A5100725486- Cardiac Ischemia and Reperfusion
- Evaluation Methods in Various Fields
- Cardiac Arrest and Resuscitation
- MicroRNA in disease regulation
- Target Tracking and Data Fusion in Sensor Networks
- Anesthesia and Neurotoxicity Research
- Organ Transplantation Techniques and Outcomes
- Cancer-related molecular mechanisms research
- Advanced Decision-Making Techniques
- Circular RNAs in diseases
- GNSS positioning and interference
- Inertial Sensor and Navigation
- Anesthesia and Pain Management
- Thermal Regulation in Medicine
- Dialysis and Renal Disease Management
- Acute Kidney Injury Research
- Galectins and Cancer Biology
- Organ Donation and Transplantation
- RNA regulation and disease
- Advanced Glycation End Products research
- Cardiac Imaging and Diagnostics
- RNA modifications and cancer
- Esophageal Cancer Research and Treatment
- Pharmacological Effects and Toxicity Studies
- NF-κB Signaling Pathways
Southwest Forestry University
2023-2024
The First Affiliated Hospital, Sun Yat-sen University
2010-2022
Sun Yat-sen University
2011-2022
Beijing University of Technology
2009-2016
China Medical University
2015
Chengdu Military General Hospital
2012
Kunming General Hospital of Chengdu Military Command
2012
University of Electronic Science and Technology of China
2008-2011
Zhaotong University
2010
Structural changes of the left and right atria associated with atrial fibrillation (AF) in mitral stenosis (MS) patients are well known, alterations microRNA (miRNA) expression profiles have also been investigated. However, miRNA still require delineation. This study evaluated tissues from MS AF relative to those normal sinus rhythm (NSR). Sample appendages were obtained 12 (6 AF) during valve replacement surgery. From these tissues, created analyzed using a human microarray. Results...
Fibronectin (FN) is a high-molecular-weight glycoprotein component of the extracellular matrix involved in cell adhesion, migration, metastasis, proliferation and differentiation, as well embryogenesis, wound healing, blood coagulation. Considerable recent research has established that tumor expression FN closely associated with formation development disease prognosis. However, mechanisms underlying this relationship have remained unclear. The aim study was to investigate protein esophageal...
Plenty of studies have established that dysregulation autophagy plays an essential role in cancer progression. The autophagy-related proteins been reported to be closely associated with human patients' prognosis. We explored the expression dynamics and prognostic value protein ULK1 by immunochemistry (IHC) method two independent cohorts nasopharygeal carcinoma (NPC) cases. X-tile program was applied determine optimal cut-off training cohort. This derived cutoff then subjected analysis...
The atrial fibrillation (AF) associated microRNAs (miRNAs) were found in the right atrium (RA) and left (LA) from patients with rheumatic mitral valve disease (RMVD). However, most studies only focus on RA; potential differences of AF-associated miRNAs between RA LA are still unknown. aim this study was to perform miRNA expression profiles analysis compare appendages (RAA) (LAA) RMVD patients.Samples tissues RAA LAA obtained 18 (10 AF) during replacement surgery. From these tissues, created...
Automated fruit-picking equipment has the potential to significantly enhance efficiency of picking. Accurate detection and localization fruits are particularly crucial in this regard. However, current methods rely on expensive tools such as depth cameras LiDAR. This study proposes a low-cost method based monocular images achieve target estimation. To improve accuracy targets, especially small an advanced YOLOv8s algorithm is introduced. approach utilizes BiFormer block, attention mechanism...
Abstract Background MicroRNAs were enrolled in various cardiovascular disease especially ischemic heart diseases, but the microRNA changes during myocardial ischemia reperfusion injury underwent cardiopulmonary bypass are still unknown. This study screens differences CPB canines and evaluates relationship of microRNAs with injury. Methods 13 healthy received 60 minutes aortic clamping cardioplegic arrest, followed by 90 reperfusion. Left ventricular samples, blood samples hemodynamic data...
Abstract Guanine nucleotide binding protein alpha 13 (GNA13) has been found to play critical roles in the development of several human cancers. However, little is known about GNA13 expression and its clinical significance hepatocellular carcinoma (HCC). In our study, was reported be significantly up-regulated HCC tissues, this correlated with clinicopathological parameters, including tumor multiplicity (P = 0.004), TNM stage 0.002), BCLC 0.010). Further Cox regression analysis suggested that...
