A5058091727- Dialysis and Renal Disease Management
- Acute Kidney Injury Research
- Central Venous Catheters and Hemodialysis
- Chronic Kidney Disease and Diabetes
- Muscle and Compartmental Disorders
- Sepsis Diagnosis and Treatment
- Mechanical Circulatory Support Devices
- Hemodynamic Monitoring and Therapy
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- COVID-19 Clinical Research Studies
- Renal and Vascular Pathologies
- Renal function and acid-base balance
- Liver Disease and Transplantation
- Electrolyte and hormonal disorders
- Organ Transplantation Techniques and Outcomes
- Cardiac Arrest and Resuscitation
- Liver Disease Diagnosis and Treatment
- Biomedical Research and Pathophysiology
- Potassium and Related Disorders
- Ultrasound in Clinical Applications
- Traumatic Brain Injury and Neurovascular Disturbances
- Parathyroid Disorders and Treatments
- Heart Rate Variability and Autonomic Control
- Antibiotics Pharmacokinetics and Efficacy
- Vascular Procedures and Complications
University of Padua
2006-2025
Azienda Ospedaliera di Padova
2018-2020
International Renal Research Institute of Vicenza
2007-2018
Ospedale San Bortolo
2009-2018
Austin Hospital
2016
Renal Research Institute
2012
University of Virginia Health System
2012
FC Barcelona
2012
Yale University
2006-2007
Carlo Forlanini Hospital
2005
Acute kidney injury (AKI) in the intensive care unit (ICU) is associated with an enhanced mortality. The Dialysis Quality Initiative group has proposed RIFLE (Risk–Injury–Failure–Loss–ESRD) classification to standardize approach AKI. This study was performed estimate AKI incidence ICU patients northeastern Italy and describe clinical characteristics outcomes of on basis their class. A prospective multicenter observational who fulfilled criteria 19 Italy. Data were analyzed using multivariate...
Studies have demonstrated a positive correlation between fluid overload (FO) and adverse outcomes in critically ill patients. The present study aims at defining the impact of hyperhydration on Intensive Care Unit (ICU) mortality risk, comparing Bioelectrical Impedance Vector Analysis (BIVA) assessment with cumulative balance (CFB) recording.We performed prospective, dual-centre, clinician-blinded, observational consecutive patients admitted to ICU an expected length stay least 72 hours....
<b><i>Background:</i></b> Several methods have been developed to assess the hydration status in chronic hemodialysis (HD) patients. The aim of this study was compare body bioimpedance spectroscopy (BIS) with ultrasound (US) lung comet score (ULCs), B-type natriuretic peptide (BNP) and inferior vena cava diameter (IVCD) by US for estimation dry weight before after HD analyze all terms fluid variations induced HD. An additional establish interoperator reproducibility...
Cardiac surgery is a leading cause of acute kidney injury (AKI). Such AKI patients may develop progressive chronic disease (CKD). Others, who appear to have sustained no permanent loss function (normal serum creatinine), still lose renal functional reserve (RFR). We extended the follow-up in observational ‘Preoperative RFR Predicts Risk after Surgery’ study from hospital discharge 3 months for 86 (78.2%) with normal baseline estimated glomerular filtration rate (eGFR), and re-measured high...
Parietal Epithelial Cells (PECs) activation and proliferation are common to several distinct forms of glomerulopathies. Due stimuli, PECs can change a progenitor (CD24+ CD133/2+) or pro-sclerotic (CD44+) phenotype. In addition, PECs, which constantly exposed filtered albumin, known be involved in albumin internalization, but how this mechanism occurs is unknown. We hypothesized that transport via receptor-mediated endocytosis overload may affect the state PECs. Conditionally immortalized...
Antiphospholipid syndrome (APS) can affect the kidneys, leading to renal artery and vein thrombosis, allograft loss following transplantation, microvascular damage referred as aPL-nephropathy (aPL-N). APL-N is a complex frequently underdiagnosed condition characterized by an incomplete understanding of its etiopathogenesis associated with unfavorable outcomes. The 2023 ACR/EULAR classification criteria for APS included aPL-N within domain. gold standard biopsy, revealing lesions acute...
Delftia acidovorans (D. acidovorans) is a non-fermentative, aerobic, Gram-negative bacillus typically found in environmental sources such as soil and water. Although considered an opportunistic pathogen, it has been implicated both immunocompromised immunocompetent individuals. This study presents case of persistent cathether-related bacteraemia 61-year-old haemodialysis patient offers systematic literature review similar cases. The patient, affected by end-stage kidney disease dependent on...
An increase of glomerular filtration rate after protein load represents renal functional reserve (RFR) and is due to afferent arteriolar vasodilation. Lack RFR may be a risk factor for acute kidney injury (AKI), but cumbersome measure. We sought develop non-invasive, bedside method that would indirectly measure RFR. Mechanical abdominal pressure, through compression vessels, decreases blood flow activates the auto-regulatory mechanism which can measured by fall in resistive index (RRI). The...
<b><i>Background:</i></b> Acute kidney injury (AKI) diagnosis is based on a rise in serum creatinine and/or fall urine output. It has been shown that there are patients fulfill AKI definition but do not have AKI, and also with evidence of renal who meet any criteria for AKI. Recently the innovative emerging proteomic technology enabled identification novel biomarkers allow improved risk stratification. <b><i>Methods:</i></b> Tissue inhibitor...
Background Increased oxidant stress is increasingly recognized as a crucial factor in anemia patients with chronic kidney disease. Vitamin E-coated membranes (VECMs) consist of multilayer membrane liposoluble vitamin E on the blood surface allowing direct free radical scavenging at site, which potential clinical benefit. Our objective was to examine effect VECMs hemodialysis (HD). Methods We enrolled 172 stable HD (94 men, 78 women, age 65.4 ± 13.4 years) an open-label multicenter study....
<b><i>Backgound:</i></b> This study was aimed at evaluating the presepsin and procalcitonin levels to predict adverse postoperative complications mortality in cardiac surgery patients. <b><i>Methods:</i></b> A total of 122 patients were enrolled for study. Presepsin measured 48 h after procedure. The primary endpoints renal, respiratory, cardiovascular outcomes mortality. <b><i>Results:</i></b> significantly higher with...
High retention onset (HRO) is the designation for a new class of hemodialysis membranes. A unique characteristic this highly selective and controlled porosity resulting in sieving properties that provide clinically desirable balance between middle/large molecular weight solute removal albumin loss. Another defining feature membrane relatively small fiber diameter, which produces high convective volumes form internal filtration. The aim present study was to estimate, by semi-empirical...
Bisphenol A (BPA) is used in the production of many plastics, which are to build biomaterials that sometimes direct contact with blood. It believed release BPA into bloodstream may give rise cytotoxic events for blood components. The aim present study was perform an vitro investigation observable effect BPA, at increasing concentrations, on monocyte cell line.We incubated cells (U937) 24 h line medium samples (RPMI 1640) different concentrations BPA. We then generated curves evaluate...
Acute Kidney Injury (AKI) is a severe complication affecting many hospitalized patients after cardiac surgery, with negative impacts on short- and long-term clinical outcomes healthcare costs. Recently, interest has been aimed at defining classifying AKI, identifying risk factors developing diagnostic strategies to identify early on. Achieving an accurate diagnosis of AKI crucial issue, because prevention timely detection may help prevent avoid AKI-associated In this retrospective study, we...