A5050036392- Cardiovascular and Diving-Related Complications
- High Altitude and Hypoxia
- Spaceflight effects on biology
- Hemodynamic Monitoring and Therapy
- Cardiac Arrest and Resuscitation
- Heart Rate Variability and Autonomic Control
- Diabetic Foot Ulcer Assessment and Management
- Respiratory Support and Mechanisms
- Exercise and Physiological Responses
- Airway Management and Intubation Techniques
- Cardiovascular and exercise physiology
- Ultrasound in Clinical Applications
- Non-Invasive Vital Sign Monitoring
- Optical Imaging and Spectroscopy Techniques
- Transplantation: Methods and Outcomes
- Oral microbiology and periodontitis research
- Pneumocystis jirovecii pneumonia detection and treatment
- Alcohol Consumption and Health Effects
- Heme Oxygenase-1 and Carbon Monoxide
- Long-Term Effects of COVID-19
- Occupational Health and Performance
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Oral health in cancer treatment
- Bone and Joint Diseases
- Medical and Biological Ozone Research
University of Padua
2021-2025
Azienda Ospedaliera di Padova
2023
National Research Council
2021
Long COVID-19 patients show systemic inflammation and persistent symptoms such as fatigue malaise, profoundly affecting their quality of life. Since improving oxygenation can oppose at multiple tissue levels, we hypothesized that hyperbaric oxygen therapy (HBOT) could arrest progression thus relieve COVID-19. We evaluated oxy-inflammation biomarkers in long subjects treated with HBOT monitored non-invasive methods. Five (two athletes three other comorbidities) were assigned to receive HBOT:...
Exercise generates reactive oxygen species (ROS), creating a redox imbalance towards oxidation when inadequately intense. Normobaric and hyperbaric (HBO) breathed while not exercising induces antioxidant enzymes expression, but literature is still poor. Twenty-two athletes were assigned to five groups: controls; 30%, or 50% O2; 100% O2 at 1.5 2.5 atmosphere absolute (ATA). Twenty treatments administered on non-training days. Biological samples collected T0 (baseline), T1 (end of treatments),...
Abstract Competitive Offshore Ocean Sailing is a highly demanding activity in which subjects are exposed to psychophysical stressors for long time. To better define the physiological adaptations, we investigated stress response of 3-days ocean navigation with disruption circadian rhythms. 6 male were involved study and provided urine saliva samples before setting sail, during single day inshore sailing, navigation, at arrival, measure oxidative stress, cortisol, nitric oxide metabolites...
Divers can experience cognitive impairment due to inert gas narcosis (IGN) at depth. Brain-derived neurotrophic factor (BDNF) rules neuronal connectivity/metabolism maintain function and protect tissues against oxidative stress (OxS). Dopamine glutamate enhance BDNF bioavailability. Thus, we hypothesized that lower circulating levels (via lessened dopamine and/or release) underpin IGN in divers, while testing if loss is associated with increased OxS.To mimic IGN, administered a deep test via...
Pulmonary gas exchange in breath-hold diving (BHD) consists of a progressive increase arterial partial pressures oxygen ([Formula: see text]) and carbon dioxide during descent. However, recent findings have demonstrated that [Formula: text] does not consistently rise all subjects. This study aimed at verifying explaining derangements BHD analyzing blood gases searching for pulmonary alterations with lung ultrasound. After ethical approval, 14 fit divers were included. Experiments performed...
Background: Alcohol abuse is one of the most common causes mortality worldwide. This study aimed to investigate efficacy a treatment in reducing circulating ethanol and oxidative stress biomarkers. Methods: Twenty wine-drinking subjects were investigated randomized controlled, single-blind trial (ClinicalTrials.gov. Identifier: NCT06548503; Ethical Committee University Padova (HEC-DSB/12-2023) evaluate effect intake product containing silymarin, pyrroloquinoline quinone sodium salt,...
