Marloes Franssen
A5082710288- Blood Pressure and Hypertension Studies
- Parkinson's Disease Mechanisms and Treatments
- Pregnancy and preeclampsia studies
- Cerebral Palsy and Movement Disorders
- Restless Legs Syndrome Research
- Cardiac, Anesthesia and Surgical Outcomes
- Urinary Tract Infections Management
- Balance, Gait, and Falls Prevention
- Heart Rate Variability and Autonomic Control
- Maternal and fetal healthcare
- Cardiac Health and Mental Health
- Birth, Development, and Health
- Bladder and Urothelial Cancer Treatments
- Bone fractures and treatments
- Cardiovascular and exercise physiology
- Voice and Speech Disorders
- Maternal and Neonatal Healthcare
- Mobile Health and mHealth Applications
- Cardiovascular Syncope and Autonomic Disorders
- Gait Recognition and Analysis
- Lower Extremity Biomechanics and Pathologies
- Neurological disorders and treatments
- Botulinum Toxin and Related Neurological Disorders
- Climate Change and Health Impacts
- Cardiovascular Health and Disease Prevention
University of Oxford
2016-2024
Nuffield Orthopaedic Centre
2021-2024
Oxford Brookes University
2014-2024
St Thomas' Hospital
2022
King's College London
2022
University of Southampton
2022
The Stables
2022
University of Birmingham
2022
Institute for Healthcare Improvement
2022
University of Cambridge
2022
<h2>Summary</h2><h3>Background</h3> Studies evaluating titration of antihypertensive medication using self-monitoring give contradictory findings and the precise place telemonitoring over alone is unclear. The TASMINH4 trial aimed to assess efficacy self-monitored blood pressure, with or without telemonitoring, for in primary care, compared usual care. <h3>Methods</h3> This study was a parallel randomised controlled done 142 general practices UK, included hypertensive patients older than 35...
The use of self-monitoring blood pressure, with or without telemonitoring, to guide therapy decisions by physicians for patients hypertension has been recently demonstrated reduce pressure compared using clinic monitoring (usual care). However, both the cost-effectiveness these strategies usual care, and whether additional benefit telemonitoring alone could be considered value money, are unknown. This study assessed physician titration antihypertensive medication self-monitored make...
<h3>Importance</h3> Inadequate management of elevated blood pressure (BP) is a significant contributing factor to maternal deaths. Self-monitoring BP in the general population has been shown improve diagnosis and hypertension; however, little known about its use pregnancy. <h3>Objective</h3> To determine whether self-monitoring higher-risk pregnancies leads earlier detection pregnancy hypertension. <h3>Design, Setting, Participants</h3> Unblinded, randomized clinical trial that included 2441...
Inadequate management of elevated blood pressure is a significant contributing factor to maternal deaths. The role self-monitoring in pregnancy improving clinical outcomes for the pregnant individual and infant unclear.To evaluate effect self-monitoring, compared with usual care alone, on control other related outcomes, individuals hypertension.Unblinded, randomized trial that recruited between November 2018 September 2019 15 hospital maternity units England. Individuals chronic hypertension...
Introduction Self-monitoring of blood pressure (BP) in pregnancy could improve the detection and management hypertension, while also empowering engaging women their own care. Two linked trials aim to evaluate whether BP self-monitoring improves raised during higher risk pregnancies (BUMP 1) reduces systolic hypertensive 2). Methods analyses Both are multicentre, non-masked, parallel group, randomised controlled trials. Participants will be with telemonitoring or usual BUMP 1 recruit a...
<h3>Background</h3> Evidence for longer term exercise delivery people with Parkinson9s disease (PwP) is deficient. <h3>Aim</h3> Evaluate safety and adherence to a minimally supported community intervention estimate effect sizes (ES). <h3>Methods</h3> 2-arm parallel phase II randomised controlled trial blind assessment. PwP able walk ≥100 m no contraindication were recruited from the Thames valley, UK, (1:1) (exercise) or control (handwriting) groups, via concealed computer-generated list....
Background Self-monitoring of blood pressure is common but how telemonitoring with a mobile healthcare (mHealth) solution in the management hypertension can be implemented by patients and professionals (HCPs) currently unclear. Aim Evaluation facilitators barriers to self- interventions for within Telemonitoring Hypertension (TASMINH4) trial. Design setting An embedded process evaluation TASMINH4 randomised controlled trial (RCT), West Midlands, UK primary care, conducted between March 2015...