Although there are substantial analyses for association of coronary artery disease (CAD) with diabetic retinopathy (DR), which was recognized as an indicator risk CAD in diabetes mellitus (DM), is yet little rigorous evaluation the relationship between DR and subclinical atherosclerosis (CAS) determined by 64-slice multidetector computed tomography angiography (MDCTA) persons type 2 DM. In this article, we found that CAS associated independent traditional factors [odds ratio (OR): 5.1; 95%...
This study aimed to investigate whether selective antegrade cerebral perfusion or retrograde is a better technique for brain protection in deep hypothermic circulatory arrest by obtaining metabolic evidence from microdialysis.Randomized, animal study.Assisted circulation laboratory.Eighteen piglets of either sex (9.8 ± 3.1 kg).Animals were randomly assigned 40 minutes at 18°C without (deep group, n = 6) with (selective (retrograde 6). Reperfusion was continued 3 hours.Microdialysis (glucose,...
Background Healthcare-acquired Pseudomonas aeruginosa (P. aeruginosa) infections in the Pediatric Intensive Care Unit (PICU), which have a high incidence, increase treatment costs and mortality, seriously threaten safety of critically ill children. It is essential to seek convenient effective methods control prevent healthcare-acquired (HAIs). This research was conducted study effect infection nurses on occurrence P. HAIs multi-drug resistance (MDR) strains PICU. Methods The clinical data...
In the current practice, graft ischaemia and reperfusion injury (IRI) is considered an inevitable component in organ transplantation, contributes to compromised quality, inferior survival limitations availability. Among all donor organs, heart most vulnerable IRI tolerated ischaemic time shortest.By combining adapted surgical techniques normothermic machine perfusion (NMP), we performed first case of ischaemia-free beating transplantation (IFBHT) man. The was procured after situ NMP circuit...
For the purpose of creating excellent walking environment, increasing proportion pedestrians and providing a planning designing basis for newly-built rebuilt sidewalks, this paper proposed comprehensive multi-factor evaluation method pedestrian level service on sidewalks based quantification environmental factors. Firstly, pedestrians' satisfaction questionnaires survey was conducted with intercept 87 typical covering different regions, road grades, facility conditions. The rating scale form...
Abstract Interleukin (IL)-10-producing B cells (B10 cells) plays an important role in the tumor tolerance. High frequency of peripheral B10 cell was reported patients with lung cancer recently. Micro RNA (miR) regulates some gene expression. This study test a hypothesis that miR-98 suppresses expression IL-10 subjects cancer. The results showed levels were significantly less than healthy subjects. mRNA higher as compared controls. A negative correlation identified between and cells. Serum...
Restricting oxygen delivery during the reperfusion phase of cardiopulmonary bypass (CPB) protects heart, but effects on lung ischemia (IR) in CPB are unknown. We examined whether extracellular high mobility group box 1 (HMGB1) mediated inflammation early IR injury CPB. Fourteen healthy canines received with 60 minutes aortic clamping and cardioplegic arrest, followed by 90 reperfusion. Following surgery, animals were randomized into control (n = 7) or test groups. Control a constant level...
Nicorandil in reducing contrast-induced nephropathy (CIN) following elective percutaneous coronary intervention (PCI) is an inconsistent practice. This article aims to evaluate the efficacy and safety of nicorandil preventing CIN after PCI.This a pooled analysis patients treated with PCI. The primary outcome was incidence CIN. secondary outcomes were major adverse events, including mortality, heart failure, recurrent myocardial infarction, stroke, renal replacement therapy.A total 1229...
A positioning algorithm based on a Kalman smoother is proposed, and the performance of INS/GPS integrated navigation system improved. In this paper, error sources inertial (INS) Global Positioning System (GPS) are analyzed respectively, then state models set up. Furthermore, information GPS INS modeled simulated, using KF Rauch-Tung-smoother (RTS) filtering compared. The numerical emulation demonstrates that RTS can greatly enhance robustness reliability system. has obvious advantages high accuracy.
Protein tyrosine phosphatase 4A2 (PTP4A2) has been implicated as an oncogenic protein in several human cancers. However, the level of PTP4A2 expression and its prognostic significance nasopharyngeal carcinoma (NPC) remains unknown. In this study, Western blotting (WB), quantitative real-time PCR (qT-PCR) immunohischemistry (IHC) was applied to evaluated levels NPC cell lines tumor tissues combining two independent cohorts. Receiver-operator curve (ROC) analysis used assessed optimal cut-off...