A5064724687- Bladder and Urothelial Cancer Treatments
- Prostate Cancer Diagnosis and Treatment
- Prostate Cancer Treatment and Research
- Urinary and Genital Oncology Studies
- Urological Disorders and Treatments
- Urinary Bladder and Prostate Research
- Renal cell carcinoma treatment
- Renal and Vascular Pathologies
- Urologic and reproductive health conditions
- Renal Transplantation Outcomes and Treatments
- Frailty in Older Adults
- Cancer Immunotherapy and Biomarkers
- Ureteral procedures and complications
- Dietetics, Nutrition, and Education
- MRI in cancer diagnosis
- Migraine and Headache Studies
- Organ Transplantation Techniques and Outcomes
- Trauma and Emergency Care Studies
- Cancer survivorship and care
- Cancer, Stress, Anesthesia, and Immune Response
- Multiple Myeloma Research and Treatments
- Nausea and vomiting management
- COVID-19 and healthcare impacts
- Case Reports on Hematomas
- Peptidase Inhibition and Analysis
Kagawa University
2019-2025
Kurashiki Central Hospital
2020-2025
Health Care Foundation
2020
Mizushima Central Hospital
2017
Objectives To examine prostate cancer staging in real‐world clinical practice. Methods We retrospectively analyzed 698 patients referred to the Department of Urology at Kagawa University Hospital from 25 facilities for treatment June 2014 December 2023. Patients treated with dutasteride ( n = 10) and who underwent our institution 197) were excluded. The outcomes interest proportion computed tomography bone scintigraphy, diagnostic rates metastasis stratified by D'Amico risk, incidental...
Abstract Objective To evaluate the real-world clinical usage and effectiveness of apalutamide in men with nonmetastatic castration-resistant prostate cancer (nmCRPC). Methods We retrospectively reviewed data 186 who received across 17 institutions. The primary outcomes were for nmCRPC: prior other androgen receptor signaling inhibitors (ARSIs), radical treatment, distribution prostate-specific antigen (PSA) doubling time (PSA-DT) at initial administration apalutamide. secondary efficacy...
Objective To examine the association between substaging and outcomes following radical cystectomy (RC) in patients with stage III bladder cancer. Methods We conducted a retrospective observational study using nationwide data from Japan, including 708 cancer who underwent RC. Substaging was based on American Joint Committee Cancer's 8th edition. pT3‐4aN0 pTanyN1 were newly defined as IIIA, while pTanyN2‐3 IIIB. Baseline covariates balanced inverse probability of treatment weighting. analyzed...
Background/Objectives: The objective of this study was to evaluate the oncological outcomes and safety nerve-sparing (NS) robot-assisted radical prostatectomy (RARP) when applied without Prostate Imaging-Reporting Data System (PI-RADS) ≥3 lesions or Gleason pattern ≥4 on biopsy in peripheral zone (PZ). Methods: We retrospectively analyzed 208 patients who underwent RARP between August 2017 December 2022, excluding those had received preoperative hormonal therapy. After NS status...
To analyse the impact of histological discordance subtypes (subtypes or divergent differentiation [DD]) in specimens from transurethral resection (TUR) and radical cystectomy (RC) on outcome patients with bladder cancer receiving RC.
Immune checkpoint inhibitors are new immunotherapy drugs globally used for many malignancies, including renal cell carcinoma. Myocarditis as an immune-related adverse event is rare but highly fatal, suggesting that its frequency may be higher than reported. This paper describes a case of myocarditis developed asymptomatically following ipilimumab and nivolumab combination therapy A 71-year-old Asian man who presented to hospital with fever, fatigue, weight loss approximately 10 kg within 2...
Abstract Background Chronic inflammation is thought to be a major causative factor for the development of benign prostatic hyperplasia (BPH) and lower urinary tract symptoms (LUTS). Tadalafil, phosphodiesterase type 5 inhibitor (PDE5-I), which has been used treatment BPH-LUTS in daily practice, known act at several organs. In this study, focused on prostate, we examined effect tadalafil pathological changes inflammatory factors rat nonbacterial prostatitis (NBP) model. Methods Forty...
