A5044533470- Acute Kidney Injury Research
- Muscle and Compartmental Disorders
- Dialysis and Renal Disease Management
- Central Venous Catheters and Hemodialysis
- Mechanical Circulatory Support Devices
- Chronic Kidney Disease and Diabetes
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- COVID-19 Clinical Research Studies
- Clostridium difficile and Clostridium perfringens research
- Atherosclerosis and Cardiovascular Diseases
- Retinal and Optic Conditions
- Organ Donation and Transplantation
- Traumatic Brain Injury and Neurovascular Disturbances
- Hemoglobinopathies and Related Disorders
- Infective Endocarditis Diagnosis and Management
- Erythropoietin and Anemia Treatment
- Liver Disease and Transplantation
- Sepsis Diagnosis and Treatment
- Disaster Response and Management
- Antimicrobial Resistance in Staphylococcus
- Renal Diseases and Glomerulopathies
- Organ Transplantation Techniques and Outcomes
- Vascular Procedures and Complications
- Electrolyte and hormonal disorders
- 3D Printing in Biomedical Research
University of Padua
2018-2024
Azienda Ospedaliera di Padova
2018-2020
Delftia acidovorans (D. acidovorans) is a non-fermentative, aerobic, Gram-negative bacillus typically found in environmental sources such as soil and water. Although considered an opportunistic pathogen, it has been implicated both immunocompromised immunocompetent individuals. This study presents case of persistent cathether-related bacteraemia 61-year-old haemodialysis patient offers systematic literature review similar cases. The patient, affected by end-stage kidney disease dependent on...
Despite limited organ availability and post-transplant complications, kidney transplantation remains the optimal treatment for End-Stage Kidney Disease (ESKD). However, innovative dialysis technologies such as portable, wearable, implantable bioartificial systems are being developed with aim of addressing these issues improving patient care. An ideal device could combine bioreactors blood ultrafiltration to replicate key native cell functions solute reabsorption, secretion, endocrinologic...
COVID-19 often leads to acute respiratory distress syndrome complicated by kidney injury (AKI). The indications for renal replacement therapy these patients are those commonly accepted treat AKI. We describe a continuous veno-venous haemodialysis (CVVHD) protocol AKI, which aims provide the best treatment according particular patient’s and medical personnels’ needs in biohazard settings with limited human technological resources. designed CVVHD high cut-off (HCO) filter regional citrate...
The possibility of keeping liver grafts viable and functioning until transplantation has been explored since the 1950s. However, current modalities Normothermic Machine Perfusion (NMP) have shown several limitations, such as inability to correct electrolytes pH derangements efficiently. Combining NMP with continuous kidney replacement therapy (CKRT) might provide a promising new model overcome these issues.
The key role of arterial hypertension in chonic kidney disease (CKD) progression is widely recognized, but its contribution to tubulointerstitial damage (TID) glomerulonephritis (GN) remains uncertain. Hence, the objective this study clarify whether TID associated with glomerular damage, and at compartment more severe hypertensive patients. included retrospectively consecutive patients referred Nephrology Unit diagnoses primary glomerulonephritis, lupus nephritis (LN), nephroangiosclerosis...
Abstract The dialyzer is the core element of extracorporeal blood purification therapies where several processes take place depending on specific membrane characteristics. To date, filter choice requires preliminary knowledge all its characteristics as they cannot be easily deduced from commercial trade name, hence difficulty in identifying equivalent dialyzers and clearly comparing single‐filter improper for a treatment can determine less‐effective potentially harmful treatments. We aimed...
Critical patients with Acute Kidney Injury (AKI) requiring renal replacement therapy are in most cases eligible only for continuous modalities where the electrolyte balance control is a critical issue. The standard solutions used hemodiafiltration, containing potassium at 2 mmol/L and no phosphorus, determines during extended hypokalemia hypophosphatemia. Therefore, phosphate physiological concentrations were formulated to avoid imbalances reduce ion alterations prolonged treatments, these...
Abstract Background Limited data existed on the burden of coronavirus disease 2019 (COVID-19) renal complications and outcomes most critical patients who required kidney replacement therapy (KRT) during intensive care unit (ICU) stay. We aimed to describe mortality function at 90 days in admitted for COVID-19 KRT. Methods A retrospective cohort study critically ill requiring KRT from March 2020 January 2022 was conducted an Italian ICU a tertiary hospital. Primary outcome secondary days....
Regional Citrate Anticoagulation (RCA) is considered the first-line anticoagulation for Continuous Kidney Replacement Therapy (CKRT). The RCA requires strict protocols and trained staff to avoid unsafe use ensure its benefit. We have analyzed all our CKRT prescriptions from December 2020 April 2022 anonymously, collecting data on CKRT, lab tests, clinical conditions, complications of RCA. In addition, in order better detect citrate accumulation, we performed an protocol by reducing...
Slow continuous ultrafiltration (SCUF) is an extracorporeal therapy able to reduce fluid overload in chronic or acute heart failure resistant diuretics. An in-vitro study demonstrated the SCUF feasibility using a standard infusion central venous catheter (CVC). We describe clinical application of this regional citrate anticoagulation (SCUF-RCA) patient admitted Intensive Care Unit for decompensate with severe systemic To avoid risks deriving from new catheterization, we used pre-existing...
Abstract Iron and erythropoietin deficiencies are determinants of anemia in chronic kidney disease. In hemodialysis (HD) patients, intravenous (IV) iron is associated with a greater hemoglobin (Hb) production better response but may be to hypersensitivity reaction. After the 2013 European Medicines Agency report regarding early detection/management allergic reactions, IV administration dramatically reduced Italian Hemodialysis‐Limited‐Assistance‐Centre (HD‐CAL) where physician present only...
Slow continuous ultrafiltration (SCUF) by central venous catheter (CVC) for hemodialysis is a simple extracorporeal that can reduce and control fluid overload in patients with chronic or acute heart failure unresponsive to medical therapy. In order avoid complications risks related the catheterization standard CVC provide SCUF, considering hospitalized affected congestive commonly undergo placement medications delivering, we tested an vitro model use infusion perform SCUF.We performed SCUF...