A5027878704- Blood Pressure and Hypertension Studies
- Health Systems, Economic Evaluations, Quality of Life
- Meta-analysis and systematic reviews
- Atrial Fibrillation Management and Outcomes
- Healthcare cost, quality, practices
- Pharmaceutical Economics and Policy
- Venous Thromboembolism Diagnosis and Management
- Pharmaceutical industry and healthcare
- Innovations in Medical Education
- Respiratory and Cough-Related Research
- Health Sciences Research and Education
- Influenza Virus Research Studies
- Heart Rate Variability and Autonomic Control
- SARS-CoV-2 detection and testing
- SARS-CoV-2 and COVID-19 Research
- Clinical practice guidelines implementation
- Primary Care and Health Outcomes
- Pneumonia and Respiratory Infections
- Respiratory viral infections research
- Clinical Reasoning and Diagnostic Skills
- Autopsy Techniques and Outcomes
- Health and Medical Research Impacts
- Pharmaceutical studies and practices
- COVID-19 epidemiological studies
- Opioid Use Disorder Treatment
University of Oxford
2015-2024
Nuffield Health
2016-2023
Kellogg's (Canada)
2021
Centre for Sustainable Healthcare
2021
Primary Health Care
2007-2020
Presbyterian Hospital
2020
Cornell University
2020
Brown University
2020
Island Institute
2020
University of British Columbia
2019
Replicating non-pharmacological treatments in practice depends on how well they have been described research studies
<h2>Summary</h2><h3>Background</h3> Studies evaluating titration of antihypertensive medication using self-monitoring give contradictory findings and the precise place telemonitoring over alone is unclear. The TASMINH4 trial aimed to assess efficacy self-monitored blood pressure, with or without telemonitoring, for in primary care, compared usual care. <h3>Methods</h3> This study was a parallel randomised controlled done 142 general practices UK, included hypertensive patients older than 35...
Clinical research should ultimately improve patient care. For this to be possible, trials must evaluate outcomes that genuinely reflect real-world settings and concerns. However, many continue measure report fall short of clear requirement. We highlight problems with trial make evidence difficult or impossible interpret undermine the translation into practice policy. These complex issues include use surrogate, composite subjective endpoints; a failure take account patients’ perspectives when...
IDEAL is a framework for evaluations of surgical innovations, which follow distinct development pathway differing from the approach developed pharmacological interventions. Many and evaluation challenges are shared by other interventional therapies, requiring individual therapist skills customisation treatment to individual, partly through medical devices. This paper provides an overview recommendations, focuses on first two stages: idea development.
Discrepancies between pre-specified and reported outcomes are an important source of bias in trials. Despite legislation, guidelines public commitments on correct reporting from journals, outcome misreporting continues to be prevalent. We aimed document the extent misreporting, establish whether it was possible publish correction letters all misreported trials as they were published, monitor responses editors trialists understand why persists despite address it.We identified five high-impact...