- Spine and Intervertebral Disc Pathology
- Bone health and osteoporosis research
- Sleep and related disorders
- Liver Disease Diagnosis and Treatment
- Adipokines, Inflammation, and Metabolic Diseases
- Infectious Diseases and Tuberculosis
- Cardiovascular Disease and Adiposity
- Heavy Metal Exposure and Toxicity
- Nutrition and Health in Aging
- Adipose Tissue and Metabolism
- Bone Metabolism and Diseases
- NF-κB Signaling Pathways
- Musculoskeletal pain and rehabilitation
- Trace Elements in Health
- Folate and B Vitamins Research
- Medical Imaging and Analysis
- Orthopedic Infections and Treatments
- Genetic Associations and Epidemiology
- RNA regulation and disease
The Affiliated Yongchuan Hospital of Chongqing Medical University
2020-2024
Chongqing Medical University
2020-2024
Xiangya Hospital Central South University
2022
Central South University
2022
Purpose It has been reported that bone is the primary organ for manganese (Mn) accumulation, but association between and loss remains debatable. Therefore, this study aimed to evaluate relationship blood mineral density/bone content (BMD/BMC) by using a representative sample from National Health Nutrition Examination Survey (NHANES). Methods A total of 9732 subjects over age 18 with available data were enrolled in study. The BMD/BMC body, spine femoral regions was evaluated multivariate...
Abstract Circulating adiponectin shows some relationships with the occurrence of cardiometabolic diseases and osteoporotic fracture, but little is known about their causal associations. This two-sample Mendelian randomization (MR) study aims to explore roles circulating in fracture. We used 15 single nucleotide polymorphisms associated as instrumental variables. Inverse variance weighted, weighted median MR-Egger regression methods were applied The results found that high was causally...
Sleep duration suggests some association with osteoporosis and cardiometabolic diseases, but it is unknown if these associations are causal or confounded. In this two-sample Mendelian randomization (MR) study, we included the largest genome-wide studies (GWASs) associated sleep outcome measures of diseases. Finally, 25 single nucleotide polymorphisms (SNPs) short 7 SNPs long obtained significance (P < 5 × 10-8) were used as instrumental variables. Genetic predisposition to was strongly...
The causal roles of muscle weakness in cardiometabolic diseases and osteoporosis remain elusive. This two-sample Mendelian randomization (MR) study aims to explore the risk osteoporosis. 15 single nucleotide polymorphisms (SNPs, P < 5 × 10-8) associated with were used as instrumental variables. Genetic predisposition led increased coronary artery disease (inverse variance weighted [IVW] analysis, beta-estimate: 0.095, 95% confidence interval [CI]: 0.023 0.166, standard error [SE]:0.036,...
Abstract Background Many types of bone grafting have been reported for successful use in achieving anterior column support and fusion after one stage posterior debridement the treatment lumbar spinal tuberculosis. However, none-structural has rarely studied. This study was aimed to identify feasibility from comparing advantages disadvantages with structural Patients methods We retrospectively reviewed patients tuberculosis who had undergone (n=27) (n=22) single-stage instrumentation at least...
Abstract Purpose: To assess the availability of oblique lumbar interbody fusion at level L5-S1 (OLIF51) and to choose ideal surgical corridor in OLIF51 by introducing V-line. Methods: The axial views through center disc were reviewed. We adopt 18mm as width simulated corridor. midline is disc. According traction distance left iliac vein (LCIV) psoas major (PM), we defined all subjects V (+) (traction-difficultly LCIV), (-) (traction-friendly P PM) PM). V-line was a straight line dividing...