To assess whether the coronavirus disease (COVID-19) pandemic affected outcomes of robot-assisted radical prostatectomy (RARP) and urologists' treatment behaviors.
This study conducted a national questionnaire survey of Japanese urologists from treatment perspective for older patients with prostate cancer.A was distributed to 922 teaching hospitals the Urological Association. Questionnaire items included years urologist experience, gender, workplace, equipment owned, daily specialty practice area, urological cancer specialty, reference adults, upper age limit radical treatment, medication, and two hypothetical cases Gleason grade group 2 or without...
Abstract Background Japanese men receiving apalutamide often experience skin-adverse events (AEs), possibly requiring treatment interruption or dose reduction. However, concerns have arisen regarding the impact of these adjustments on efficacy apalutamide. Our study evaluated efficacy, safety, and persistence in with metastatic castration-sensitive prostate cancer (mCSPC). Methods We retrospectively reviewed medical records 108 mCSPC from 14 institutions. The primary outcomes were...
Objective To conduct a national questionnaire survey of Japanese urologists on active surveillance (AS) for low‐ and intermediate‐risk prostate cancer (PCa). Methods A was sent to 922 Urological Association Teaching Base Hospitals. The items included were years experience as urologist, sex, workplace, treatment equipment owned, specialty area daily practice, urological cancer, six hypothetical cases AS. categorized by the following Gleason scores: 3 + low risk PCa, 4 intermediate risk, with...
In men undergoing upfront active surveillance, predictors of adverse pathology in radical prostatectomy specimens, including intraductal carcinoma the prostate and cribriform patterns, remain unknown. Therefore, we aimed to examine whether specimens could be predicted using preoperative patient characteristics.We re-reviewed available from 1035 prospectively enrolled PRIAS-JAPAN cohort between January 2010 September 2020. We defined on as Gleason grade group ≥3, pT stage pN positivity or...
592 Background: We aimed to evaluate the effect of number neoadjuvant chemotherapy (NAC) cycles and adding adjuvant (AC) after NAC in muscle-invasive bladder cancer (MIBC) on overall survival (OS). Methods: This multicenter retrospective study included 2674 patients with MIBC who underwent radical cystectomy (RC) from 36 institutions within Japanese Urological Oncology Group. Among them, we selected 1687 cT2-4NxM0 were treated RC alone or plus perioperative chemotherapy. compared (2 vs. ≥3...
Abstract Objective To investigate the prevalence of frailty and its effects on cancer-related fatigue quality life among patients with prostate cancer. Methods In this cross-sectional study, questionnaires were administered to 254 outpatients who visited Department Urology at Kagawa University Hospital for cancer; finally, 108 analyzed. Frailty, assessed using G8 screening tool, Japanese version Brief Fatigue Inventory Short Form 8 Health Survey, respectively. We defined based a score ≤14...
To determine the effects of prophylactic urethrectomy (PU) on oncological and perioperative outcomes in patients with bladder cancer (BC) undergoing radical cystectomy (RC).
Objectives This study aims to develop a prognostic model that estimates the post‐operative risk of cancer‐specific mortality in patients with bladder cancer who underwent radical cystectomy (RC). Methods We analyzed data from had undergone without receiving adjuvant chemotherapy across 36 institutions Japan Urological Oncology Group. The were randomly split into training ( N = 1348) and validation sets 674) 2:1 ratio. Twenty‐five variables analyzed, multivariable Cox regression predicting...
There have been reports of surgery for residual ureteral tumors, most them involved open surgeries. Herein, we report a case retroperitoneal scopic left resection and partial cystectomy, performed by placing fluorescent catheter in the ureter.
New-onset diabetes after kidney transplantation (NODAT) adversely affects patient survival. Excessive fat accumulation is generally considered a risk factor of NODAT. Body mass index (BMI) and abdominal circumference (AC) are frequently used to assess but cannot directly measure it. This study measured body area (BFA) via computed tomography aimed clarify whether preoperative BFA can predict the development NODAT more accurately than BMI AC.This retrospective included 62 patients without...