Symptoms of Parkinson's can result in low physical activity and poor sleep patterns which have a detrimental effect on person's quality life. To date, studies looking into exercise interventions for people with (PwP) symptom management are promising but inconclusive. The aim this study is to estimate the clearly defined prescription general levels, fatigue, sleep, life PwP. Method. PwP randomised either an group (29; 16 males, 13 females; mean age 67 years (7.12)) or control handwriting (36;...
Objectives To investigate the acute and adaptation cardiovascular metabolic training responses in people with Parkinson’s disease (pwP). Design (1) A cross-sectional study of exercise response pwP compared sedentary controls (2) an interventional pwP. Setting Community leisure facilities. Participants (n=83) (n=55). Interventions Study 1 included participants from a two-arm-parallel single-blind phase II randomised controlled trial (RCT), that undertook baseline maximal incremental test 2...
Self-monitoring of hypertension is associated with lower systolic blood pressure (SBP). However, evidence for the use self-monitoring to titrate antihypertensive medication by physicians equivocal. Furthermore, there some efficacy telemonitoring in management but it not clear what this adds over and above self-monitoring. This trial aims evaluate whether GP led titration using results SBP compared usual care anything alone. will be a pragmatic primary based, unblinded, randomised controlled...
Objective:To report on the control group of a trial primarily designed to investigate exercise for improving mobility in people with Parkinson's disease (pwP). The undertook handwriting intervention attention and time spent practising specific activity. Design:Secondary analysis two-arm parallel phase II randomized controlled blind assessment. Participants:PwP able walk ⩾100 m no contraindication were recruited from Thames Valley, UK, (1:1) or handwriting, via concealed computer-generated...
Introduction Recurrent urinary tract infections (RUTIs) have a significant negative impact on quality of life and healthcare costs. To date, daily prophylactic antibiotics are the only treatment which been shown to help prevent RUTIs. D-mannose is type sugar believed inhibit bacterial adherence uroepithelial cells, already being used by some women in an attempt There currently insufficient rigorous evidence base decisions about its use. The recurrent (MERIT) study will evaluate whether...
Abstract Background Hypertensive disorders in pregnancy, particularly pre-eclampsia, pose a substantial health risk for both maternal and foetal outcomes. The BUMP (Blood Pressure Self-Monitoring Pregnancy) interventions are being tested trial. They aim to facilitate the early detection of raised blood pressure through self-monitoring. This article outlines how self-monitoring trial were developed modified using person-based approach promote engagement adherence. Methods Key behavioural...
Aims Fractures of the humeral shaft represent 3% to 5% all fractures. The most common treatment for isolated diaphysis fractures in UK is non-operative using functional bracing, which carries a low risk complications, but associated with longer healing time and greater nonunion than surgery. There an increasing trend surgical treatment, may lead quicker recovery lower rates fracture bracing. However, surgery inherent risk, including infection, bleeding, nerve damage. aim this trial evaluate...
ABSTRACT (Abstracted from JAMA 2022;327:1656–1665 It is estimated that approximately 10% of pregnancies worldwide in 2019 were affected by elevated blood pressure (BP). The United Kingdom has previously reported inadequate monitoring BP as a significant contributing factor to maternal death.
People with Parkinson's disease (PwPD) present motor alterations which can impact daily life tasks that require speed and/or accuracy of movement.
Objective: Previous studies evaluating titration of antihypertensive medication using self-monitoring have contradictory findings and the precise place telemonitoring over alone is unclear. The TASMINH4 trial aimed to assess efficacy self-monitored blood pressure, with or without telemonitoring, for in primary care, compared usual care. Design method: Randomised controlled 142 UK General Practices including hypertensive patients, aged 35, pressure >140/90mmHg who were willing self-monitor...
Abstract Background Patellar dislocations mainly affect adolescents and young adults. After this injury, patients are usually referred to physiotherapy for exercise-based rehabilitation. Currently, limited high-quality evidence exists guide rehabilitation practice treatment outcomes vary. A full-scale trial comparing different approaches would provide inform practice. Whether is feasible uncertain: the only previous that compared programmes in patient population had high loss follow-up. This...