A5015426456- Anorectal Disease Treatments and Outcomes
- Pelvic floor disorders treatments
- Colorectal and Anal Carcinomas
- Cervical Cancer and HPV Research
- Diverticular Disease and Complications
- Colorectal Cancer Surgical Treatments
- Diagnosis and treatment of tuberculosis
- Genital Health and Disease
- Inflammatory Bowel Disease
- Sepsis Diagnosis and Treatment
- Hernia repair and management
- Intensive Care Unit Cognitive Disorders
- Microscopic Colitis
- Respiratory Support and Mechanisms
- Biliary and Gastrointestinal Fistulas
- COVID-19 Clinical Research Studies
- Urinary Bladder and Prostate Research
- Nonmelanoma Skin Cancer Studies
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Viral-associated cancers and disorders
- Congenital gastrointestinal and neural anomalies
- Musculoskeletal pain and rehabilitation
- Myofascial pain diagnosis and treatment
- Nosocomial Infections in ICU
- Therapeutic Uses of Natural Elements
Groupe Hospitalier Diaconesses Croix Saint-Simon
2015-2025
Hôpital des Diaconesses
2002-2014
Hôpital Bichat-Claude-Bernard
2003-2010
Délégation Paris 6
2004-2009
Hôpital Lariboisière
2004
Inserm
2003
Université Claude Bernard Lyon 1
2003
Assistance Publique – Hôpitaux de Paris
2003
Pfizer (United States)
2000
University of Illinois Chicago
2000
The objective of this study was to show that although transcutaneous electrical tibial nerve stimulation (TENS) is being increasingly used treat fecal incontinence (FI), its efficacy has never been proved using controlled trials.In randomized, double-blind, sham-controlled trial, 144 patients aged 30-82 years from nine centers were randomly assigned receive either active or sham stimulations for 3 months. primary end point the response treatment based on number and urgency episodes....
This prospective study evaluated the efficacy and safety of local formalin application in chronic refractory radiation-induced hemorrhagic proctitis.All patients were treated under anesthesia by direct 4 percent to affected rectal areas.The included 33 (17 women) was conducted between January 1994 December 2001. There 11 anal cancers (33 percent), prostate cancers, 9 cervical or endometrial 1 bladder cancer, cancer. The mean number daily bleeds 2.7 (range, 0.5-15). Nineteen (58 percent)...
Abstract Background Understanding the natural history of anal high-risk human papillomavirus (hrHPV) infection is key for designing cancer prevention programs but has not been systematically characterized. Methods We reanalyzed data from 34 studies including 16 164 individuals in 6 risk groups defined by immunodeficiency virus (HIV) status, sex, and male sexuality: men who have sex with (MSM) people HIV (MSMWH), HIV-negative MSM, women (WWH), women, (MSW) (MSWWH), MSW. used Markov models to...
The role of antibiotics in preventing fistula formation following an initial abscess remains a subject debate. This study compared the incidence ano patients experiencing their first episode acute perianal sepsis, with and without antibiotic therapy, evaluated prevalence necessitating surgical intervention at 1 year. retrospective cohort was conducted tertiary care hospital dedicated proctology department. All who presented to emergency unit sepsis were eligible for inclusion. included 276...
ABSTRACT Background The efficacy and safety of intrarectal botulinum toxin A (BoNT/A) injections in patients with urge fecal incontinence (FI) were evidenced a large, multicenter, randomized, placebo‐controlled study (FI‐TOXIN). aims the present to evaluate long‐term BoNT/A real‐world setting who participated FI‐TOXIN study. Methods Data collected from had previously 8 French centers November 2015 2020 retrospectively analyzed. Given transient effect BoNT/A, received first injection could be...
The study aimed to evaluate the efficacy of fibrin glue in treatment complex anal fistula.Thirty consecutive patients with a fistula underwent instillation after an 8 week period seton drainage. Cure was defined as complete closure any secondary opening, absence seepage, and no abscess formation.The mean age (15 males) 40.5 (range, 22.8-69.1) years. duration follow-up 11.7 0.2-33.5) months. Complete achieved 17 at 1 month but two delayed occurred. At end follow-up, 15 (50%) were considered...
Although human immunodeficiency virus (HIV)-infected women are at high risk for anal cancer, few data have been published on prevalence of and factors precancer potential screening strategies in this group. A cross-sectional study was nested a gynecological cohort HIV-infected women. Anal swab specimens were collected cytology papillomavirus (HPV) testing. High-resolution anoscopy, with biopsy when indicated, systematically performed. Among the 171 enrolled women, median age 47.3 years 98%...
Objective Endocuff Vision (ECV) is the second generation of a device designed to improve polyp detection. The aim this study was evaluate its impact on adenoma detection rate (ADR) in routine colonoscopy. Design This cluster-randomised crossover trial compared Endocuff-assisted (ECV+) with standard (ECV-) Two teams 11 endoscopists each prior ECV experience, balanced terms basal ADR, gender and case volume were compared. In randomised fashion, started ECV+ or ECV- switched group after...