Abstract Purpose Human presence in space is increasingly frequent, but we must not forget that it a hostile environment. We aimed to study the characteristics of experimental scenarios, obtain data on human response isolation, disruption circadian rhythm and high levels psychophysical stress. Methods In these experiments, evaluated stress five young healthy subjects inside an earth-based moon-settlement-like habitat during 1-week long analog astronaut mission. Wearable devices were used...
Implantation is currently the best option for tooth replacement in periodontitis. Some major contraindications immediate implant are acute periodontitis and active infection. We present case of a 51-year-old female patient with highest grade stage treated advanced platelet-rich fibrin-enriched zirconia implants hyperbaric oxygen therapy (HBOT). In particular, HBOT before after implantation promoted bone regeneration integration, also providing an antiseptic effect. After six months, were...
Hypoxia and hyperoxia are both worrisome issues potentially affecting SCUBA divers, but validated methods to monitor these two conditions underwater still lacking. In this experiment, a volunteer diver was equipped with pulse oximeter detect peripheral oxygen saturation (SpO2) device the reserve index (ORi™). ORi™ values were compared arterial blood (SaO2) partial pressure of (PaO2) obtained from cannulated right radial artery at three steps: rest out water; −15 m after pedaling on submerged...
SignificancePulse oximetry estimates the arterial oxygen saturation of hemoglobin (SaO2) based on relative changes in light intensity at cardiac frequency. Commercial pulse oximeters require empirical calibration healthy volunteers, resulting limited accuracy low levels. An accurate, self-calibrated method for estimating SaO2 is needed to improve patient monitoring and diagnosis.AimGiven challenges levels, we pursued creation a algorithm that can effectively estimate across its full range....
While existing literature covers significant detail on the physiology of human freediving, lack standardized protocols has hindered comparisons due to confounding variables such as exercise and depth. By accounting for these variables, direct depth-dependent impacts cardiovascular blood oxygen regulation can be investigated. In this study, effects 1) cerebral hemodynamic oxygenation changes, 2) arterial saturation (SpO 2 ), 3) heart rate during breath-hold diving without were Six freedivers...
SCUBA diving poses risks due to pressure changes during descent (compression) and ascent (decompression). Decompression sickness (DCS) occurs gas bubble formation as the decreases, causing joint pain, numbness, dizziness, or even paralysis death. Immediate treatment involves 100% oxygen help eliminate inert gases hyperbaric therapy (HBOT), which is essential reduce emboli inflammation, thus improving symptoms. We evaluated oxy-inflammation biomarkers in saliva urine of nine subjects pre-...
Background Current diving physiology postulates that SCUBA divers’ arterial blood gas (ABG) levels vary proportionally to environmental pressure, but, date, ABGs have only been obtained during simulated dives. Also, recent evidence supports the use of arterial/alveolar (a:A) partial pressures oxygen (PO 2 ) ratio predict PO (PaO under hyperbaric conditions from measurements at 1 atmosphere absolute (ATA). This work summarizes in divers real underwater and aims validate a:A predicting PaO...
Background: Scant data are available on nutritional status in bilateral lung transplant (BLT) candidates. Methods: All consecutive recipients admitted to the intensive care unit (ICU) of University Hospital Padua (February 2016–2020) after bilateral-lung were retrospectively screened. Data collected: (i) indices (body mass index (BMI), albumin level, prognostic (PNI), mini assessment short-form (MNA-SF)); and (ii) muscular (creatinine height (CHI)), skeletal muscle (SMI), densitometry...
We developed an algorithm for pulse oximetry where the wavelength dependent photon pathlength is not assumed to be constant. Applying it breath-holding freedivers, we found capturing change in arterial oxygen saturation accurately.
Abstract Purpose: Offshore Ocean Sailing is a highly demanding activity in which subjects are exposed to psychophysical stressors for long time. To better define the physiological adaptations, we investigated stress response of 3-days ocean navigation with disruption circadian rhythms. Methods: 6 male were involved study and provided urine saliva samples before setting sail, during single day inshore sailing, navigation, at arrival, measure oxidative stress, cortisol, nitric oxide...