A5103057947- Esophageal and GI Pathology
- Esophageal Cancer Research and Treatment
- Gastric Cancer Management and Outcomes
- Gastroesophageal reflux and treatments
- Lung Cancer Diagnosis and Treatment
- Gastrointestinal disorders and treatments
- Diverticular Disease and Complications
- Bariatric Surgery and Outcomes
- Gastrointestinal Tumor Research and Treatment
- Helicobacter pylori-related gastroenterology studies
- Cardiac, Anesthesia and Surgical Outcomes
- Dysphagia Assessment and Management
- Anorectal Disease Treatments and Outcomes
- Ureteral procedures and complications
- Intraperitoneal and Appendiceal Malignancies
- Amoebic Infections and Treatments
- Appendicitis Diagnosis and Management
- Eosinophilic Esophagitis
- Congenital Diaphragmatic Hernia Studies
- Infectious Diseases and Tuberculosis
- Neuroendocrine Tumor Research Advances
- Tumors and Oncological Cases
- Cancer Mechanisms and Therapy
- Omental and Epiploic Conditions
- Dermatological and COVID-19 studies
IRCCS Policlinico San Donato
2016-2025
University of Milan
2012-2025
Universität Innsbruck
2025
Innsbruck Medical University
2025
Radboud University Medical Center
2022
Radboud University Nijmegen
2022
Centro di Riferimento Oncologico
1995-2003
BACKGROUNDMediastinal leakage (ML) is one of the most feared complications esophagectomy.A standard strategy for its diagnosis and treatment has been
Abstract The magnetic sphincter augmentation (MSA) device has been proven safe and effective in controlling typical reflux symptoms esophageal acid exposure for up to 6-year follow-up. Longer term outcomes have not reported yet. A prospectively maintained database was reviewed assess long-term safety efficacy of the laparoscopic MSA procedure at a single referral center. Gastro-Esophageal Reflux Disease-Health Related Quality Life (GERD-HRQL), use proton-pump inhibitors (PPI), were compared...
High-resolution manometry (HRM) allows assessment of esophagogastric junction (EGJ) disruption. While type 3 EGJ predicts definitive gastroesophageal reflux disease (GERD), 2 is less clearly implicated in GERD pathogenesis. This study aimed to characterize physiologic findings determine if the HRM-based Milan Score can define within EGJ.
To investigate whether a lower fraction of inspired oxygen (FiO2) during the early phase lung separation is able to improve overall oxygenation blood assessed by arterial partial pressure (PaO2)/FiO2 ratio, and its effect on collapse postoperative pulmonary complications (PPC). Prospective, nonblinded, randomized controlled trial. Single-center trial at university hospital. Patients scheduled for thoracic surgery requiring one-lung ventilation (OLV). Study participants received either low...
To assess the impact of highly active antiretroviral therapy (HAART) on outcome systemic human immunodeficiency virus-related non-Hodgkin lymphoma (HIV-NHL), we retrospectively analyzed 235 patients in whom HIV-NHL was diagnosed from April 1988 through December 1999. A multivariate Cox proportional hazards model used to estimate prognostic factors for overall survival (OS), progression-free (PFS), and disease-free (DFS). Complete remission occurred 49% patients, 3-year rates OS, PFS, DFS...
Background: Gastroesophageal reflux disease (GERD) is usually associated with disruption of the esophagogastric junction (EGJ). The endoscopic Hill classification has proven to be inadequate assess EGJ integrity. Recently, American Foregut Society (AFS) developed an focused on hiatal hernia (L), opening (D), and flap valve (F). While pH-monitoring remains gold standard for diagnosis GERD, high-resolution manometry (HRM) can anatomy competency. Aim this study validate AFS in patients...
Abstract: Four consecutive patients with a giant leiomyoma originating from the posterior aspect of gastroesophageal junction were treated full-thickness endoscopic retroflex dissection. A complete removal lesion was obtained in all cases. No complications observed except for some degree air filtration causing symptomatic pneumoperitoneum one patient. Retroflex resection at is feasible and safe. Keywords: junction, leiomyoma, submucosal dissection,
In the real-world setting outside clinical trials, neoadjuvant chemoradiation therapy followed by esophagectomy may represent overtreatment in some elderly individuals with multiple comorbidities.Through an observational cohort study, consecutive patients esophageal cancer treated protocol of Chemoradiotherapy for Oesophageal Cancer Followed Surgery Study (CROSS) were compared to similar age who underwent upfront surgery during same study period.Fifty between 2010 and 2017 enrolled....
Ileocolic intussusception due to Burkitt lymphoma is extremely rare in adults. A man aged 17 years presented with a history of recurrent abdominal pain over the past 3 weeks. The abdomen was distended diffuse tenderness, and bowel sounds were present. Abdominal ultrasound CT scans showed evidence small obstruction marked wall thickening ileocecal region ‘target’ signs suggestive for intussusception. At laparoscopy, mass involving caecum terminal ileum found, along multiple locoregional...
Chylotorax is a relatively uncommon and difficult to treat complication after esophagectomy for cancer. We report case of young adult male who underwent neoadjuvant chemoradiationtherapy followed by Ivor-Lewis squamous-cell carcinoma the distal esophagus. During postoperative course patient presented recurrent episodes hemodynamic instability mimicking cardiac tamponade, secondary compression left pulmonary vein atrium mediastinal chylocele. Mediastinal drainage ligation cisterna chyli...
In a previous proof of concept study, transhiatal pleural drain has been shown to be safe and effective after hybrid Ivor Lewis esophagectomy. Aim this study was compare the short-term outcomes intercostal drainage.This is an observational retrospective cohort study. Two methods drainage were compared in patients undergoing Patients treated with connected vacuum bag historical conventional underwater seal suction. Postoperative morbidity, total daily output, serum albumin levels, dose...
Intercostal pleural drainage is standard practice after transthoracic esophagectomy but has some drawbacks. We hypothesized that a transhiatal drain introduced through the subxyphoid port site incision at laparoscopy can be as effective intercostal and may enhance patient recovery.A proof of concept study was designed to assess new method in patients undergoing hybrid Ivor Lewis (laparoscopy right thoracotomy). The main aims were safety efficacy with 15 Fr Blake tube connected portable...
Abstract Background The Oesophago-Gastric Anastomosis Audit (OGAA) is an international collaborative group set up to study anastomotic leak outcomes after oesophagectomy for cancer. This Delphi aimed prioritize future research areas of unmet clinical need in RCTs reduce leaks. Methods A modified process was overseen by the OGAA committee, national leads, and engaged clinicians from high-income countries (HICs) low/middle-income (LMICs). three-stage iterative used topics, including a scoping...
Background: Crural repair is an essential technical component in laparoscopic hiatal hernia surgery, but there no consensus regarding the optimal method to prevent postoperative recurrence. Mesh augmentation, especially with permanent materials, associated dysphagia and complications. The rotational falciform ligament flap (FLF) has been reported be effective reinforcing standard suture closure of hiatus. Materials Methods: Patients primary or secondary whom FLF was used buttress hiatus were...