketamine is known to have a fast onset of anti-depressant and anxiolytic action. Its S -enantiomer S- (or esketamine) an analgesic used as routine treatment refractory pain intravenous infusion (0.25 mg/kg over 45 min). This study investigates whether therapy has positive impact on distress caused by anxiety depression care. Methods Patient...
The desire to die can occur in palliative care patients with a prevalence of up 22%. Not every is accompanied by pressure act, but usually burden that arise from various factors. To address this appropriately, health workers should be trained. Based on an evaluated course handling the die, elective for medical students was developed and evaluated. In order identify impact course's content, comparison attitudes towards assisted dying two other participant groups conducted. Therefore, three...
Clinical predictions alone are insufficiently accurate to identify patients with specific types of bloodstream infection; laboratory assays might improve such predictions. Therefore, we performed a prospective cohort study 356 episodes sepsis syndrome and did Limulus amebocyte lysate (LAL) for endotoxin. The main outcome measures were bacteremia infection due gram-negative organisms; other secondary outcomes. Assays defined as positive if the result was > or = 0.4 enzyme-linked immunosorbent...
Abstract Background In the SARS-CoV-2 pandemic, general and specialist Palliative Care (PC) plays an essential role in health care, contributing to symptom control, psycho-social support, providing support complex decision making. Numbers of COVID-19 related deaths have recently increased demanding more palliative care input. Also, pandemic impacts on for non-COVID-19 patients. Strategies seriously ill dying people times are lacking. Therefore, program ‘Palliative Pandemics’ (PallPan) aims...
ABSTRACT Staphylococcus aureus bacteremia (SAB) causes high rates of morbidity and death. Several studies in academic health settings have demonstrated that consultations from infectious diseases specialists improve the quality care clinical outcomes for SAB. Few data describe impact resource-limited such as community hospitals are available. This retrospective cohort study evaluated adherence to quality-of-care indicators SAB a five-hospital system (range 95 272 available beds per...
As part of an elective course, the Interdisciplinary Centre for Palliative Medicine at Duesseldorf University Hospital offers medical students opportunity to personally meet and talk a seriously ill patient on one or more occasions. The future physicians are provided with broaden their professional competence, i.e. knowledge skills in patient-centred communication end life, enhance personal example how professionally handle own emotions. A topical e-learning module helps prepare meetings,...
Abstract Purpose Triggers have been developed internationally to identify intensive care patients with palliative needs. Due their work, nurses are close the patient and perspective should therefore be included. In this study, potential triggers were first identified then a questionnaire was analyse acceptance among German nurses. Methods For qualitative part of mixed methods focus groups conducted from different disciplines (surgery, neurosurgery, internal medicine), which selected by...
The SARS-CoV-2 pandemic has presented major challenges to the health system. Despite high acute case numbers, patients without Covid-19 still need be cared for. Due severity of disease and a possible stressful overall situation, with palliative care needs also require comprehensive during times. In addition specialized facilities, this takes place in non wards. order ensure general times, experience staff should used. aim paper is examine solutions for inpatients relation seriously ill dying...
Abstract Background Palliative care teams work under challenging conditions in a sensitive setting with difficult tasks. The multi-professional team can play an important role. Mindfulness and compassion-based practices are used to build resilience. Our aim was examine (1) feasibility acceptability, (2) satisfaction impact, (3) opportunities limitations of mindfulness course. Methods An eight-week compassion course delivered university-based specialized palliative unit. A meditation teacher...
Ceftaroline is often used in durations greater than that studied clinical trials. Several retrospective, non-comparative studies have suggested a higher anticipated incidence of neutropenia patients receiving prolonged treatment with ceftaroline. We sought to determine if ceftaroline was associated by comparing the several comparative antibiotics.Patients 14 or more consecutive days were compared cefazolin, daptomycin, linezolid, nafcillin vancomycin (control group). The primary outcome...
Repeat hospitalizations, complications, and psychosocial burdens are common in patients with left ventricular assist devices (LVAD). Specialist palliative care (sPC) involvement supports during decision-making until end-of-life. In the United States, guidelines recommend early specialist (esPC) prior to implantation. Yet, data about sPC esPC Europe scarce.This is a retrospective descriptive study of deceased LVAD who had received their LVAD-related admissions two university hospitals...
COVID-19 patients who may require invasive therapeutic procedures such as extracorporeal membrane oxygenation (ECMO) have high symptom burden and in-hospital mortality. In addition, awake on ECMO are new in the intensive care unit (ICU) setting. Inpatient specialist palliative (sPC) provides support control a physical, psychosocial spiritual level. The field of sPC is still important to investigate. We aim analyze ICU with regard patient characteristics symptoms from perspective. conducted...
Immune checkpoint inhibitors (ICI) have emerged as a successful treatment option for diverse cancer entities. However, ICI therapy can be associated with immune-related adverse events (irAE) that affect any organ system. These side effects severe, irreversible and sometimes even fatal. Due to the presentation often unspecific clinical patterns, end-of-life care concepts may pursued hastily suspecting disease progression in oncological patients receiving palliative (PC).This report describes...
According to § 27 and 87 1b of the German Social Code, Book V, general outpatient palliative care (GOPC) aims promote, maintain, improve quality life self-determination seriously ill people. It should enable them live in dignity until death their preferred environment. Instead a curative approach GOPC treatment focuses on multiprofessional objective alleviating symptoms suffering case-by-case basis using medication or other measures, as well management an individual plan. The aim this study...
Health-care professionals are confronted with patients who wish to end their lives through voluntarily stopping eating and drinking (VSED). During VSED, symptoms such as agitation, thirst or psychological distress may arise, thus making close medical accompaniment necessary. Dealing these can put a high burden on palliative care teams. Furthermore, divergent perceptions of the ethical classification VSED lead moral distress. The aim this study was assess influence experience gained over time...
14630 Background: VEGFR-1 is expressed on both tumor vasculature and a wide range of human tumors. IMC-18F1 recombinant monoclonal IgG1 antibody that directly targets so as to block ligand binding and, in turn, downstream signaling. activation also critical for epithelial-mesenchymal transformation mediator circulating hematopoietic progenitor cells condition the microenvironment enabling growth metastases. Methods: This Phase 1 study IMC- 18F1 was designed evaluate safety, pharmacokinetics...
Chez le chien anesthésié, en étudiant les variations de la sécrétion rénine dans des conditions précises, nous avons tenté dissocier facteurs jouant sur cellules juxtaglomérulaires ceux agissant macula densa. L'activité-rénine sang veineux rénal, débit sanguin pression artérielle moyenne rénale ont été mesurés simultanément. Voici nos résultats: (a) Dans zone d'autorégulation du est inversement proportionelle à moyenne; mais cette baisse pour une perfusion inférieure 50 mm Hg. (b)...