A5100369456- Esophageal Cancer Research and Treatment
- Cancer-related molecular mechanisms research
- Autophagy in Disease and Therapy
- RNA modifications and cancer
- Cancer Immunotherapy and Biomarkers
- Gastric Cancer Management and Outcomes
- Ferroptosis and cancer prognosis
- Pain Mechanisms and Treatments
- Pesticide Residue Analysis and Safety
- Cervical Cancer and HPV Research
- Transplantation: Methods and Outcomes
- Appendicitis Diagnosis and Management
- Intraperitoneal and Appendiceal Malignancies
- Mast cells and histamine
- Cardiovascular Disease and Adiposity
- Uterine Myomas and Treatments
- Cancer-related gene regulation
- Urban and spatial planning
- Colorectal Cancer Treatments and Studies
- Head and Neck Surgical Oncology
- Metastasis and carcinoma case studies
- Histone Deacetylase Inhibitors Research
- Ophthalmology and Visual Impairment Studies
- Minimally Invasive Surgical Techniques
- Energy, Environment, Agriculture Analysis
Wenzhou Medical University
2024
Guangdong Medical College
2023
Yangzhou University
2012-2022
Sun Yat-sen University
2017-2022
Southwest Medical University
2014-2022
The First Affiliated Hospital, Sun Yat-sen University
2017-2022
Nantong Tumor Hospital
2012
Abstract Cholesterol metabolism is highly correlated with risks of pancreatic ductal adenocarcinoma (PDAC). Nevertheless, the underlying mechanisms activation cholesterol biogenesis remain inconclusive. KIF11 a key component bipolar spindle and expresses in various malignancies. However, its functional role PDAC tumorigenesis still unclear. This study aims to elucidate oncogenic functions stimulating metabolism, thereby driving progression. We utilized bioinformatics analysis identify that...
Abstract Single‐nucleotide polymorphisms (SNPs) of TERT rs2736098, rs2736100, and CLPTM1L rs402710 at 5p15.33 are significantly associated with risk a spectrum cancers. However, cervical cancer has been rarely evaluated. In this study, we genotyped the three SNPs in case–control study 1,033 cases 1,053 cancer‐free controls Chinese population. Logistic regression analyses showed that two both recessive model (rs2736098, AA vs. AG/GG: adjusted OR = 1.35, 95% CI 1.06–1.72; CC AC/AA: 1.38,...
A sensitive and robust method is presented for the simultaneous determination of amoxicillin (AMO) ampicillin (AMP) in eggs by reversed-phase high-performance liquid chromatography with fluorescence detection (RP-HPLC-FLD). This used a simple liquid-liquid extraction samples acetonitrile dichloromethane as precipitation proteins solvent. AMO AMP reacted salicylaldehyde to form fluorescent derivatives, which were then analyzed RP-HPLC-FLD. Separation was carried out on an Athena C18 column...
Abstract Circulating adiponectin shows some relationships with the occurrence of cardiometabolic diseases and osteoporotic fracture, but little is known about their causal associations. This two-sample Mendelian randomization (MR) study aims to explore roles circulating in fracture. We used 15 single nucleotide polymorphisms associated as instrumental variables. Inverse variance weighted, weighted median MR-Egger regression methods were applied The results found that high was causally...
In the current practice, graft ischaemia and reperfusion injury (IRI) is considered an inevitable component in organ transplantation, contributes to compromised quality, inferior survival limitations availability. Among all donor organs, heart most vulnerable IRI tolerated ischaemic time shortest.By combining adapted surgical techniques normothermic machine perfusion (NMP), we performed first case of ischaemia-free beating transplantation (IFBHT) man. The was procured after situ NMP circuit...
The aim of this study was to investigate the effects JS-K, a nitric oxide donor prodrug, on DNA damage and autophagy in bladder cancer (BCa) cells explore potential related mechanisms.Through detecting proliferation viability, cell morphology observation colony formation assay low concentrations JS-K significantly inhibited BCa growth while having no effect normal cells.JS-K induced an increase level protein γH2AX decrease repair-related proteins PCNA RAD51 cells, indicating that can induce...
AIM: To compare the consistency of two autorefractors (Tianle RM-9000 and Topcon KR-800) for school-age myopia children, to provide a basis largescale data analysis comparison. METHODS: The refractive error in 909 subjects (age 4–18y) were measured using both without cycloplegia. analyzed Fourier decomposition correlation coefficients, intraclass coefficients (ICC), Bland-Altman limits agreement (LoA) each parameter calculated. RESULTS: There was strong between spherical equivalent (SE),...
Aims: This study aimed to retrospectively determine the influence factors and survival effects of chemotherapy in pathological T3N0M0 esophageal cancer (EC) patients based on histological type. Methods: A total 1136 EC who had surgery were chosen from Surveillance, Epidemiology End Results database. The divided into subgroups type status. Multivariate logistic regression, log-rank test Cox regression used identify prognostic risk differences. propensity score matching analysis was applied...
Autophagy is considered to be closely associated with cancer, functioning as either an anticancer or procancer mechanism depending on the cancer stage. However, prognostic value of autophagy papillary renal cell carcinoma (pRCC) remains unclear. In this study, our purpose was determine autophagy-related mRNA signature predict overall survival patients pRCC.A total 284 pathologic confirmed pRCC in The Cancer Genome Atlas (TCGA) dataset were recruited and included. We choose who have smoked...
Objective To investigate the status of breast reconstruction in cancer patients, and to explore relevant factors affecting recognized degree reconstruction. Methods Based on current hospital-based survey design, six hundred patients with postoperative from February August 2016 were collected First Affiliated Hospital Sun Yat-sen University,including their demographic characteristics, quality life, social support recognition reconstruction. Multivariate logistic regression model was...
Objective To investigate the clinical efficacy and safety of re-radiotherapy combined with TS-1 (tegafur gimeracil oteracil potassium capsule) in treatment local recurrent esophageal carcinoma. Methods A total 63 carcinoma patients who recurred after first course radiation admitted to Jiangdu People′s Hospital Yangzhou during January 1, 2012 June 30, 2015 were retrospec-tively analyzed. Twenty-seven them treated deemed as research group 36 radiotherapy alone control based on...