- Toxic Organic Pollutants Impact
- Effects and risks of endocrine disrupting chemicals
- Air Quality and Health Impacts
- Environmental remediation with nanomaterials
- Mercury impact and mitigation studies
- Recycling and Waste Management Techniques
- Pesticide Residue Analysis and Safety
- Atmospheric chemistry and aerosols
- Engineering Education and Technology
- Adipose Tissue and Metabolism
- Pesticide and Herbicide Environmental Studies
- Insect and Pesticide Research
- Genomics and Chromatin Dynamics
- Robotics and Automated Systems
- Muscle Physiology and Disorders
- Microplastics and Plastic Pollution
- RNA Research and Splicing
- E-commerce and Technology Innovations
- Chemical Analysis and Environmental Impact
- Pesticide Exposure and Toxicity
- Bioinformatics and Genomic Networks
- Lichen and fungal ecology
- Polyamine Metabolism and Applications
- Heavy metals in environment
- Analytical chemistry methods development
Guangzhou Regenerative Medicine and Health Guangdong Laboratory
2021-2025
Zhejiang Institute of Hydraulics & Estuary
2024
Ministry of Ecology and Environment
2022-2024
Research Center for Eco-Environmental Sciences
2018-2022
Chinese Academy of Sciences
2018-2022
University of Chinese Academy of Sciences
2018-2022
University of Science and Technology Beijing
2018
Polychlorinated naphthalenes are teratogenic environmental contaminants. Mother milk is the most important food for nursing infants. The World Health Organization actively promotes breastfeeding its immunological, psychological, and economic advantages. We firstly measured concentrations of polychlorinated in human from 19 provinces China estimated their potential health risks to infants possible sources. Concentrations ranged 211.07 2497.43 pg/g lipid. high prevalence highly toxic...
Halogenated polycyclic aromatic hydrocarbons are carcinogenic and ubiquitous environmental organic pollutants. The abundance sources of these compounds have not been studied in remote environments. We collected analyzed air, soil, lichen, moss samples from the Tibetan Plateau. Concentrations chlorinated were 0.78–4.16 pg/m3 3.11–297 pg/g 260–741 lichens, 338–934 mosses. brominated 0.15–0.59 0.61–72.3 33.5–64.9 20.5–72.5 dominant congeners 9- 2-chlorophenanthrene, 1-chloropyrene,...
We present SiCLAT, which introduces a dCas9-dCas13d cassette into the mouse genome. This model enables stable expression of both dCas9 and dCas13 proteins in diverse cell populations, facilitating concurrent labeling DNA RNA across various types. Using we accurately labeled chromatin loop anchor interactions associated gene transcription during myogenic differentiation. imaging system offers novel means directly observing cis-element corresponding living primary cells, thus providing...
Polychlorinated naphthalenes (PCNs) are highly toxic persistent organic pollutants (POPs) that a relatively new addition to the Stockholm Convention as of 2015. The levels unintentional emissions PCNs from important industrial thermal sources on national scales unclear but for understanding potential human exposure. In this study, an inventory was compiled PCN priority POPs in China. Estimated four typical POP reference year (2014) China were 511.6 kg by mass and 7650.8 mg equivalent. Waste...
Incineration has been the globally controversial and concerned method of solid waste disposal. Energy recovery volume reduction are benefits from incineration, but risk due to release persistent organic pollutants is major public concern in world. In this study, emission including dioxins polychlorinated naphthalenes incineration China was comprehensively evaluated, a relationship between energy benefit pollutant firstly established. The results show that production medical industrial...
MyoD is a skeletal muscle-specifically expressed transcription factor and plays critical role in regulating myogenesis during muscle development regeneration. However, whether myofibers-expressed exerts its metabolic function whole body energy homeostasis vivo remains largely unknown. Here, we report that genetic deletion of Myod male mice enhances the oxidative metabolism and, intriguingly, renders resistant to high fat diet-induced obesity. By performing lipidomic analysis...
Recent studies have shown that the three-dimensional (3D) structure of chromatin is associated with cancer progression. However, roles 3D genome and its dynamics in remains largely unknown. In this study, we investigated hierarchical topologically associating domain (TAD) structures cancers defined a "TAD score (TH score)" for genes, which allowed us to assess TAD nesting level all genes simplified way. We demonstrated levels tumor differ from those normal tissue. Furthermore, were related...
Sichuan pepper, a pungent culinary spice, as well traditional medicinal plant, is widely used in Asian countries. Currently, pesticide combinations are still the most important tools for controlling insect pests to ensure production of pepper. However, there limited data regarding potential hazards posed by residues these substances pepper products. In this study, QuEChERS technique via UPLC-MS/MS multianalysis flonicamid and acetamiprid fresh dried was established with mean recoveries...
The proportion of steel produced using electric arc furnaces (EAFs) is increasing. In this study, polychlorinated dibenzo-p-dioxins and dibenzofurans (PCDD/Fs) concentrations patterns in stack gas samples from three typical EAFs steelmaking plants were determined to allow the contributions PCDD/Fs emissions China be assessed. Samples collection was accomplished by adopting automatic isokinetic sampling technique, then congeners analyzed qualitatively quantitatively isotope dilution...
Chlorinated and brominated polycyclic aromatic hydrocarbons (Cl/Br-PAHs) are emerging persistent organic pollutants. Current knowledge on the emissions of Cl/Br- PAHs is far insufficient for source control, much less their formation mechanisms. In this field study, Cl/Br-PAHs mechanisms were proposed from macro perspective practical secondary metal smelting industries. We found zinc as a significant (9553 ng/m3 in stack gas), exceeding concentrations other sources by 1-2 orders magnitude....
The amount of steel produced using electric arc furnaces (EAFs) has been increasing in recent years. In this study, stack gases from EAFs steelmaking plants were analyzed to determine if they are also dominant sources polybrominated dibenzo-p-dioxin and dibenzofuran (PBDD/F) emissions China. Isotope dilution high-resolution gas chromatography mass spectrometry for qualitative quantitative analysis PBDD/F congeners revealed that the mean concentrations 271.1–9467.8 pg Nm−3 preheating stages...