Benjamin Pariente
A5102997049- Inflammatory Bowel Disease
- Microscopic Colitis
- Diverticular Disease and Complications
- Gastric Cancer Management and Outcomes
- Autoimmune and Inflammatory Disorders
- Colorectal Cancer Surgical Treatments
- Eosinophilic Esophagitis
- Diagnosis and treatment of tuberculosis
- Immune Cell Function and Interaction
- Adolescent and Pediatric Healthcare
- Helicobacter pylori-related gastroenterology studies
- Gastrointestinal motility and disorders
Université de Lille
2019-2021
Centre Hospitalier Universitaire de Lille
2019-2021
Hôpital Claude Huriez
2018-2020
Lille Inflammation Research International Center
2019
Following ileal resection for Crohn's disease (CD), recurrence is very frequent. Although several clinical risk factors of have been identified, predicting relapse remains challenging. Performing an ileocolonoscopy within the first year after surgery currently recommended to assess endoscopic and adjust treatment. We took advantage a large prospective multicentric cohort investigate role mucosa-associated microbiota in postoperative recurrence. Ileal was analysed by 16S sequencing at time...
INTRODUCTION: Early ileocolonoscopy within the first year after surgery is gold standard to evaluate recurrence ileocolonic resection for Crohn's disease (CD). The aim of study was association between presence and severity anastomotic ileal lesions at early postoperative long-term outcomes. METHODS: REMIND group conducted a prospective multicenter study. Patients operated or CD were included. An performed 6 months surgery. endoscopic score describing separately built. Clinical relapse...
Abstract Background Preventing postoperative recurrence (POR) is a major concern in Crohn's disease (CD). While azathioprine an option, no data available on ustekinumab efficacy this situation. Aims We compared the effectiveness of versus preventing endoscopic POR CD. Methods retrospectively collected from all consecutive CD patients treated with after intestinal resection 9 centers. The control group (azathioprine alone) was composed who participated randomized controlled trial conducted...
T cell clonal expansions are present in the inflamed mucosa of patients with Crohn’s disease (CD) and may be implicated postoperative recurrence after ileocolonic resection. Methods receptor (TCR) analysis was performed 57 included a prospective multicentre cohort. Endoscopic defined by Rutgeerts score >i0. DNA mRNA were extracted from biopsies collected surgical specimen endoscopy, analysed high throughput sequencing microarray, respectively. Results TCR repertoire CD displayed diverse...
Fatigue is commonly reported by patients with inflammatory bowel disease [IBD], but the determinants of IBD-related fatigue have yet to be determined. To identify factors associated in a large population IBD. and nine other disability dimensions were assessed cohort 1704 consecutive IBD using IBD-disk questionnaire cross-sectional survey 42 French Belgian centres. severe defined as energy subscores >5 >7, respectively. Determinants univariate multivariate analyses (odds ratios [ORs] are...
Better patient knowledge on inflammatory bowel disease [IBD] could improve outcome and quality of life. The aim this study was to assess if an education programme improves IBD patients' skills as regards their disease.The GETAID group conducted a prospective multicentre randomised controlled study. patients were included at diagnosis, or after significant event in the course. Patients between 'educated' control groups for 6 months. Education performed by trained health care professionals. A...
Abstract Background Early ileocolonoscopy within the first year after surgery is gold standard to evaluate post-operative recurrence ileocolonic resection for Crohn’s disease (CD). The aim of study was association between lesions at 6 months and long-term outcomes. Methods REMIND group conducted a prospective multicentre study. Patients operated ileal or CD were included. An performed surgery. endoscopic classification separating anastomotic built (Ax lesions; Ix neo-terminal ileum evaluated...
Early detection of postoperative recurrence (POR) remains a major concern in patients with Crohn’s disease (CD). We aimed to assess the performances serial faecal calprotectin (Fcal) monitoring within three first months following ileocolonic resection predict CD endoscopic POR at 6 months. In this multi-centre prospective study, who underwent were consecutively enrolled. Stools samples collected baseline, 1 month (M1) and M3 measure Fcal level. The stools morning day before endoscopy reduce...
Background: Crohn's disease displays heterogeneity in terms of location, progression and response to treatment. Most patients require an intestinal resection due complicated disease, a majority them will experience recurrence. We aimed characterize biological pathways driving postoperative recurrence identify predictors which could guide therapeutic management. Methods: In this multicentre prospective study, we conducted transcriptome analysis on ileal mucosa CD undergoing ileocolonic...