We assessed prevalence and risk factors for anal human papillomavirus (HPV) in immunodeficiency virus (HIV)-positive men who have sex with (MSM), are at high-risk of HPV-related cancer.
Several cases of acute colitis induced by non-steroidal anti-inflammatory drugs (NSAIDs) have been reported but the general role recent NSAID intake as a risk factor for diarrhoea has not studied to date. The aim our study was determine whether is increased NSAIDs in prospective series which were seen practitioners France and serious enough require stool culture. Patients, physicians, methods: A total 285 consecutive patients with diarrhoea, Sentinel (GPs) between December 1998 July 1999,...
PURPOSE: This study was designed to estimate the prevalence of anal sphincter injury after forceps delivery in a large population females managed by trained obstetricians French hospital and identify factors predictive for injury. METHODS: We performed prospective healthy older than 18 years with no history incontinence, anorectal abnormalities, or surgery their first vaginal delivery. All were interviewed using standardized questionnaire concerning intestinal transit continence status....
High-resolution anoscopy (HRA) is a useful screening tool for anal intraepithelial neoplasia (AIN), although reputedly challenging interpretation of suspected lesions.All consecutive patients who underwent biopsies at least 1 lesion suspicious AIN during HRA from November 2010 to March 2012 were prospectively included. The characteristics (borders, staining with acetic acid and Lugol iodine solution, patterns epithelium vascularization) the lesions detected compared histology.A total 168...
The clinicopathological and virological characteristics of anal superficially invasive squamous-cell carcinoma (SISCCA) were determined.Seventeen patients with a completely excised stage T1N0M0 (SCC) included in the study. tumours divided into invasive. Patients high-grade squamous intraepithelial dysplasia, which corresponded to neoplasia (AIN) Grades 2 or 3, used as control group. Clinicopathological investigated. Overall survival cancer recurrence-free also assessed.Of 17 patients, 12...
Background. Little is known about the type-specific prevalence of anal human papillomavirus (HPV) infection and risk factors for high-risk (HR) HPV in immunodeficiency virus (HIV)–infected women. Methods. A cross-sectional study cervical was nested within a gynecological cohort HIV-infected Specimens were tested DNA using polymerase chain reaction–based assay. Results. The population consisted 311 women with median age 45.3 years, whom 42.8% originated from sub-Saharan Africa 96.8% receiving...
To assess determinants for histologically proven high-grade anal intraepithelial lesions (hHSIL) in HIV-positive men who have sex with (MSM), a population at high-risk of HPV-related cancer.
This prospective study was designed to describe a typical attack of proctalgia fugax.Patients were recruited from May 2003 June 2004. Whatever the reason for consultation, they systematically asked: "Do you ever suffer intermittent and recurring anorectal pain lasting at least three seconds?" If answer yes, interviewed with questionnaire had proctologic examination. The criterion fugax positive negative examination.The included 1,809 patients. Fifty-four these patients (3 percent) 83 percent...
This study evaluated the validity of endorectal ultrasonography in predicting rectal infiltration patients with deep pelvic endometriosis.Patients were recruited consecutively Department Surgical Gynecology Diaconesses Hospital from April 1996 to July 2003. Inclusion criteria suspicion endometriosis on basis outpatient history and/or clinical symptoms a mass palpable bimanual examination that might infiltrate wall. There no exclusion criteria. Endorectal was performed by same investigator...
Abstract BACKGROUND: The performance of cytologic screening and its correlation with histology polymerase chain reaction (PCR) detection human papillomavirus (HPV) DNA have not been evaluated in populations a low prevalence anal intraepithelial neoplasia (AIN). objective the current study was to analyze significance abnormal smears relative PCR HPV DNA. METHODS: A smear viral sample were taken 300 consecutive patients undergoing surgery (Milligan‐Morgan hemorrhoidectomy and/or fissurectomy)...
Objective: The aim of this study was to assess the effectiveness sacral nerve modulation (SNM) in a large cohort patients implanted for at least 10 years, quantify adverse event rates, and identify predictive factors long-term success. Summary Background Data: Few studies have evaluated success SNM. Methods: Data collected prospectively from fecal incontinence (FI) 7 French centers between January 1998 December 2008 were retrospectively analyzed. Patient FI severity scores assessed before...
To prospectively evaluate the long-term results and assess patient satisfaction after stapled haemorrhoidopexy (HS).A total of 150 patients (121 male patients) with symptomatic grade II (n = 50) or III 100) haemorrhoids underwent HS. Patients were followed up during consultations at regular intervals, allowing prospective data collection. A final telephone follow was also undertaken.Follow obtained for 130 (86.6%). After a median 39 months (range, 12-72), 90% fully satisfied 92% free...